The necessity and the value of placebo

The use of placebo in clinical trials has been repeatedly challenged as being unacceptable from an ethical point of view. The present paper responds to this criticism by taking up the issue in the light of the pertinent provisions of the Helsinki Declaration. Examples from different therapeutic areas are given that highlight the importance of placebo in situations in which its use is acceptable according to the Declaration. Particular emphasis is given to the question of active control trials, which, under conditions of low assay sensitivity, may become an ethically less acceptable approach than the use of a placebo control. An earlier version of this paper was presented at an international conference, “Placebo: Its Action and Place in Health Research Today,” held in Warsaw, Poland on 12–13 April, 2003.     

对当代中国新造神运动的忧与思：伪生命科学思潮批判

分析中国伪生命科学产生的文化原因和背景,指出其致命的谎言、骗术与危害;揭露其理论上的荒谬与科学上的无知。并强调开展对这类伪科学产品进行批判运动的意义;同时重新对科学、非科学、伪科学、宗教、神话、迷信等进行划界和定义。医学研究需要正义、需要哲学的引导;在事实的世界之上,必须由价值和意义的世界来把握;医学理论不允许任意杜撰和加工,从这个意义上,医学科学还需要法律来维护其正义     

“神医”现象的剖析

当前“神医”并非罕见,他们常施展浑身解数,或给自己戴上自制的各种“高帽”、“大帽”、什么“国标抗癌协会主席;或假借名人、甚或政界要人的提携,多少沾点余光;或让身世充满着曲折离奇的迷露,对于“神医”的泛滥,当务 急是对全民进行破除迷信、崇尚宾教育,提高全慢旗的心理素质。     

现行《医疗事故处理办法》的修改探析

现行《医疗事故处理办法》颁布实施１０ 年之久,新形势下需要对其进行修改和完善。“办法”的修改应该体现平等保护医患双方合法权益原则,合理界定医疗事故范围,调整医疗事故鉴定委员会的组成,建立完善的证据管理制度,明确医疗事故损失赔偿的范围和额度。     

Perceived stress in prodromal Huntington disease

This study examines perceived stress and its relationship to depressive symptoms, life changes and functional capacity in a large sample of individuals who are positive for the Huntington disease (HD) gene expansion but not yet diagnosed. Participants were classified by estimated proximity to HD diagnosis (far, mid, near) and compared with a non-gene-expanded comparison group. Persons in the mid group had the highest stress scores. A significant interaction between age and time since HD genetic testing was also found. Secondary analyses using data from a different data collection point and including a diagnosed group showed the highest stress scores in the diagnosed group. Possible explanations and implications are discussed.