Effects of SB-205384, a positive modulator of alpha3-subunit-containing GABA-A receptors, on isolation-induced aggression in male mice

GABA-A receptors are involved in the control of aggressive behaviour. Various studies suggest a role for a1-containing GABA-A receptors in modulating aggression. However, the possible involvement of a3 subunit of GABA-A receptors has not been examined. In this study, we analysed the effect of SB-205384 (0.5-4 mg/kg, i.p), a positive modulator of GABA-A receptors containing a3 subunit, on agonistic behaviour elicited by isolation in male mice. Half of the mice were housed during 30 days and employed as experimental or control animals; the remainder were used as and were temporally rendered anosmic by zinc sulphate. Individually housed mice were exposed to anosmic opponents in a neutral area 30 minutes after the drug administration and encounters were videotaped and evaluated using an ethopharmacologically-based analysis. The results indicated that SB-205384 did not produce any significant behavioural changes, suggesting that GABA-A receptors which contain the a3 subunit may not be involved in the modulation of aggression.     

Alcohol drinking parties and consumption of alcohol and other drugs in youth

The main aim of this paper is to analyze the relationships of involvement in the "botellon" (meetings of youth in public places to drink, chat, etc.) with alcohol/other drug abuse and vandalism in young people. A school survey was performed in centres of Compulsory Secondary School (E.S.O.), high school, professional training and University education in Lugo, NW Spain. The sample (aged 12 to 30) was split into three groups according to alcohol use and botellon involvement; drug abuse, drug-related problems and vandalism were assessed in each group. Results indicate that regular botellon attendants display more problems with alcohol and other drugs, as well as higher involvement in vandalism; this relationship is stronger among young students. The increase in adolescent risk associated with the practice of the botellon is explained by peer group pressure to use drugs and the greater accessibility of alcohol/other drugs in these contexts.     

Extinction, spontaneous recovery and renewal of flavor preferences based on taste-taste learning

This paper presents evidence of extinction, spontaneous recovery and renewal in a conditioned preferences paradigm based on taste-taste associations. More specifically, in three experiments rats exposed to a simultaneous compound of citric acid-saccharin solution showed a preference for the citric solution when the preference was measured with a two-bottle test (citric vs. water). Experiment 1 revealed that conditioned preferences were extinguished by repeated presentations of the citric acid solution without the saccharin. In Experiment 2, an additional test trial was introduced 21 days after the extinction treatment. Delayed testing resulted in the recovery of the extinguished preference for the citric, reflecting a spontaneous recovery effect. Experiment 3 revealed a preference renewal effect that was obtained when the extinction was conducted in a context different from that of the remaining experimental stages. The implications of these results are analyzed with attention paid to the mechanisms underlying learning of flavor preferences.     

Narcissism and Cardiovascular Reactivity to Rejection Imagery1

This study examined the interactive effects of imagined rejection and narcissism on cardiovascular reactivity (CVR). Participants completed measures of overt narcissism (Narcissistic Personality Inventory, NPI; Raskin & Hall, 1979 ), overt–covert narcissism ( Margolis & Thomas, 1980 ), and trait self‐esteem. They then imagined 2 scenarios culminating in either interpersonal acceptance or rejection. Systolic (SBP) and diastolic blood pressure (DBP) and heart rate (HR) were assessed before, during, and after the imagery. Overt–covert narcissism was positively associated with task increases in SBP and DBP and recovery elevation of HR following rejection, but not acceptance. Similar effects on SBP were found for the Entitlement/Exploitativeness dimension of the NPI. Lower self‐esteem predicted greater task increases in SBP, DBP, and HR across conditions. Implications for health are discussed.     

The Development of Co-Occurrent Anxiety and Externalizing Problems from Early Childhood: a Latent Transition Analysis Approach

Research on Child and Adolescent Psychopathology - Research into co-occurrent internalizing and externalizing problems during childhood is flourishing. In particular, investigation on the...     

Life aspirations,personality traits and subjective well‐being in a Spanish sample

This study examines the relationships between intrinsic/extrinsic aspirations and subjective well‐being (SWB; positive affect, negative affect, satisfaction with life) in a sample of 583 Spanish adults. Firstly, the results showed that high scores for SWB are related to high scores for intrinsic aspirations and, to a lesser extent, to low scores for extrinsic aspirations; it was also found that intrinsic aspirations are mainly related to positive indicators of well‐being, whereas extrinsic aspirations are mainly associated with negative indicators. Secondly, the study also enabled exploration of the links between the domains of the Five‐Factor Model and aspirations; thirdly, the results showed that intrinsic/extrinsic aspirations predict SWB beyond the Five Factors. The results demonstrate the importance of studying the content of human aspirations for understanding psychological health. Copyright © 2011 John Wiley & Sons, Ltd.     

Latent inhibition in human affective learning

This study presents the results of a new visual procedure designed to generate affective learning, namely the change in the affective rating of a previously neutral stimulus by simply pairing it with a liked or disliked stimulus. Specifically, an experiment was conducted to evaluate the effect of nonreinforced preexposures to the to-be-conditioned stimulus (a non-sense shape) on affective conditioning. This manipulation, intended to produce latent inhibition, typically results in retarded learning when the preexposed stimulus is paired with the unconditioned stimulus. The results revealed that it is possible to modify the affective value of a previously neutral non-sense shape by pairing it with a liked or disliked unconditioned stimulus, and that latent inhibition affects affective conditioning.     

Traits, personal strivings and well-being

Traits and motivational units are two elements of widely acknowledged relevance in personality psychology. In fact, some multi-level models have stressed the differences between traits, which are the most generic and decontextualized units of analysis, and middle-level units, which are more closely related to motivational processes and more contextualized in time, space or specific roles. Personal strivings, which are defined as what people typically intend to do, hold a prominent place among middle-level units. Nevertheless, surprisingly little is still known about the relationship between traits and striving dimensions; likewise, little is known about the inter-relationships between traits, strivings and well-being. In this study, we used the NEO-PI-R, Personal Striving Assessment Packet (PSAP) and various well-being measures (viz., positive affect, negative affect, satisfaction with life and purpose in life) on a sample of 405 adults. We found Neuroticism and Extraversion to be related to perceived efficacy in the struggle for strivings; Extraversion, Agreeableness and Conscientiousness to relate to striving intensity dimensions, and a variety of striving dimensions to be significantly related to well-being. A joint analysis of traits, strivings and well-being revealed that traits may indirectly affect well-being via specific striving dimensions, although the mediational effects are slight and both traits and strivings appear to make separate significant contributions to the prediction of well-being. Broadly speaking, the results suggest that units of analysis originating from rather disparate traditions should be integrated in order to develop a consilient view of personality levels.