Cognitive development in absence epilepsy during long-term follow-up

Absence epilepsy (AE) has been associated with lower than average cognitive functioning, which are clinically relevant in some and may predispose to problems later in life. This study aimed to assess cognitive development during long-term follow-up in children with AE. Thirty-one children with AE, who had undergone two neuropsychological assessments between 2010 and 2017 were analyzed retrospectively. Cognitive measurements were 1.7 ± 0.95 years apart. The difference in neurocognitive test scores was assessed on a group level and on an individual level using reliable change methodology. Results show that sustained attention was lower at the first measurement compared to the normative mean. Sustained attention improved during follow-up and 7 out of 14 children showed improvement after correction for practice effects. Receptive vocabulary showed a decline over time, but did not differ from the normative mean. Significant lower mean group scores were present for performance IQ, perceptual organization, processing speed, simple reaction times, and visual motor integration, while being stable over time in the majority of children. Cognitive development was not associated with seizure freedom. Mild-to-severe academic underachievement was present in 65% and comorbidities that might affect learning in 38%. This study in children with AE showed improvement in sustained attention during long-term follow-up while other cognitive weaknesses persisted over time, regardless of seizure freedom.     

Dynamic properties of an ultrafine-grained Mg–Zn–Zr alloy

The effect of ultrafine-grained structure formation in Mg–Zn–Zr alloy ZK60 on its mechanical response was investigated at strain rates ranging from quasi-static to dynamic regimes. The study demonstrated that the strength characteristics of the material rise significantly with increasing strain rate, while its ductility is reduced. These effects are particularly pronounced in the dynamic loading regime, at strain rates in the (1?5)?×?10²?s^?1 range. In the ultrafine-grained alloy ZK60, the energy absorption per unit volume, W, is enhanced by grain refinement by a factor as high as eight for the highest strain rate of 5?×?10²?s^?1 investigated. The analysis is focused on the microstructure features that bring about the observed improvement of the tensile characteristics, as well as the deformation and fracture modes prevalent at different strain rates. The results obtained contribute to the exploration and understanding of dynamic behaviour of magnesium alloys.     

Malebranche and the General Will of God

Central to Nicolas Malebranche’s theodicy is the distinction between general volitions and particular volitions. One of the fundamental claims of his theodicy is that although God created a world with suffering and evil, God does not will these things by particular volitions, but only by general volitions. Commentators disagree about how to interpret Malebranche’s distinction. According to the ‘general content’ interpretation, the difference between general volitions and particular volitions is a difference in content. General volitions have general laws as their content and particular volitions have particular contents. The ‘particular content’ interpretation holds that all of God’s volitions have particular contents. The difference between general and particular volitions is whether the content of the volition is in accordance with the laws that God has established. A proper interpretation of this distinction is essential to understanding Malebranche’s theodicy, as well as his account of occasionalism and God’s causal activity in the world. In this paper, I defend the ‘particular content’ interpretation of the distinction.     

Reverse Subtyping: The Effects of Prejudice Level on the Subtyping of Counterstereotypic Outgroup Members

Although many anti-bias interventions try to overcome stereotypes by presenting positive and/or counterstereotypic members of the outgroup, people often subtype these members and refuse to see them as typical of the outgroup. Although subtyping has been shown to be a common phenomenon, it is unclear if preexisting attitudes moderate this process. The current study examined whether preexisting prejudice levels would moderate the subtyping process. Specifically, it was found that although high-prejudiced individuals subtyped a positive racial outgroup member, low-prejudiced individuals demonstrated the opposite pattern and subtyped negative outgroup members as being atypical. This suggests that although the subtyping phenomenon may be universal, its expression is moderated by preexisting intergroup attitudes.     

When Pain Does Not Heal: The Common Antecedents and Consequences of Chronic Social and Physical Pain

Researchers find that social and physical pain overlap in acute episodes. In this article, we hypothesize that social and physical pain overlap in chronic conditions as well. To support this hypothesis, we reviewed the literature and introduced the Integrated Chronic Pain Model (ICPM), which posits that chronic social and physical pain overlap in their psychological antecedents and consequences. Specifically, the ICPM proposes several common factors that play a role in the onset and maintenance of both social and physical chronic pain and indicates that both forms of pain persistently impair self-regulatory resources and threaten the same basic psychological needs.     

Different origins and meanings of acute acting-out in an inpatient psychotherapeutic setting

In this paper I describe four different sources of acute acting-out behaviour as may be observed in long-term hospitalised patients suffering from severe personality disorders. I hope to demonstrate that acute psychological distress does not happen in a vacuum, but that specific intrapsychic and interpersonal dynamics within the hospital setting are at the root of what appears overtly as nonspecific emotional and behavioural disturbance. I argue that the hospital team's correct insight into the factors underlying acute acting-out is crucial to the implementation of therapeutic interventions aimed to decrease the patient's disturbed state of mind.     

Remembering and repeating in multiple personality

This paper is a case-history of a student in his early twenties tortured by different personalities of different ages and sexes vying for control of his body. Guilt over an incestuous relationship with his mother is uncovered and understood in the context of his whole life. Confusion between memories of fantasies, memories of sleep dreams, memories of daydreams, and memories of actual memories are described, the elucidation of which lead to clearer thinking and memory, and more tolerance for the previously distorted affectladen situations of his past. Thus his belief that he was experimented on in an alien spaceship becomes the memory of an operating-room diagnostic experience.

A hypothesis is put forward that the separate personalities in the multiple personality are not simply the products of ego splits, but are at the instant they are formed a ‘doubling’ of the personality that is being copied. Immediately thereafter, splitting mechanisms create differences between the two separate personalities, using projective and introjective mechanisms. Integration of the various personalities, the ultimate goal in treatment, is made difficult by the patient's fear of loss of self through fragmentation, when the self is felt to be in danger of being intruded upon.     

On some types of hallucinatory experience

There are types of non-visual hallucinatory experience which occur in the psychoses other than those which have a critical and derogatory content. Wish-fulfilment plays an important part in the formation of the content of these hallucinations. In others, ‘persecutory’ anxiety also occurs. A comparison is made between hallucinatory and dream content. An hypothesis is presented to account for the perceptual quality of these hallucinatory experiences. The therapeutic implications of these considerations concludes this presentation.     

A PROCESS MODEL OF CAUSAL REASONING IN COMPREHENSION

Many readers and reading theorists alike hold a "common sense" intuition that omissions and substitutions made while reading orally are caused by the reader failing to see the omitted or substituted word, or looking at it for too short a time. In this study the eye movements of college age readers were recorded while they read aloud and then analyzed to see if there is a causal relationship between "careless" eye movements and oral reading omissions and substitutions. Results indicate that, contrary to conventional wisdom, most omitted and substituted words are visually examined, and examined thoroughly, prior to being orally omitted or substituted. These findings are discussed in a context that views reading as a perceptual, interactive, and constructive process.     

Temporal characteristics of the surprise reaction induced by schema-discrepant visual and auditory events

Abstract

Two experiments investigated the effects of a schema-discrepant event on the surprise reaction. Schema-discrepancy concerned a physical feature of irrelevant distractor words that were presented while the subjects performed a choice reaction time task. The stimulus onset asynchrony (SOA) between the distractors and the task-relevant stimuli was manipulated in both experiments. The occurrence of the schema-discrepant event led to subjective feelings of surprise and enhanced recall of the stimulus material. In Experiment 1, the presentation of a schema-discrepant auditory event resulted in a pronounced increase of reaction time (RT) with a 0.2sec SOA but not with a 1.5sec SOA. In Experiment 2, the effects of both fixed and variable SOAs of four different lengths (simultaneous onset, 0.5sec, 1sec, or 2sec SOA) were investigated within a visual task context. The increase of RT was found to be most pronounced with SOAs of 0.5sec and lsec respectively, and more pronounced with variable than with fixed SOAs, especially with a simultaneous onset. These results provide information about the temporal characteristics of the inhibitory component of the surprise reaction, and suggest that the inhibitory effects of surprise depend considerably on the subjects' state of preparation for the experimental task.