Memory Scanning Performance in Healthy Young Adults,Healthy Older Adults,and Individuals with Dementia of the Alzheimer Type

A memory scanning (Sternberg, 1966, 1975) task was administered to healthy young adults, older adults, and two groups of individuals with dementia of the Alzheimer's type (DAT) to determine age- and disease-related changes in the retrieval of information from short-term memory. Healthy older adults, in comparison to healthy young adults, displayed increases in both slopes and intercepts in memory scanning. Individuals at various stages of DAT (very mild, mild, moderate) displayed increases in both slopes and intercepts compared to nondemented age-matched control individuals. There was also some evidence that DAT individuals are more likely to engage in a self-terminating search instead of an exhaustive search of short-term memory.     

The lost cause of mourning

This paper examines the evolution of Jacques Lacan’s concept of mourning from his treatment of Hamlet in Seminar 6, “Desire and Its Interpretation,” to its transformation in the tenth Seminar on “Anxiety.” It is a transformation that occurs in tandem with Lacan’s reconception of anxiety as lack of the lack and his reshaped conception of the objet a as object/cause of desire. The key point is the way that Lacan’s renovated conception upends the common sense notion of mourning, that which assumes that suffering the death of a loved one means accommodating oneself to an absence where there was previously a presence. On the contrary, says Lacan, part of what is most deeply to be mourned is the lack in the Other around which the love relation was constructed. The paper concludes by asking to what extent Lacan’s account of mourning should be distinguished from those of both Hegel and Freud.     

Neuroethics,confidentiality, and a cultural imperative in early onset Alzheimer disease: a case study with a First Nation population

The meaningful consideration of cultural practices, values and beliefs is a necessary component in the effective translation of advancements in neuroscience to clinical practice and public discourse. Society’s immense investment in biomedical science and technology, in conjunction with an increasingly diverse socio-cultural landscape, necessitates the study of how potential discoveries in neurodegenerative diseases such as Alzheimer disease are perceived and utilized across cultures. Building on the work of neuroscientists, ethicists and philosophers, we argue that the growing field of neuroethics provides a pragmatic and constructive pathway to guide advancements in neuroscience in a manner that is culturally nuanced and relevant. Here we review a case study of one issue in culturally oriented neuroscience research where it is evident that traditional research ethics must be broadened and the values and needs of diverse populations considered for meaningful and relevant research practices. A global approach to neuroethics has the potential to furnish critical engagement with cultural considerations of advancements in neuroscience.     

Reasons for the growth of traditional memory span across age

Three studies, covering together the age range from 3 to 16 years, show the relationships between age, short-term memory span, and language abilities. The growth of the traditional memory span in childhood is systematically related to a concomitant growth of language abilities as tested with CELF-3 Screening, two tests of word knowledge, a test of reception of grammar (TROG-2), and the British Picture Vocabulary Test (BPVS). Linear regression and ANCOVA analyses show that the growth of memory span is fully explained by the growth of language abilities in the three studies that covered different subsamples of children. In a confirmatory factor analysis a two-factor model fits the data well and shows that a “crystallised” language factor is strongly related to age, whereas a “fluid” short-term memory factor is unrelated to age. The two-factor model gives support to Baddeley's multicomponent model of working memory, and the current data suggest that the capacity of the phonological store is fully developed in children younger than 4 years old. The authors hold that chunking capacity, highly dependent on language abilities, is a major source of memory span growth with age. Rather than an increase in the number of chunks, or episodes retained in short-term memory (=chunk span), it is argued that childhood memory span development reflects an increase in the size of each chunk (=chunking capacity).     

Measuring pain: an introspective look at introspection

The measurement of pain depends upon subjective reports, but we know very little about how research subjects or pain patients produce self-reported judgments. Representationalist assumptions dominate the field of pain research and lead to the critical conjecture that the person in pain examines the contents of consciousness before making a report about the sensory or affective magnitude of pain experience as well as about its nature. Most studies to date have investigated what Fechner termed "outer psychophysics": the relationship between characteristics of an external stimulus and the magnitude and nature of pain experience. In contrast, Fechner originally envisioned that "inner psychophysics" should investigate the relationship between physiological states and subjective experience. Despite the lack of established research tradition, inner psychophysics has a potential utility in elucidating underlying mechanisms for the production of phenomenal self-report. We illustrate this, using causal modeling analyses of the accuracy of self-reported pain ratings from our laboratory. We submit that the results are inconsistent with representationalist assumptions. Converging trends from several domains of consciousness studies seem to suggest that we need to abandon the unquestioned doctrine of representationalism and search for a more viable framework for understanding the generation of subjective self-report.     

The Assessment of Goal Commitment: A Measurement Model Meta-Analysis

Goals are central to current treatments of work motivation, and goal commitment is a critical construct in understanding the relationship between goals and performance. Inconsistency in the measurement of goal commitment hindered early research in this area but the nine-item, self-report scale developed by Hollenbeck, Williams, and Klein (1989b), and derivatives of that scale, have become the most commonly used measures of goal commitment. Despite this convergence, a few authors, based on small sample studies, have raised questions about the dimensionality of this measure. To address the conflicting recommendations in the literature regarding what items to use in assessing goal commitment, the current study combines the results of 17 independent samples and 2918 subjects to provide a more conclusive assessment by combining meta-analytic and multisample confirmatory factor analytic techniques. This effort reflects the first combined use of these techniques to test a measurement model and allowed for the creation of a database substantially larger than that of previously factor analyzed samples containing these scale items. By mitigating sampling error, the results clarified a number of debated issues that have arisen out of previous small sample factor analyses and revealed a five-item scale that is unidimensional and equivalent across measurement timing, goal origin, and task complexity. It is recommended that this five-item scale be used in future research assessing goal commitment. Copyright 2001 Academic Press.