Reinforcer pathology,probabilistic choice,and medication adherence in patients with multiple sclerosis

The reinforcer pathology model posits that core behavioral economic mechanisms, including delay discounting and behavioral economic demand, underlie adverse health decisions and related clinical disorders. Extensions beyond substance use disorder and obesity, however, are limited. Using a reinforcer pathology framework, this study evaluates medical adherence decisions in patients with multiple sclerosis. Participants completed behavioral economic measures, including delay discounting, probability discounting, and a medication purchase task. A medical decision-making task was also used to evaluate how sensitivity to mild side effect risk and efficacy contributed to the likelihood of taking a hypothetical disease-modifying therapy. Less steep delay discounting and more intense (greater) medication demand were independently associated with greater adherence to the medication decision-making procedure. More generally, the pattern of interrelations between the medication-specific and general behavioral economic metrics was consistent with and contributes to the reinforcer pathology model. Additional research is warranted to expand these models to different populations and health behaviors, including those of a positive health orientation (i.e., medication adherence).     

Centering culture in the treatment of opioid use disorder with American Indian and Alaska Native Communities: Contributions from a National Collaborative Board

American Indian/Alaska Native (AI/AN) communities are disproportionally impacted by the opioid overdose epidemic. There remains a dearth of research evaluating methods for effectively implementing treatments for opioid use disorder (OUD) within these communities. We describe proceedings from a 2-day Collaborative Board (CB) meeting tasked with developing an implementation intervention for AI/AN clinical programs to improve the delivery of medications to treat OUD (MOUD). The CB was comprised of Elders, cultural leaders, providers, individuals with lived experience with OUD, and researchers from over 25 communities, organizations, and academic institutions. Conversations were audio-recorded, transcribed, and coded by two academic researchers with interpretation oversight provided by the CB. These proceedings provided a foundation for ongoing CB work and a frame for developing the program-level implementation intervention using a strength-based and holistic model of OUD recovery and wellbeing. Topics of discussion posed to the CB included engagement and recovery strategies, integration of extended family traditions, and addressing stigma and building trust with providers and clients. Integration of traditional healing practices, ceremonies, and other cultural practices was recommended. The importance of centering AI/AN culture and involving family were highlighted as priorities for the intervention.     

Reframing caring for parents who struggle with substance-use disorders

Nancy Suchman and the colleagues she influenced have produced ground-breaking and attitude-challenging work in understanding how parenting and substance use come together. Dr Suchman and her colleagues make the claim that there is nothing about a substance-use disorder that precludes effective and sensitive caring for children especially with interventions that focus on the parent–child relationship. Suchman's legacy is to highlight how substance use as an illness pulls individuals away from important, caring relationships and limits their giving themselves to those relationships. Restoring the salience of caring relationships and of the individual's ability to care may be as impactful on their substance use as a strict focus on the reduction of drug use and achieving abstinence.     

Some Preliminary Notes on the Objectivity of Mathematics

Topoi - I respond to a challenge by Dieterle (Philos Math 18:311–328, 2010) that requires mathematical social constructivists to complete two tasks: (i) counter the myth that socially...     

Affection deprivation is more aversive than excessive affection: A test of affection exchange theory

Affection exchange theory predicts that both excessive affection and affection deprivation are associated with poorer health, compared with receiving the level of affectionate communication that one desires. A similar yet-untested prediction is that affection deprivation is more aversive than excessive affection. This preregistered study tested both hypotheses on a battery of mental and physical health outcomes, including depression, loneliness, stress, physical pain, frequency of nightmares, and sleep quality, using a Census-matched sample of U.S. American adults (N = 827). As hypothesized, receiving the right amount of affection was associated with more health-supportive scores on all outcomes than either excessive or deficient affection. Similarly, excessive affection was associated with lower depression, loneliness, stress, and pain, and higher sleep quality, than affection deprivation.     

Exploratory study of best friendship dissolution characteristics and psychological difficulties during early adolescence

Few studies have evaluated best friendship dissolutions and especially the circumstances surrounding the dissolutions. In this exploratory study of young adolescents (N = 273, M_age = 11.83 years; 51% boys), we investigate young adolescents' experiences with two types of best friendship dissolution (complete dissolutions, downgrade dissolutions) and two characteristics of such experiences: initiation status (self- versus friend-initiation) and emotional reactions (degree of happiness, anger, sadness, and embarrassment). We also consider whether these characteristics of best friendship dissolutions are related to psychological difficulties (loneliness, depressive symptoms). Results indicated that most young adolescents perceive their friends initiated their recent complete and downgrade dissolutions. When young adolescents did initiate their complete dissolutions, however, they reported less negative (anger) and more positive (happiness) emotional responses. Initiation status was not related to psychological difficulties, but variability in several types of emotional responses (e.g., embarrassment) was related to variability in loneliness and depressive symptoms. Findings underscore the importance of considering not only the type of dissolution, but also the circumstances surrounding dissolutions, during early adolescence.     

Facial comparison behaviour of forensic facial examiners

Facial examiners make visual comparisons of face images to establish the identities of persons in police investigations. This study utilised eye-tracking and an individual differences approach to investigate whether these experts exhibit specialist viewing behaviours during identification, by comparing facial examiners with forensic fingerprint analysts and untrained novices across three tasks. These comprised of face matching under unlimited (Experiment 1) and time-restricted viewing (Experiment 2), and with a feature-comparison protocol derived from examiner casework procedures (Experiment 3). Facial examiners exhibited individual differences in facial comparison accuracy and did not consistently outperform fingerprint analysts and novices. Their behaviour was also marked by similarities to the comparison groups in terms of how faces were viewed, as evidenced from eye movements, and how faces were perceived, based on the made feature judgements and identification decisions. These findings further understanding of how facial comparisons are performed and clarify the nature of examiner expertise.     

IS THERE A DISTINCTIVE QUANTUM THEOLOGY?

Quantum mechanics (QM) is a favorite area of physics to feature in “science and religion” discussions. We argue that this is at least partly because the arcane results of QM can be deployed to make big theological claims by the linguistic sleight of hand of “register switching”—sliding imperceptibly from technical into everyday language using the same vocabulary. We clarify the discussion by deploying the formal mapping of QM into classical statistical mechanics (CSM) via the mathematical device of “Wick rotation.” This equivalence between QM and CSM suggests caution in claiming distinctiveness for quantum theologizing. After outlining two areas in which quantum insights nevertheless resonate with longstanding themes in theological reflection (hiddenness and visualizability), we suggest that both QM and CSM point to a theology of science in which scientists participate in the divine gaze on creation as imago Dei.