The role of meaning in gastric cancer patients: relationships among meaning structures,coping, and psychological well-being

ABSTRACT

Background and Objectives: Research demonstrates that the experience of cancer invariably violates patients’ meaning structures, prompting them to use coping strategies to alleviate stress and enhance well-being. The current study aimed to examine the mediating effects of coping strategies in the relationship between global and situational meaning and psychological well-being in gastric cancer patients.

Design and Method: One hundred eighty-seven patients (96 women and 91 men) with gastric cancer completed questionnaires measuring meaning in life, changes of beliefs and goals, coping, and psychological well-being. Participants were between 27 and 82 years of age. They were diagnosed with gastric cancer from 1 to 3.2 years ago. Using Structural Equation Modeling, both the direct and indirect associations between meaning structures, coping, and psychological well-being were examined.

Results: Meaning in life exerted significant indirect effects on psychological well-being through three coping strategies: problem-, emotion-, and meaning-focused. The relationship between changes of beliefs and goals and psychological well-being was also mediated by coping.

Conclusions: Findings suggest that coping strategies are mediators in the relationship between global and situational meaning and psychological well-being. They also provide empirical evidence that in severe cancer-related stress conditions both meaning structures and coping strategies influence patients’ psychological well-being.     

Differential sensitisation to central cardiovascular effects of angiotensin II in rats with a myocardial infarct: relevance to stress and interaction with vasopressin

The purpose of the present study was to elucidate if rats with myocardial infarction manifest altered responsiveness to central cardiovascular effects of low doses of angiotensin II (ANG II), and if ANG II and vasopressin (VP) cooperate in the central regulation of cardiovascular functions at rest and during stress. Conscious Sprague-Dawley rats with myocardial infarction induced by left coronary artery ligation, or sham-ligated (SL) controls were infused intracerebroventricularly with artificial cerebrospinal fluid (aCSF), ANG II, ANG II + VP or ANG II + V1a receptor antagonist (V1ANT) 4 weeks after cardiac surgery. In the infarcted but not in the SL rats, the resting mean arterial blood pressure (MABP) was significantly elevated by infusions of ANG II and ANG II + VP, while infusion of ANG II + V1ANT was not effective. During administration of aCSF, the pressor, and tachycardic responses to an air-jet stressor were significantly greater in the infarcted than in the SL rats. In the SL rats, the pressor responses to the stressor were significantly greater during infusions of ANG II, ANG II + VP and ANG II + V1ANT than during infusion of aCSF. The tachycardic response in the SL rats was enhanced only by the combined infusion of ANG II + VP. In the infarcted rats, the pressor and the tachycardic responses to the stressor were similar in all groups. It is concluded that: (1) under resting conditions the infarcted rats manifest sensitisation to the central pressor effect of ANG II and that this effect depends on concomitant stimulation of V1a VP receptors, (2) central ANG II may enhance the pressor response to an alarming stressor in the SL rats through an action which does not depend on the concomitant stimulation of V1a receptors, (3) the cooperative action of ANG II and VP is required for intensification of the tachycardic response to the alarming stressor in the SL rats and (4) exaggeration of the cardiovascular responses to the alarming stressor in the infarcted rats cannot be further augmented by an additional stimulation of central ANG II receptors or combined stimulation of ANG II and VP receptors.     

Agentic and communal narcissism and satisfaction with life: The mediating role of psychological entitlement and self‐esteem

This study examined the mediational role of self‐esteem (as an enhancement) and psychological entitlement (as a cost) in the relationship between an agentic‐communal model of grandiose narcissism and satisfaction with life. Two hundred and forty‐eight university undergraduate students completed measures of agentic and communal narcissism, self‐esteem, psychological entitlement and satisfaction with life. The findings suggest that there is support for the usefulness of the agentic‐communal model of narcissism, and, consistent with predictions in the wider literature, self‐esteem and psychological entitlement mediated the relationship between agentic‐communal narcissism and life satisfaction.     

Factor solutions of the Social Phobia Scale (SPS) and the Social Interaction Anxiety Scale (SIAS) in a Swedish population

Culturally validated rating scales for social anxiety disorder (SAD) are of significant importance when screening for the disorder, as well as for evaluating treatment efficacy. This study examined construct validity and additional psychometric properties of two commonly used scales, the Social Phobia Scale and the Social Interaction Anxiety Scale, in a clinical SAD population (n?=?180) and in a normal population (n?=?614) in Sweden. Confirmatory factor analyses of previously reported factor solutions were tested but did not reveal acceptable fit. Exploratory factor analyses (EFA) of the joint structure of the scales in the total population yielded a two-factor model (performance anxiety and social interaction anxiety), whereas EFA in the clinical sample revealed a three-factor solution, a social interaction anxiety factor and two performance anxiety factors. The SPS and SIAS showed good to excellent internal consistency, and discriminated well between patients with SAD and a normal population sample. Both scales showed good convergent validity with an established measure of SAD, whereas the discriminant validity of symptoms of social anxiety and depression could not be confirmed. The optimal cut-off score for SPS and SIAS were 18 and 22 points, respectively. It is concluded that the factor structure and the additional psychometric properties of SPS and SIAS support the use of the scales for assessment in a Swedish population.     

When believing is seeing: the role of predictions in shaping visual perception

The study investigated the influence of predictions on perception-in particular, how strong but erroneous prediction coupled with poor sensory data can trigger misperceptions. Using signal detection, we tested whether predictions induced by a semantic cue change the recognition threshold (criterion) or the subjectively perceived differences between stimuli (sensitivity). In a series of 3 experiments, participants observed pictures of (a) real objects distorted to various extents (targets), (b) noise with elements corresponding to meaningful objects (foils), or (c) nonsense images (noise). Stimuli were preceded either by a semantic cue or by a blank screen with equal probability. Presence of the cue resulted in a more liberal criterion, but only for targets and foils. The cue decreased sensitivity between the distorted targets, but increased sensitivity between the targets and noise-that is, the cue increased between-class differences, but decreased within-class differences. When there was no correspondence between prediction and the sensory input, prediction actually increased the chances of correctly rejecting noise. The influence of the cue was strongest for the moderately distorted targets and foils-when uncertainty related to the bottom-up input was the highest.     

Attentional processing of emotional material in types of anxiety and depression

ABSTRACT

The present study was designed to address the hypothesis that differences and similarities in patterns of attentional processing in recently proposed types of anxiety and depression are connected with the dominant (reactive, regulative) function they play in stimulation processing and their structural components. Participants (N?=?1247) filled out the Anxiety and Depression Questionnaire, which assesses types of anxiety and depression, and completed the Emotional Faces Attentional Test one week later. The obtained results confirmed our prediction and suggested that the proposed typology of anxiety and depression is valid in the adaptive meanings of both phenomena.     

Tableaux and Dual Tableaux: Transformation of Proofs

We present two proof systems for first-order logic with identity and without function symbols. The first one is an extension of the Rasiowa-Sikorski system with the rules for identity. This system is a validity checker. The rules of this system preserve and reflect validity of disjunctions of their premises and conclusions. The other is a Tableau system, which is an unsatisfiability checker. Its rules preserve and reflect unsatisfiability of conjunctions of their premises and conclusions. We show that the two systems are dual to each other. The duality is expressed in a formal way which enables us to define a transformation of proofs in one of the systems into the proofs of the other. Presented by Wojciech Buszkowski