视觉空间工作记忆组间差异的神经机制

为考察视觉空间工作记忆（working memory, WM）维持和操作的组间差异及其神经机制,本研究记录了高、低WM组完成延迟再认（维持）任务和心理旋转（操作）任务时的行为和事件相关电位数据。结果发现,在操作任务中,高WM组比低WM组的反应时显著更短;高WM组的中前额叶慢波显著更正、双侧后顶区慢波显著更负,并且两者的波幅显著负相关。在维持任务中,两组被试的反应时无显著差异;高WM组的中前额叶慢波显著更正。结果表明,高WM组的执行注意能力可能更强,能通过有效调节和分配加工资源来表征视觉信息。     

临床诊断中现象与本质的辩证思维

在临床诊断中,疾病的症状、体征往往表现在外,成为现象。疾病本身及其病因,往往深藏于内,成为本质,二者是对立的,需要医师的认真分析、判断,才能辨别清楚。同时,二者又是统一的,要求医师研究大量的症状、体征,透过症状、体征发现准确的疾病及其病因。临床医师只有有效地把握住疾病性质及其病因,才能保证治疗的成功。在临床诊断中,症状、体征与疾病及其病因的关系,有的比较简单,分辨起来困难不大。有的比较复杂,分辨起来稍觉吃力,有的却峰回路转,一种疾病或病因在不同情况下表现出不同的症状,扑朔迷离,令人难以捉摸。疾病的轻重程度不同,有的…     

Recognizing faces defined by texture gradients

Texture gradients can reveal surface orientation in a manner similar to shape from shading, and therefore provide an important cue for object recognition. In this study, we tested whether a complex 3-D object, such as a face, can be identified from texture gradients alone. The stimuli were laser-scanned faces for which the texture element was a fractal-noise pattern mapped onto the 3-D surface. An eight-alternative forced choice task was used in which participants matched a face defined by texture gradients to one of eight faces defined by shape from shading (Experiment 1) or by texture gradients (Experiment 2). On average, participants scored 24% and 18%, respectively, above chance in these experiments. Although this performance was much poorer than the performance based entirely on shape-from-shading stimuli (Experiment 3), the results suggest that texture gradient information may be used to recover surface geometry of complex objects.     

百般谏诤皆为民--晏婴在《晏子春秋》中的谏诤形象

晏婴以极忠尽谏闻名,而其劝谏的主要内容便是要齐君效法古之贤君爱民、重民,体现出中国传统文化中的民本思想.本文以《晏子春秋》为据,描述晏婴的谏诤形象和高超的进谏艺术与技巧.     

2003年诺贝尔医学奖给科学界的多重启示(上)

2003年诺贝尔医学奖授予了两位美英物理学家,劳特布尔和曼斯菲尔德,表彰他们在磁共振成像方面的发现.这些发现导致现代磁共振技术的开发,这一技术标志着医学诊断学和科学研究中的一项突破.该项发现建筑在核磁和核磁共振现象被发现的基础之上.核磁现象的发现及其应用导致了1943、1944和1952年诺贝尔物理学奖的获得.核磁共振现象的发现及其应用导致了1991年和2002年诺贝尔化学奖的获得.这意味着,2003年诺贝尔医学奖是该系列发现中第六个诺贝尔科学奖.     

How are social identities linked to self-conception and intergroup orientation? The moderating effect of implicit theories

Social identity approaches assume that social identification affects both self-conception and intergroup orientation. The authors contend that such social identification effects are accentuated when people hold a fixed view of human character and attribute immutable dispositions to social groups. To these individuals, social identities are immutable, concrete entities capable of guiding self-conception and intergroup orientation. Social identification effects are attenuated when people hold a malleable view of human character and thus do not view social identities as fixed, concrete entities. The authors tested and found support for this contention in three studies that were conducted in the context of the Hong Kong 1997 political transition, and discussed the findings in terms of their implications for self-conceptions and the meaning of social identification.     

Task-effector asymmetries in a rhythmic continuation task

Variability in rhythmic movements has been interpreted as a signature of internal or peripheral noise processes. Grounded in an oscillator interpretation, this study hypothesized that period variability and drift arises from the asymmetry between target period and the limb's intrinsic dynamics. Participants synchronized to 7 target periods, swinging 1 of 3 pendulums in a continuation paradigm; 3 periods were longer, 3 shorter, and 1 identical to the preferred period. Results supported 5 predictions: Drift toward the preferred period was observed that scaled with the asymmetry. Variability was lowest for symmetry conditions and increased with the asymmetry. Variability decreased concomitant with the approach toward the preferred period. Periods exponentially approached the preferred period with positive autocorrelations up to 10 cycles.     

Circadian phase-shifted rats show normal acquisition but impaired long-term retention of place information in the water task

It is thought that circadian rhythms may influence learning and memory processes. However, research supporting this view does not dissociate a mnemonic impairment from other performance deficits. Furthermore, published reports do not specify the type of memory system influenced by the circadian system. The present study assessed the effects of phase shifting on acquisition and expression of place navigation in the water maze, a task sensitive to hippocampal dysfunction. The results showed that phase-shifting circadian rhythms in rats impaired the expression of place information on a retention test but not initial acquisition or encoding of place information. These results suggest that disruption of circadian rhythms may impair consolidation of previously encoded hippocampal place information.     

面孔倒置效应的研究与理论述评

面孔倒置效应是指, 个体对倒置面孔的再认成绩显著低于对正立面孔的再认成绩, 而且, 与普通物体的倒置效应相比, 面孔的倒置效应更大。研究者们针对面孔倒置效应提出了多种理论假说, 两种主要的理论解释是：第一, 倒置面孔破坏了面孔的结构特征, 影响了面孔的整体加工, 所以, 个体对倒置面孔的再认成绩较差; 第二, 眼睛在面孔加工中起重要作用, 尤其在倒置面孔中的作用更明显, 使得倒置面孔N170波幅较高。ERP和fMRI研究提示, 未来研究需要进一步明确眼睛、注意等在面孔倒置效应中的作用。