BDNF serum levels in subjects developing or not post-traumatic stress disorder after trauma exposure

Post-traumatic stress disorder (PTSD) is a syndrome resulting from exposure to a severe traumatic event that poses threatened death or injury and produces intense fear and helplessness. The neural structures implicated in PTSD development belong to the limbic system, an important region for emotional processing. Brain-derived neurotrophic factor (BDNF) is a neurotrophin that serves as survival factor for selected populations of central nervous system (CNS) neurons and plays a role in the limbic system by regulating synaptic plasticity, memory processes and behavior. Impaired BDNF production in the brain can lead to a variety of CNS dysfunctions including symptoms associated with PTSD. However, so far fewer studies have investigated this neurotrophin in patients with PTSD. Furthermore, given the multiple role of BDNF in various CNS disorders, it cannot be excluded that traumatic events per se may influence neurotrophin levels, without a direct association to the PTSD syndrome.     

Around the world,adolescence is a time of heightened sensation seeking and immature self‐regulation

The dual systems model of adolescent risk‐taking portrays the period as one characterized by a combination of heightened sensation seeking and still‐maturing self‐regulation, but most tests of this model have been conducted in the United States or Western Europe. In the present study, these propositions are tested in an international sample of more than 5000 individuals between ages 10 and 30 years from 11 countries in Africa, Asia, Europe and the Americas, using a multi‐method test battery that includes both self‐report and performance‐based measures of both constructs. Consistent with the dual systems model, sensation seeking increased between preadolescence and late adolescence, peaked at age 19, and declined thereafter, whereas self‐regulation increased steadily from preadolescence into young adulthood, reaching a plateau between ages 23 and 26. Although there were some variations in the magnitude of the observed age trends, the developmental patterns were largely similar across countries.     

Trajectories of Italian Children’s Peer Rejection: Associations with Aggression,Prosocial Behavior,Physical Attractiveness,and Adolescent Adjustment

In the present study, the predictors and outcomes associated with the trajectories of peer rejection were examined in a longitudinal sample of Italian children (338 boys, 269 girls) ages 10 to 14 years. Follow-up assessments included 60% of the original sample at age 16–17. Low, medium, and high rejection trajectory groups were identified using growth mixture models. Consistent with previous studies, we found that (a) being less prosocial and more physically aggressive at age 10 was characteristic of those children with the high rejection trajectory; (b) being less attractive was related to higher peer rejection from age 10 to 14; and (c) boys with a high rejection trajectory showed high levels of delinquency and anxiety-depression and low levels of academic aspiration at age 16–17, whereas girls with a high rejection trajectory showed low levels of academic aspiration and social competence at age 16–17. Our findings indicate the detrimental consequences of peer rejection on children’s development and adjustment and shed light on the mechanisms that contribute to maintaining or worsening (e.g., being attractive, prosocial, and aggressive) a child’s negative status (e.g., being rejected) within his or her peer group over time.     

Modeling Nonstationary Emotion Dynamics in Dyads using a Time-Varying Vector-Autoregressive Model

Emotion dynamics are likely to arise in an interpersonal context. Standard methods to study emotions in interpersonal interaction are limited because stationarity is assumed. This means that the dynamics, for example, time-lagged relations, are invariant across time periods. However, this is generally an unrealistic assumption. Whether caused by an external (e.g., divorce) or an internal (e.g., rumination) event, emotion dynamics are prone to change. The semi-parametric time-varying vector-autoregressive (TV-VAR) model is based on well-studied generalized additive models, implemented in the software R. The TV-VAR can explicitly model changes in temporal dependency without pre-existing knowledge about the nature of change. A simulation study is presented, showing that the TV-VAR model is superior to the standard time-invariant VAR model when the dynamics change over time. The TV-VAR model is applied to empirical data on daily feelings of positive affect (PA) from a single couple. Our analyses indicate reliable changes in the male’s emotion dynamics over time, but not in the female’s—which were not predicted by her own affect or that of her partner. This application illustrates the usefulness of using a TV-VAR model to detect changes in the dynamics in a system.     

The structure and process of emotional experience following nonmarital relationship dissolution: dynamic factor analyses of love, anger, and sadness

Dynamic factor analysis was used to examine the structure and process of daily emotions in a sample of young adults following a romantic breakup. Participants completed a daily diary for 4 weeks reporting on their love/longing for their ex-partner, anger, and sadness. Using a lag-1 process factor analysis model, results revealed that love/longing, sadness, and anger could be reliably distinguished as separate but correlated mood states in a trivariate model. Four emotional dynamics (amplification, reversing, persistence, and cooccurrence) were operationalized and investigated. Differences in these dynamics were observed on the basis of overall adjustment to the separation and attachment styles. Findings are discussed in terms of attachment and contemporary emotion theories, as well as the need to operationalize time-based affective processes.     

Factor analysis of Wechsler Adult Intelligence Scale-Revised in developmentally disabled persons

The results of previous studies on the factorial structure of Wechsler Intelligence Scales are somewhat inconsistent across normal and pathological samples. To study specific clinical groups, such as developmentally disabled persons, it is useful to examine the factor structure in appropriate samples. A factor analysis was carried out using the principal component method and the Varimax orthogonal rotation on the Wechsler Adult Intelligence Scale (WAIS-R) in a sample of 203 developmentally disabled persons, with a mean age of 25 years 4 months. Developmental disability ranged from mild to moderate. Partially contrasting with previous studies on normal samples, results found a two-factor solution. Wechsler's traditional Verbal and Performance scales seems to be more appropriate for this sample than the alternative three-factor solution.     

The nature of residual cost in regular switch response factors

Two experiments are presented that compare the residual cost found when switching from one task to another under predictable conditions. The aim of the study was to explore the roles played by the stimulus, the response, or both in the process of the mental set reconfiguration necessary to switch between two tasks. The experiments tested [Rogers, R. D., & Monsell, S. (1995). Cost of a predictable switch between simple cognitive tasks. Journal of Experimental Psychology: General, 124, 207-231] stimulus-cued-completion hypothesis and [Schuch, S., & Koch, I. (2003). The role of response selection for inhibition of task sets in task shifting. Journal of Experimental Psychology: Human Perception and Performance, 29, 92-105] hypothesis of response selection as the key factor in the nature of switch cost. In the first experiment, two conditions were created that varied in terms of a Go/No-Go signal: The Go trials were a replication of [Tornay, F. J., & Milán, E. G. (2001). A more complete task-set reconfiguration in random than in predictable task switch. The Quarterly Journal of Experimental Psychology, 54A, 785-803 Experiment 3]; The No-Go trials were identical to the first condition, except that participants did not execute a response in the trial n-1 (Schuch & Koch, 2003). In addition, the percentage of Go and No-Go trials was manipulated. The results showed that the cost was significant only in the high Go signal-frequency case (Experiment 2), with an abrupt offset in Go trials and a gradual offset in No-Go trials. Based on the results of these experiments, it was concluded that the crucial factor to complete a mental set reconfiguration is response-related and not stimulus-related.     

The validity of the hospital anxiety and depression scale and the geriatric depression scale in Parkinson's disease

We assessed the concurrent validity of the Hospital Anxiety and Depression Scale (HADS) and the Geriatric Depression Scale (GDS) against the Hamilton Rating Scale for Depression (Ham-D) in patients with Parkinson's disease (PD). Forty-six non-demented PD patients were assessed by a neurologist on the Ham-D. Patients also completed four mood rating scales: the HADS, the GDS, the VAS and the Face Scale. For the HADS and the GDS, Receiver Operating Characteristics (ROC) curves were obtained and the positive and negative predictive values (PPV, NPV) were calculated for different cut-off scores. Maximum discrimination between depressed and non-depressed PD patients was reached at a cut-off score of 10/11 for both the HADS and the GDS. At the same cut-off score of 10/11 for both the HADS and the GDS, the high sensitivity and NPV make these scales appropriate screening instruments for depression in PD. A high specificity and PPV, which is necessary for a diagnostic test, was reached at a cut-off score of 12/13 for the GDS and at a cut-off score of 11/12 for the HADS. The results indicate the validity of using the HADS and the GDS to screen for depressive symptoms and to diagnose depressive illness in PD.     

Place and summation coding for canonical and non-canonical finger numeral representations

Fingers can be used to express numerical magnitudes, and cultural habits about the fixed order in which fingers are raised determine which configurations become canonical and which non-canonical. Although both types of configuration carry magnitude information, it has been shown that the canonical ones are recognized faster and directly linked to number semantics. Here we tested whether this difference is a consequence of differences in the qualitative way of processing the two types of configurations. When participants named Arabic digits (Experiment 1) or verbal numerals (Experiment 2) primed by canonical and non-canonical finger configurations, qualitatively different priming patterns were observed for the two types of configurations. Canonical configurations activated a place coding representation, with priming spreading to close smaller and larger magnitudes as a function of the prime–target distance. Conversely, non-canonical configurations activated a summation coding representation priming smaller and equal magnitudes independently of the prime–target distance, and larger targets depending on this distance.