Depression and immunocompetence: a review of the literature.

Recent evidence suggests that there is a relationship between depression and immunity. On the basis of these studies, it has been argued that depressed mood may increase susceptibility to disease by means of aberrations occurring within the immune system. Empirical research investigating the relationship between depression and immunity is reviewed here. Studies examining both clinical and nonclinical manifestations of depression are discussed and evaluated. This review reveals that indexes of immunocompetence are lower among people exhibiting depressive symptomology and suggests that immune alterations may be more related to dysphoric mood than to specific situations or events. Alternative hypotheses accounting for links between depressed affect and altered immune states are provided, and suggestions for future research are offered.     

Regular and irregular inflection in the acquisition of German noun plurals.

In this paper we study the acquisition of German noun plurals in relation to the question of how children represent regular and irregular inflection. Pinker and Prince (1992) have demonstrated several dissociations between regular and irregular inflection in the English past tense system. However, in English, the default status of -ed is confounded with its high frequency; therefore inflectional systems other than English past tense formation must be examined. The noun plural system in German is particularly interesting, because most nouns have irregular plurals in German and the regular (default) plural is less frequent than several of the irregular plurals. Thus it is unclear how a language learner determines whether German even has a regular plural, and if so what form it takes. Based on longitudinal data from impaired and unimpaired monolingual German-speaking children, we find a striking, statistically significant correlation: plural affixes that are used in overregularizations, namely -n or -s, are left out within compounds. This correlation shows that even impaired children are sensitive to the distinction between regular and irregular morphology. We propose a linguistic analysis of the correlation in terms of Kiparsky's (1982, 1985) level-ordering model plus an additional ordering condition on affixes: default (regular) affixes cannot serve as input to compounding processes.     

A spreading-activation theory of lemma retrieval in speaking.

This paper presents a spreading-activation theory of conceptually driven lemma retrieval--the first stage of lexical access in speaking, where lexical items specified with respect to meaning and syntactic properties are activated and selected. The mental lexicon is conceived of as a network consisting of concept, lemma, and word-form nodes and labelled links, with each lexical concept represented as an independent node. A lemma is retrieved by enhancing the activation level of the node representing the to-be-verbalized concept. This activation then spreads towards the lemma level, and the highest activated lemma node is selected. The theory resolves questions such as the hypernym problem (Levelt, 1989). Furthermore, a computer model that implements the theory is shown to be able to account for many basic findings on the time course of object naming, object categorization, and word categorization in the picture-word interference paradigm. In addition, non-trivial predictions regarding the time course of semantic facilitation for hypernyms, hyponyms, and cohyponyms are experimentally tested, and shown to be valid.     

No counterregulation after breaking the external restraint of children.

At the present, it is unknown how restraint and binge eating/counterregulation are exactly related. Earlier studies on this relationship suffer from two main shortcomings: the studies are all correlational in nature or could not rule out the contribution of confounding variables such as weight loss. The present study investigated whether a break of restraint is a sufficient condition for the occurrence of counterregulation by studying a restrained sample which is not liable to dieting practices and weight loss. The externally imposed restraint on children with regard to eating sweets was broken. However, after breaking their external restraint the children did not counterregulate. It is discussed whether restraint of food intake is really as important for binge eating as it is claimed to be or whether it is merely a consequence or an epiphenomenon of binge eating.     

Problems in recent tests of two cognitive theories of panic.

Four problems in five recent tests of two cognitive theories of panic are discussed: (a) the ambiguity and indistinguishability of the 'body sensations' and 'cognitions' concepts; (b) the uncertain meaning of 'meaningful relationships'; (c) problems arising from differences in Clark's (Behaviour Research and Therapy, 24, 461-470, 1986) theory and Goldstein and Chambless' (Behavior Therapy, 9, 47-59, 1978) theory; (d) the ambiguity of correlational data. Some desiderata for future research on these theories are proposed.     

Predictors of short-term treatment outcome in bulimia nervosa inpatients.

Recent studies, mostly performed on bulimic outpatients, did not find consistent predictors of treatment outcome in bulimia nervosa. This is the first study to investigate anamnestic and clinical factors predictive of the short-term outcome of hospital treatment in 31 female bulimia nervosa patients with a mean age of 22.9 yr. Treatment outcome was assessed by several self-rating instruments measuring different features of the specific and unspecific psychopathology of bulimia nervosa. The most relevant predictors of the outcome of the 8-week hospital treatment were duration of previous inpatient treatments for bulimia, the intensity of anorexic tendency and the pretreatment level of depression. The majority of predictors tested did not show a strong relationship to treatment outcome. The findings are discussed in relation to results of other studies as well as to possible implications for treatment and research.     

The debt of neuropsychology to the epilepsies.

Both neuropsychology and psychology in general have been enhanced markedly by brain-behavior models derived from the study of the epilepsies. A significant body of neuropsychological concepts originated or were confirmed through epilepsy-based treatment and research. These concepts include the peri-Rolandic homunculus, the role of the hippocampal-temporal lobe complex in cognitive memory, hemisphere plasticity for speech in childhood, the intracarotid amytal procedure for determining hemisphere memory patency, and hemisphere-based models of cognition confirmed through human commissurotomy. Personality and social-emotional research in epilepsy are additional areas in which new conceptual models grounded in psychological science can both repay our debt to the epilepsies and provide much needed psychological research and treatment.     

The role of neuropsychology in the assessment and treatment of persons with epilepsy.

Several areas of current interest in the neuropsychology of epilepsy are briefly reviewed in this article. These include variables pertaining to seizures, seizure history, antiepileptic drugs, and methods of neuropsychological evaluation. It is apparent that epilepsy is a multifaceted area: Psychologists not only can be of great assistance to patients with this condition, but may also learn a great deal from this complex disorder.     

Are insomniacs sleepy during the day? A pupillometric assessment.

A biodevelopmental model of insomnia is articulated specifying coordinated nighttime (disturbed sleep pattern) and daytime (no excessive daytime sleepiness) characteristics defining an insomnoid classification in at-risk groups: short sleepers and older adults. Pupillometry is proposed as a useful means of discriminating degree of daytime sleepiness to aid in the differential diagnosis of insomnia and insomnoid states, and the present study tested the discriminative validity of this approach. Noninsomniac (n = 34) and insomniac (n = 29) college students submitted to four 10 min pupillometry sessions tracking daytime sleepiness from morning arising to bedtime. Pupil diameter proved to be an able discriminator of these two groups though substantial overlap of the two distributions was also noted. The results supported the sensitivity of pupillometry in detecting daytime sleepiness, but yielded alternative interpretations. We observed statistical differentiation in insomniac and noninsomniac daytime sleepiness, but substantial, functional overlap between these groups. Assessment and treatment implications arising from the biodevelopmental model were hypothesized.