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51.
Cudnoch-Jedrzejewska A Szczepanska-Sadowska E Dobruch J Puchalska L Ufnal M Kowalewski S Wsół A 《Stress (Amsterdam, Netherlands)》2008,11(4):290-301
The purpose of the present study was to elucidate if rats with myocardial infarction manifest altered responsiveness to central cardiovascular effects of low doses of angiotensin II (ANG II), and if ANG II and vasopressin (VP) cooperate in the central regulation of cardiovascular functions at rest and during stress. Conscious Sprague-Dawley rats with myocardial infarction induced by left coronary artery ligation, or sham-ligated (SL) controls were infused intracerebroventricularly with artificial cerebrospinal fluid (aCSF), ANG II, ANG II + VP or ANG II + V1a receptor antagonist (V1ANT) 4 weeks after cardiac surgery. In the infarcted but not in the SL rats, the resting mean arterial blood pressure (MABP) was significantly elevated by infusions of ANG II and ANG II + VP, while infusion of ANG II + V1ANT was not effective. During administration of aCSF, the pressor, and tachycardic responses to an air-jet stressor were significantly greater in the infarcted than in the SL rats. In the SL rats, the pressor responses to the stressor were significantly greater during infusions of ANG II, ANG II + VP and ANG II + V1ANT than during infusion of aCSF. The tachycardic response in the SL rats was enhanced only by the combined infusion of ANG II + VP. In the infarcted rats, the pressor and the tachycardic responses to the stressor were similar in all groups. It is concluded that: (1) under resting conditions the infarcted rats manifest sensitisation to the central pressor effect of ANG II and that this effect depends on concomitant stimulation of V1a VP receptors, (2) central ANG II may enhance the pressor response to an alarming stressor in the SL rats through an action which does not depend on the concomitant stimulation of V1a receptors, (3) the cooperative action of ANG II and VP is required for intensification of the tachycardic response to the alarming stressor in the SL rats and (4) exaggeration of the cardiovascular responses to the alarming stressor in the infarcted rats cannot be further augmented by an additional stimulation of central ANG II receptors or combined stimulation of ANG II and VP receptors. 相似文献
52.
53.
Ewa Mörtberg Lena Reuterskiöld Maria Tillfors Tomas Furmark Lars-Göran Öst 《Cognitive behaviour therapy》2017,46(4):300-314
Culturally validated rating scales for social anxiety disorder (SAD) are of significant importance when screening for the disorder, as well as for evaluating treatment efficacy. This study examined construct validity and additional psychometric properties of two commonly used scales, the Social Phobia Scale and the Social Interaction Anxiety Scale, in a clinical SAD population (n?=?180) and in a normal population (n?=?614) in Sweden. Confirmatory factor analyses of previously reported factor solutions were tested but did not reveal acceptable fit. Exploratory factor analyses (EFA) of the joint structure of the scales in the total population yielded a two-factor model (performance anxiety and social interaction anxiety), whereas EFA in the clinical sample revealed a three-factor solution, a social interaction anxiety factor and two performance anxiety factors. The SPS and SIAS showed good to excellent internal consistency, and discriminated well between patients with SAD and a normal population sample. Both scales showed good convergent validity with an established measure of SAD, whereas the discriminant validity of symptoms of social anxiety and depression could not be confirmed. The optimal cut-off score for SPS and SIAS were 18 and 22 points, respectively. It is concluded that the factor structure and the additional psychometric properties of SPS and SIAS support the use of the scales for assessment in a Swedish population. 相似文献
54.
The study investigated the influence of predictions on perception-in particular, how strong but erroneous prediction coupled with poor sensory data can trigger misperceptions. Using signal detection, we tested whether predictions induced by a semantic cue change the recognition threshold (criterion) or the subjectively perceived differences between stimuli (sensitivity). In a series of 3 experiments, participants observed pictures of (a) real objects distorted to various extents (targets), (b) noise with elements corresponding to meaningful objects (foils), or (c) nonsense images (noise). Stimuli were preceded either by a semantic cue or by a blank screen with equal probability. Presence of the cue resulted in a more liberal criterion, but only for targets and foils. The cue decreased sensitivity between the distorted targets, but increased sensitivity between the targets and noise-that is, the cue increased between-class differences, but decreased within-class differences. When there was no correspondence between prediction and the sensory input, prediction actually increased the chances of correctly rejecting noise. The influence of the cue was strongest for the moderately distorted targets and foils-when uncertainty related to the bottom-up input was the highest. 相似文献
55.
ABSTRACTThe present study was designed to address the hypothesis that differences and similarities in patterns of attentional processing in recently proposed types of anxiety and depression are connected with the dominant (reactive, regulative) function they play in stimulation processing and their structural components. Participants (N?=?1247) filled out the Anxiety and Depression Questionnaire, which assesses types of anxiety and depression, and completed the Emotional Faces Attentional Test one week later. The obtained results confirmed our prediction and suggested that the proposed typology of anxiety and depression is valid in the adaptive meanings of both phenomena. 相似文献
56.
We present two proof systems for first-order logic with identity and without function symbols. The first one is an extension
of the Rasiowa-Sikorski system with the rules for identity. This system is a validity checker. The rules of this system preserve
and reflect validity of disjunctions of their premises and conclusions. The other is a Tableau system, which is an unsatisfiability
checker. Its rules preserve and reflect unsatisfiability of conjunctions of their premises and conclusions. We show that the
two systems are dual to each other. The duality is expressed in a formal way which enables us to define a transformation of
proofs in one of the systems into the proofs of the other.
Presented by Wojciech Buszkowski 相似文献
57.
Magorzata Lehner Aleksandra Wisowska-Stanek Ewa Taracha Piotr Maciejak Janusz Szyndler Anna Skrzewska Danuta Turzyska Alicja Sobolewska Adam Hamed Andrzej Bidziski Adam Pa
nik 《Neurobiology of learning and memory》2009,92(4):535-543
We designed an animal model to examine the mechanisms of differences in individual responses to aversive stimuli. We used the rat freezing response in the context fear test as a discriminating variable: low responders (LR) were defined as rats with a duration of freezing response one standard error or more below the mean value, and high responders (HR) were defined as rats with a duration of freezing response one standard error or more above the mean value. We sought to determine the colocalisation of c-Fos and glucocorticoid receptors-immunoreactivity (GR-ir) in HR and LR rats subjected to conditioned fear training, two extinction sessions and re-learning of a conditioned fear. We found that HR animals showed a marked decrease in conditioned fear in the course of two extinction sessions (16 days) in comparison with the control and LR groups. The LR group exhibited higher activity in the cortical M2 and prelimbic areas (c-Fos) and had an increased number of cells co-expressing c-Fos and GR-ir in the M2 and medial orbital cortex after re-learning a contextual fear. HR rats showed increased expression of c-Fos, GR-ir and c-Fos/GR-ir colocalised neurons in the basolateral amygdala and enhanced c-Fos and GR-ir in the dentate gyrus (DG) in comparison with LR animals. Our data indicate that recovery of a context-related behaviour upon re-learning of contextual fear is accompanied in HR animals by a selective increase in c-Fos expression and GRs-ir in the DG area of the hippocampus. 相似文献
58.
Contact relations have been studied in the context of qualitative geometry and physics since the early 1920s, and have recently received attention in qualitative spatial reasoning. In this paper, we present a sound and complete proof system in the style of Rasiowa and Sikorski (1963) for relation algebras generated by a contact relation. 相似文献
59.
The Etiology of Individual-Targeted Intolerance: Group Stereotypes and Judgments of Individual Group Members 总被引:1,自引:1,他引:0
Ewa A. Golebiowska 《Political psychology》2000,21(3):443-464
Virtually all scientific writing on attitudes toward political unorthodoxy in the United States focuses on group-targeted tolerance, or the question of whether Americans are willing to extend constitutional rights and freedoms to groups outside the political mainstream. Less is known about the etiology of individual-targeted tolerance, or the question of whether Americans are willing to tolerate the exercise of constitutional rights and freedoms by individuals who belong to unpopular groups. This paper examines the sources of attitudes toward individuals belonging to disliked and stereotyped political groups—in particular, the extent to which political tolerance judgments about gay and racist targets are influenced by attributes of those targets that are either consistent or inconsistent with group stereotypes. In line with expectations, an empirical analysis showed that individuals exhibiting attributes inconsistent with their group's stereotype (whether neutral with respect to stereotypic beliefs or directly challenging them) are tolerated more than those with stereotype-consistent attributes. Because members of political outgroups can control the timing of disclosing their group membership, they have the power to determine whether and to what extent stereotypic beliefs associated with their group will influence the reactions they provoke. This analysis confirms that the impact of stereotypic beliefs on tolerance varies as a function of timing of group membership revelation, although the direction of this interaction depends on the intensity of dislike for the group of which the individual target is a member. 相似文献
60.
Ewa K. Czyz MS Amy S. B. Bohnert PhD Cheryl A. King PhD Amanda M. Price MS Felicia Kleinberg MSW Mark A. Ilgen PhD 《Suicide & life-threatening behavior》2014,44(6):698-709
Individuals with substance use disorders (SUDs) are at high risk of suicidal behaviors, highlighting the need for an improved understanding of potentially influential factors. One such domain is self‐efficacy to manage suicidal thoughts and impulses. Psychometric data about the Self‐Efficacy to Avoid Suicidal Action (SEASA) Scale within a sample of adults seeking SUD treatment (N = 464) is provided. Exploratory factor analysis supported a single self‐efficacy construct. Lower SEASA scores, or lower self‐efficacy, were reported in those with more severe suicidal ideation and those with more suicide attempts, providing evidence for convergent validity. Implications of measuring self‐efficacy in the context of suicide risk assessment are discussed. 相似文献