The Treatment of Anxiety in Autism Spectrum Disorder (TAASD) Study: Rationale,Design and Methods

This paper describes the rationale, design, and methods of the Treatment for Anxiety in Autism Spectrum Disorders study, a three-site randomized controlled trial investigating the relative efficacy of a modular CBT protocol for anxiety in ASD (Behavioral Interventions for Anxiety in Children with Autism) versus standard CBT for pediatric anxiety (the Coping Cat program) and a treatment-as-usual control. The trial is distinct in its scope, its direct comparison of active treatments for anxiety in ASD, and its comprehensive approach to assessing anxiety difficulties in youth with ASD. The trial will evaluate the relative benefits of CBT for children with ASD and investigate potential moderators (ASD severity, anxiety presentation, comorbidity) and mediators of treatment response, essential steps for future dissemination and implementation.     

Illness Perception and Well-Being Among Persons with Multiple Sclerosis and Their Caregivers

This study jointly examined illness beliefs held by persons with multiple sclerosis (PwMS) and caregivers in relation to well-being. A group of 68 PwMS and their caregivers completed the Revised Illness Perception Questionnaire, Psychological Well-being Scales, Satisfaction with Life Scale and Positive Affect and Negative Affect Schedule. Findings revealed that PwMS’ well-being was primarily predicted by their own illness beliefs, and that also caregivers’ well-being was primarily predicted by their own beliefs. Across the two groups, well-being was positively associated with their belief that they understood the disease, and inversely associated with their representations of negative emotions. In addition, among PwMS, well-being was inversely associated with the number of symptoms they specifically attributed to their illness, while among caregivers, well-being was positively associated with beliefs that treatment could control the disease. Based on the study findings, psychoeducational and cognitive-behavioral strategies are suggested to promote well-being among PwMS and caregivers.     

Episodic-like memory in zebrafish

Episodic-like memory tests often aid in determining an animal’s ability to recall the what, where, and which (context) of an event. To date, this type of memory has been demonstrated in humans, wild chacma baboons, corvids (Scrub jays), humming birds, mice, rats, Yucatan minipigs, and cuttlefish. The potential for this type of memory in zebrafish remains unexplored even though they are quickly becoming an essential model organism for the study of a variety of human cognitive and mental disorders. Here we explore the episodic-like capabilities of zebrafish (Danio rerio) in a previously established mammalian memory paradigm. We demonstrate that when zebrafish were presented with a familiar object in a familiar context but a novel location within that context, they spend more time in the novel quadrant. Thus, zebrafish display episodic-like memory as they remember what object they saw, where they saw it (quadrant location), and on which occasion (yellow or blue walls) it was presented.     

Associations of Quality of Life,Physical Activity and Mood States in Women with Breast Cancer Treated with Curative Intent

This study aims to investigate the associations between quality of life, physical activity and mood states in women with breast cancer. A total of 354 women (mean age, 51.74?±?8.63 years; body mass index (BMI), 28?±?5.67 kg/m²) completed the Baecke Physical Activity Questionnaire, Profile of Mood States (POMS), European Organisation for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) and European Organisation for Research and Treatment of Cancer Breast Cancer-Specific Quality of Life Questionnaire (EORTC QLQ-BR23). Pearson’s correlation and multiple linear regressions were used to verify the relations between outcomes and independent variables. Correlations between scores on POMS, Baecke Physical Activity Questionnaire and global health status/quality of life subscale of EORTC QLQ-C30 found associations (p?<?0.01) between physical activity (r?=?0.191), vigour (r?=?0.333) and fatigue (r?=??0.433). Multiple linear regression analysis of the global health status/quality of life subscale of the EORTC QLQ-C30 showed significant differences for vigour (p?<?0.001), social function (p?=?0.003), side effects of systemic therapy (p?=?0.019), arm and breast symptoms (p?<?0.001) and Baecke physical activity score (p?=?0.006). Physical activity is an independent factor related to the quality of life in women with breast cancer. Understanding these variables may influence clinical decisions during treatment and allow positive interventions regarding symptoms, functions and lifestyle.     

Exploring the relationship between Black high school students’ external regulation and intrinsic motivation

Motivation and Emotion - Self-determination theory (SDT) asserts that motivation types, ranging from controlled to autonomous, are independent forms of motivation that differentially emerge from...     

Early motor development and cognitive abilities among Mexican preschoolers

Psychomotricity plays a very important role in children’s development, especially for learning involving reading–writing and mathematical calculations. Evaluate motor development in children 3 years old and its relationship with their cognitive abilities at the age of 5 years. Based on a cohort study, we analyzed the information about motor performance evaluated at 3 years old by Peabody Motor Scale and cognitive abilities at 5 years old. The association was estimated using linear regression models adjusted by mother’s intelligence quotient, sex, Bayley mental development index at 18 months, and quality of the environment at home (HOME scale). 148 children whose motor performance was determined at age 3 and was evaluated later at age 5 to determine their cognitive abilities. Cognitive abilities (verbal, quantitative, and memory) measured by McCarthy Scales. Significant positive associations were observed between stationary balance at age 3 with verbal abilities (β = 0.67, p = .04) and memory (β = 0.81, p = .02) at 5 years. Grasping and visual-motor integration were significant and positively associated with quantitative abilities (β = 0.74, p = .005; β = 0.61, p = .01) and memory (β = 2.11, p = .001; β = 1.74, p = .004). The results suggest that early motor performance contributes to the establishment of cognitive abilities at 5 years. Evaluation and early motor stimulation before the child is faced with formal learning likely helps to create neuronal networks that facilitate the acquisition of academic knowledge.     

For your Eyes Only: A Q-Methodology on the Ontology of Happiness Among Chronically Ill Filipino Elderly in a Penal Institution

Happiness is a positive phenomenon that is universal in nature and is therefore, pertinent to all human beings. However, the definition of happiness differs from person to person, and varies among cultures, economic status, social connectedness, spiritual upbringing and daily situations. An individual’s contextual perception of happiness can change when subjected to bleak conditions such as incarceration wherein inmates, especially those who are old and are experiencing health impairments are stripped off with their customary source of happiness. Since Filipinos are known to be as “happy people,” this study purports to surface the different facets of what constitute happiness in the context of a penal institution in the Philippine setting. The Q-methodology is the primary design used in the study. It combines the objectivity of quantitative approach with the essence of human experiences as explored in qualitative studies. The participants (P-sample) were twenty elderly inmates suffering from chronic ailments. They were asked to arrange 32 statements (Q-sample), derived from the initial interview, in the Q-sort table based on their degree of agreement, which were then further explicated in the post-sort interviews. The results were then subjected to by-person factor analysis with varimax rotation using the PQ Method version 2.11. Five profiles emerged from the by-person factor analysis, namely: (1) ‘Sense of Affinity’, (2) ‘Sense of Opportunity’, (3) ‘Sense of Indemnity’, (4) ‘Sense of Positivity’ and (5) ‘Sense of Resiliency’. The discussion focused on similarities and differences among profiles regarding the four principal themes (familial, social, internal and spiritual components of happiness) derived from the statements used as the Q-sample. The perception of happiness varies from profile to profile. The differences in views on what constitutes happiness among profiles are more prominent than their said similarities. Most leanings are directed toward the familial and spiritual aspects of happiness however, happiness can also be internally motivated and cognitively construed. While happiness has a direct relationship to an individual’s overall perception of well-being, the nurse, being the primary provider of holistic care, plays a pivotal role in promoting optimum health through awareness, knowledge, and appreciation of vis-a vis an unwavering involvement with the unique and distinct psychological and emotional needs of the elderly inmates characterized by respect, openness, authenticity and inter-subjectivity.     

Similarity-based interference in a working memory numerical updating task: age-related differences between younger and older adults

Similarity among representations held simultaneously in working memory (WM) is a factor which increases interference and hinders performance. The aim of the current study was to investigate age-related differences between younger and older adults in a working memory numerical updating task, in which the similarity between information held in WM was manipulated. Results showed a higher susceptibility of older adults to similarity-based interference when accuracy, and not response times, was considered. It was concluded that older adults' WM difficulties appear to be due to the availability of stored information, which, in turn, might be related to the ability to generate distinctive representations and to the process of binding such representations to their context when similar information has to be processed in WM.