Specificity of Reward Sensitivity and Parasympathetic-Based Regulation among Children with Attention-Deficit/Hyperactivity and Disruptive Behavior Disorders

Attention-deficit/hyperactivity disorder (ADHD) is associated with disruptionsin reward sensitivity and regulatory processes. However, it is unclear whether thesedisruptions are better explained by comorbid disruptive behavior disorder (DBD)symptomology. This study sought to examine this question using multiple levels ofanalysis (i.e., behavior, autonomic reactivity). One hundred seventeen children (aged 6 to 12 years; 72.6% male; 69 with ADHD) completed theBalloon-Analogue Risk Task (BART) to assess external reward sensitivity behaviorally.Sympathetic-based internal reward sensitivity and parasympathetic-based regulationwere indexed via cardiac pre-ejection period (PEP) and respiratory sinus arrhythmia(RSA), respectively. Children with ADHD exhibited reduced internal reward sensitivity (i.e.,lengthened PEP; F(1,112)=4.01, p=0.047) compared to healthy controls and werecharacterized by greater parasympathetic-based dysregulation (i.e., reduced RSAaugmentation F(1,112)=10.12, p=0.002). However, follow-up analyses indicated theADHD effect was better accounted for by comorbid DBD diagnoses; that is, childrenwith ADHD and comorbid ODD were characterized by reduced internal rewardsensitivity (i.e., lengthened PEP; t=2.47, p=0.046) and by parasympathetic-baseddysregulation (i.e., reduced RSA augmentation; t=3.51, p=0.002) in response to rewardwhen compared to typically developing youth. Furthermore, children with ADHD and comorbid CD exhibited greater behaviorally-based external reward sensitivity (i.e.,more total pops; F(3,110)= 5.96, p=0.001) compared to children with ADHD only (t=3.87, p=0.001) and children with ADHD and ODD (t=3.56, p=0.003). Results suggest that disruptions in sensitivity to reward may be betteraccounted for, in part, by comorbid DBD.Key Words: attention-deficit/hyperactivity disorder, autonomic nervous system,disruptive behavior disorders, reward sensitivityPowered     

Equivalence class formation when responding is separated from sample and comparison stimuli: Working memory,priming, and sorting

The experiment determined whether equivalence class formation required overlap of comparison stimuli and responding. Each trial contained a sample first, a single, nonoverlapping comparison second, and a nonoverlapping response-window (RW) third, during which the participant made one of two responses (2R). All 11 participants formed two 3-member ABC equivalence classes using these “trace-stimulus-pairing two-response with response window” (TSP-2R-RW) trials. After adding a fourth stimulus (D) by CD training, ABCD tests showed immediate expansion to 4-member ABCD classes. When 4-member probes (AD, DA, BD, DB, CD, DC) were administered without 3-member probes, many participants showed decrements in class-indicative responding that then resurged to mastery with test repetition. Thus, 3-member probes enhanced class expansion. Class formation occurred for all participants when responding was temporally dissociated from the comparisons. In a matched, contemporaneously published experiment, where responding occurred during comparisons, only 54% of participants formed the classes. Thus, the comparison-response-separation nearly doubled class formation. Additionally, a special post-class-formation sorting test documented the emergence of two explicit equivalence classes. Finally, we noted a 1:1 correspondence for TSP-2R-RW and priming trials. Since priming measures neural substrates of equivalence classes, TSP-2R-RW trials should do the same.     

Confronting Sexism: Promoting Confrontation Acceptance and Reducing Stereotyping through Stereotype Framing

Sex Roles - Relative to confrontations of other forms of prejudice and stereotyping, confronting gender stereotypes can be challenging, in part, because recipients may be unlikely to accept such...     

Reconsidering Empathy: An Interpersonal Approach and Participatory Arts in the Medical Humanities

Journal of Medical Humanities - The decline of empathy among health professional students, highlighted in the literature on health education, is a concern for medical educators. The evidence...     

Cognitive-Behavioral Conjoint Therapy for PTSD: A Case Study of a Transgender Male Co-Parenting With Former Spouse and Perpetrator of Domestic Violence

Posttraumatic Stress Disorder (PTSD) symptoms have shown to contribute to intimate relationship discord (Taft et al., 2011). Cognitive-Behavioral Conjoint Therapy for PTSD (CBCT for PTSD; Monson & Fredman, 2012) is an evidence-based treatment for PTSD effective at significantly decreasing PTSD symptoms and increasing relationship satisfaction among dyads (Macdonald et al., 2016). To date, there has only been one case study examining the effectiveness of CBCT for PTSD with a sexual minority couple, (same-sex female couple) leaving uncertainty of the effectiveness of this treatment for other sexual minority couples. This case study examined a married couple’s response to treatment, in which the patient identified as a transgender male and his spouse identified as a cisgender female. The patient was diagnosed with PTSD per a Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) total score of 45 (of a maximum of 80). On the CAPS-5, the patient reported a first sexual encounter rape at age 15, from his first marriage with his ex-husband, whom he was dating at the time, as his index trauma. Of note, the patient and his wife currently co-parent two children with the patient’s ex-husband, who perpetrated daily sexual assaults for years during their marriage. Pre-treatment relationship happiness for the couple was “a little unhappy” on the Dyadic Adjustment Scale (DAS) Relationship Happiness Scale. Patient was also diagnosed with Dysthymia and responded well to continued Bupropion for depression. Following completion of the 15-session CBCT for PTSD protocol, the patient’s diagnosis of PTSD was determined to be in remission as evidenced by a post-treatment CAPS-5 total score of 7. At post-treatment the patient rated his relationship happiness as “happy” and his partner “very happy” on the DAS. The couple demonstrated clinically meaningful changes in areas of PTSD and relationship happiness. Functional improvements were also reported in the patient pursuing new employment and hobbies, improved co-parenting between the patient and his wife, improved sexual functioning, and decreased depression symptoms. Treatment gains were maintained at a 1-month and 3-month follow-up. These results demonstrate the effective use of CBCT for PTSD with a sexual minority couple that has continued co-parenting contact with a perpetrator of domestic violence.     

Mental Health Research in Correctional Settings: Perceptions of Risk and Vulnerabilities

With more than half of individuals incarcerated having serious mental health concerns, correctional settings offer excellent opportunities for epidemiological, prevention, and intervention research. However, due to unique ethical and structural challenges, these settings create risks and vulnerabilities for participants not typically encountered in research populations. We surveyed 1,224 researchers, Institutional Review Board (IRB) members, and IRB prisoner representatives to assess their perceptions of risks and vulnerabilities associated with mental health research conducted in correctional settings. Highest ranked risks were related to privacy, stigma, and confidentiality; lowest ranked risks were related to prisoners’ loss of privileges or becoming targets of violence due to having participated in research. Cognitive impairment, mental illness, lack of autonomy, and limited access to services emerged as the greatest sources of vulnerability; being male, being female, being older than age 60, being a minority, and being pregnant were the lowest ranked sources of vulnerability. Researchers with corrections experience perceived lower risks and vulnerabilities than all other groups, raising the question whether these researchers accurately appraise risk and vulnerability based on experience, or if their lower risk and vulnerability perceptions reflect potential bias due to their vested interests. By identifying areas of particular risk and vulnerability, this study provides important information for researchers and research reviewers alike.     

Recognition and rejection each induce forgetting

Psychonomic Bulletin & Review - Recognition-induced forgetting, whereby the recognition of targeted memories induces the forgetting of related memories, results from the recognition of old...     

Impact of a television film on attitudes toward mental illness

The possible impact of a prime time television film portraying a mentally ill killer was investigated. Groups of college students were shown the film with and without a film trailer reminding viewers that violence is not characteristic of mentally ill persons. A third group viewed a film not about mental illness. Postfilm responses to the Community Attitudes toward the Mentally Ill scale indicated that those who saw the target film expressed significantly less favorable attitudes toward mental illness and community care of mentally ill persons than did those who saw the control film, regardless of whether of not they received the trailer along with the target film. Results support concerns that media depictions add to mental illness stigma and also suggest that corrective information alone may be sufficient to counteract the stigmatizing impact of such audience-involving mass media portrayals.