Functional activity in the brain of socially deprivated rats produced by an active avoidance test after razobazam (Hoe 175) treatment: a 2-deoxyglucose study

The 2-deoxyglucose (2-DG) autoradiographic method was used to map metabolic activity in the brain of socially deprivated rats during an active avoidance test. The method investigated the effects of razobazam during this learning test. The animals were socially deprivated for 5 weeks. On the first experimental day the animals were trained to avoid a footshock by jumping onto a platform. During training and testing, the total number of avoidance responses was scored. On the second day during one 2-DG session of 40 min, razobazam increased the avoidance score by 18% as compared to controls. Autoradiographs were analyzed using a two-dimensional densitometric method. The analysis of the brain structures showed a 22% reduction of optical density in the nucleus habenularis lateralis, a 25% increase in the caudal part of the nucleus accumbens, and a 13% increase in the frontal cortex in rats treated with razobazam, but no change in the amygdala. These results provide a preliminary concept to explain how the new compound razobazam produced a better learning performance in socially deprivated rats.     

Impact of a preventive social problem solving intervention on children's coping with middle-school stressors

Children receiving 1 year or 1/2 year of a preventive social problem solving program in elementary school were compared with each other and with a no-treatment group upon entry into middle school. One year of training was significantly related to reductions in the severity of a variety of middle-school stressors. Most importantly, a clear mediating role for social problem solving (SPS) skills was found. Children lacking in SPS skills were more likely to experience intense stressors; however, possessing the skills was not necessarily predictive of adjustment to stressors. The results are discussed in terms of the implications of this asymmetry and the strong support given to the value of social problem solving as a preventive intervention for children.     

Cue depreciation: when word fragment completion is undermined by prior exposure to lesser fragments

The ability to think of a previously studied item has often been shown to be impaired when, in one way or another, the extraitem context is changed from study to test. In a series of five experiments, such impairment is induced in a somewhat different way. A fragment (e.g. r-i--rop) of a just-studied word (raindrop) is shown to be less readily completed if it is presented bit by bit (r------p, r----r-p, r-i--r-p, r-i--rop) rather than all at once (Experiments 1, 3, 4, and 5). No such effect is found if the word has not been studied beforehand (Experiments 2, 3, 4, and 5). This pattern of results occurs even when fragments of studied and nonstudied words occur in the same test and under conditions in which subjects cannot tell whether a given fragment is of a studied or nonstudied word (Experiments 4 and 5). In addition, for words that have been studied beforehand, the impairment is shown to increase systematically with the number of steps involved in the presentation of the word fragment (Experiment 3) and also to persist when the time allowed for completion of the final version of the fragment is increased from 4 s to a full minute (Experiment 5).     

Evidence that fixation digits can contribute to visual field asymmetries in lateralized tachistoscopic tasks

Fixation point digits have been widely used in tachistoscopic laterality studies as a simple and convenient means of ensuring unihemispheric projection of stimulus materials to the hemispheres. Previous findings demonstrate that fixation digits do not influence asymmetries in recognition accuracy studies with adult Ss. Present results, comparing four conditions differing in their use of fixation digits, show that in the naming latency paradigm the requirement to remember and report fixation control digits significantly augments RVF superiority. Implications for other latency tasks are discussed.     

Some Arguments Against Analyzing Client Change Graphically

Although single-subject research techniques are relevant and valuable to counselors, analyzing change by graphs alone is open to major sources of error. The author discusses these sources and explores the issues of serial dependency, unreliability of graphs, interjudge disagreement on graphed data, and the use of a more reliable statistical procedure (the time-series statistic) with relevance to the counselor in the field.     

Reasoning on social dilemmas varying in emotional saliency: an adult developmental perspective

The purpose of this study was to provide age-comparative evidence of social cognitive reasoning in adulthood, as mediated by the emotional saliency of tasks tapping postformal reasoning. Specifically, the tasks focused on the ability to resolve discrepant accounts of the same event sequence. It was assumed that less mature thinking may be more evident in reasoning contexts in which emotional factors play a major role. A postformal coding scheme was used to assess levels of reasoning in an interpersonal context. Tasks were administered to 60 subjects--adolescents and young and middle-aged adults. Measures of formal operations, ego level, and verbal ability were also administered. An interaction was found between age and degree of emotional saliency of the task for reasoning level. Specifically, adolescents performed less well on tasks higher in degree of emotional saliency. In addition, developmental differences in postformal reasoning as a function of age and ego level were found.     

Reserve capacity of the elderly in aging-sensitive tests of fluid intelligence: replication and extension

Fluid intelligence belongs to that cluster of intellectual abilities evincing aging loss. To examine further the range of intellectual reserve available to aging individuals and the question of replicability in a new cultural and laboratory setting, 204 healthy older adults (mean age = 72 years; range = 60-86) participated in a short-term longitudinal training study. For experimental subjects, 10 sessions consisted of cognitive training involving two subability tests (Figural Relations, Induction) of fluid intelligence. The pattern of outcomes replicates and expands on earlier studies. Older adults have the reserve to evince substantial increases in levels of performance in fluid intelligence tests. Transfer of training, however, is narrow in scope. Training also increases accuracy of performance and the ability to solve more difficult test items. Difficulty level was estimated in a separate study, with a comparable sample of N = 112 elderly adults. Future research is suggested to examine whether intellectual reserve extends to near-maximum levels of performance.     

Duration of negative practice and the reduction of leg pounding of a traumatically brain-injured adult

This study evaluated the relative efficacy of long (1 minute) and short (15 seconds) durations of negative practice for reducing self-stimulatory leg pounding of a traumatically brain-injured adult. In individual social skill training classes, long negative practice and short negative practice were administered concurrently in an alternating treatments design. Generalization of treatment effects outside of training sessions was assessed during the client's lunch period. The results revealed that both durations of negative practice were equally effective in reducing leg pounding during training sessions. However, the effects of training did not generalize to settings in which the practice contingency was not enforced. Pounding was more frequent and negative practice somewhat less effective during periods of high social stimulation.     

Relationships between adolescent drug use and parental drug behaviors

The present study examined some previously reported relationships between drug use by adolescents and perceived attitudes and behaviors of their parents. An anonymous questionnaire was administered to the student body of an inner-city secondary school for difficult students. Relationships between parental use of drugs and adolescent use of the same drugs were moderate and roughly equivalent across drugs. However, parental use of marijuana was strongly related to the adolescent's use of other, harder drugs such as opiates, cocaine, amphetamines, and barbiturates. This finding is explained within the framework of Kandel's postulated stages of drug initiation. It points to a need for further study of parental influences, which may be increasingly problematic as more individuals who have grown up in our marijuana-accepting society become parents of adolescents.