Learning related modulation of functional retrieval networks in man

The medial temporal lobe has been implicated in studies of episodic memory tasks involving spatio-temporal context and object-location conjunctions. We have previously demonstrated that an increased level of practice in a free-recall task parallels a decrease in the functional activity of several brain regions, including the medial temporal lobe, the prefrontal, the anterior cingulate, the anterior insular, and the posterior parietal cortices, that in concert demonstrate a move from elaborate controlled processing towards a higher degree of automaticity. Here we report data from two experiments that extend these initial observations. We used a similar experimental approach but probed for effects of retrieval paradigms and stimulus material. In the first experiment we investigated practice related changes during recognition of object-location conjunctions and in the second during free-recall of pseudo-words. Learning in a neural network is a dynamic consequence of information processing and network plasticity. The present and previous PET results indicate that practice can induce a learning related functional restructuring of information processing. Different adaptive processes likely subserve the functional re-organisation observed. These may in part be related to different demands for attentional and working memory processing. It appears that the role(s) of the prefrontal cortex and the medial temporal lobe in memory retrieval are complex, perhaps reflecting several different interacting processes or cognitive components. We suggest that an integrative interactive perspective on the role of the prefrontal and medial temporal lobe is necessary for an understanding of the processing significance of these regions in learning and memory. It appears necessary to develop elaborated and explicit computational models for prefrontal and medial temporal functions in order to derive detailed empirical predictions, and in combination with an efficient use and development of functional neuroimaging approaches, to further the understanding of the processing significance of these regions in memory.     

Syntactic priming and the lexical boost effect during sentence production and sentence comprehension: An fMRI study

Behavioral syntactic priming effects during sentence comprehension are typically observed only if both the syntactic structure and lexical head are repeated. In contrast, during production syntactic priming occurs with structure repetition alone, but the effect is boosted by repetition of the lexical head. We used fMRI to investigate the neuronal correlates of syntactic priming and lexical boost effects during sentence production and comprehension. The critical measure was the magnitude of fMRI adaptation to repetition of sentences in active or passive voice, with or without verb repetition. In conditions with repeated verbs, we observed adaptation to structure repetition in the left IFG and MTG, for active and passive voice. However, in the absence of repeated verbs, adaptation occurred only for passive sentences. None of the fMRI adaptation effects yielded differential effects for production versus comprehension, suggesting that sentence comprehension and production are subserved by the same neuronal infrastructure for syntactic processing.     

Water Mist Punishment for Two Classes of Problem Behaviour

A study with multiple baseline design across situations and response-classes was used to evaluate the effects of a water mist procedure used for punishment of two classes of problem behaviour in a 50-year-old woman with severe mental retardation. Problem behaviour was reduced to less than 5% of baseline. After 19 months the problem behaviour was still reduced, and had stabilized at a level below 10% of baseline. Due to financial economies the local community authorities terminated the treatment, which resulted in a marked increase in the rate of problem behaviour.     

Do computer simulations support the Argument from Disagreement?

According to the Argument from Disagreement (AD) widespread and persistent disagreement on ethical issues indicates that our moral opinions are not influenced by moral facts, either because there are no such facts or because there are such facts but they fail to influence our moral opinions. In an innovative paper, Gustafsson and Peterson (Synthese, published online 16 October, 2010) study the argument by means of computer simulation of opinion dynamics, relying on the well-known model of Hegselmann and Krause (J Artif Soc Soc Simul 5(3):1–33, 2002; J Artif Soc Soc Simul 9(3):1–28, 2006). Their simulations indicate that if our moral opinions were influenced at least slightly by moral facts, we would quickly have reached consensus, even if our moral opinions were also affected by additional factors such as false authorities, external political shifts and random processes. Gustafsson and Peterson conclude that since no such consensus has been reached in real life, the simulation gives us increased reason to take seriously the AD. Our main claim in this paper is that these results are not as robust as Gustafsson and Peterson seem to think they are. If we run similar simulations in the alternative Laputa simulation environment developed by Angere and Olsson (Angere, Synthese, forthcoming and Olsson, Episteme 8(2):127–143, 2011) considerably less support for the AD is forthcoming.     

Religiously Conservative Citizens and the Ideal of Conscientious Engagement: A Comment on Wolterstorff and Eberle

Nicholas Wolterstorff and Christopher J. Eberle have defended the view that the ethics of liberal citizenship allows citizens to publicly support the passage of coercive laws based solely on their religious convictions. They also develop positive conceptions of virtuous citizenship that place moral limits on how citizens may appeal to their religion. The question I address in this essay is whether the limits they impose on citizens’ appeals to their religion are adequate. Since Eberle’s “ideal of conscientious engagement” provides us with the most extensive statement of these limits, it is the primary focus of my attention here. My conclusion is that in its current form, Eberle’s ideal is not constraining enough. In the first section, I argue that Eberle’s ideal does not require citizens to be self-critical enough about their religious and political commitments. In the second section, I highlight a conflict between Eberle’s ideal and the need for citizens to respect the religious freedom of their fellow citizens. I argue that the way to resolve this conflict is to adopt a more fine-grained conception of religious reasons and to hold that citizens should not rely on religious reasons of certain kinds. In the final section, I argue that laws punishing or discouraging homosexual conduct (which Eberle’s ideal would apparently allow) violate what Wolterstorff calls “the Idea of liberal democracy” and so are not the kind of proposal that virtuous citizens can defend.     

Children's Assignment of Gender to Animal Characters in Pictures

Tests showed that 4- to 6-year-old children believe that people can be influenced or “controlled” both by thinking (e.g., both wishful thinking and magical behavior) and by realistic means (e.g., positive reinforcement, example, and group pressure). Belief in control by thinking did not vary by the subjects' sex or age, influence type (wishing or magical behavior), or target response (behavior, emotion, or thought). Quantitative measures, however, suggested that magical behavior was seen by subjects as being more efficient than wishing, and that emotion was considered easier to influence than thinking. Beliefs in control by thinking were not related to a measure of fantasy—reality differentiation (realism).     

Cross-modal associations between vision, touch, and audition influence visual search through top-down attention, not bottom-up capture

Recently, Guzman-Martinez, Ortega, Grabowecky, Mossbridge, and Suzuki (Current Biology : CB, 22(5), 383–388, 2012) reported that observers could systematically match auditory amplitude modulations and tactile amplitude modulations to visual spatial frequencies, proposing that these cross-modal matches produced automatic attentional effects. Using a series of visual search tasks, we investigated whether informative auditory, tactile, or bimodal cues can guide attention toward a visual Gabor of matched spatial frequency (among others with different spatial frequencies). These cues improved visual search for some but not all frequencies. Auditory cues improved search only for the lowest and highest spatial frequencies, whereas tactile cues were more effective and frequency specific, although less effective than visual cues. Importantly, although tactile cues could produce efficient search when informative, they had no effect when uninformative. This suggests that cross-modal frequency matching occurs at a cognitive rather than sensory level and, therefore, influences visual search through voluntary, goal-directed behavior, rather than automatic attentional capture.     

Memory for a staged criminal event witnessed live and on video

Memory for a staged robbery was tested in two groups of participants witnessing the event either live (n = 62) or on video (n = 64). Immediately after the event participants filled out a questionnaire probing memory with emphasis on the timing of the event and robber characteristics. The results showed that participants who watched a video recording of the event reported more details and with a higher accuracy than participants who were present on the scene, but the pattern of memory errors were similar in the two conditions. It is concluded that laboratory experiments may overestimate the memory of eyewitnesses but are otherwise able to simulate essential aspects of memory performance in naturalistic contexts.     

Attachment relationships and health behavior: the mediational role of self-esteem

Many young adults exhibit poor preventive health behavior (e.g., exercise, diet), thereby increasing their long-term risk to health. Recent research has focused on factors related to the development of health behavior in an effort to design effective early interventions. The present study evaluates how attachment styles are related to health behavior in young adults, and the potential mediational role of self-esteem. University students (N = 793) completed surveys assessing attachment style, self-esteem, and health behavior. Results showed that those with secure attachment styles participated in healthier preventive health behavior and had higher self-esteem than those with insecure styles (all ps < 0.05). Self-esteem partially mediated the relation between attachment styles and health behavior (p < 0.01). These results suggest that the development of self-esteem may represent a pathway by which individual styles of interaction with significant others, acquired early in life, can significantly impact key long-term preventive health behaviors.