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Extracting the statistical regularities present in the environment is a central learning mechanism in infancy. For instance, infants are able to learn the associations between simultaneously or successively presented visual objects (Fiser & Aslin, 2002 ; Kirkham, Slemmer & Johnson, 2002 ). The present study extends these results by investigating whether infants can learn the association between a target location and the context in which it is presented. With this aim, we used a visual associative learning procedure inspired by the contextual cuing paradigm, with infants from 8 to 12 months of age. In two experiments, in which we varied the complexity of the stimuli, we first habituated infants to several scenes where the location of a target (a cartoon character) was consistently associated with a context, namely a specific configuration of geometrical shapes. Second, we examined whether infants learned the covariation between the target location and the context by measuring looking times at scenes that either respected or violated the association. In both experiments, results showed that infants learned the target–context associations, as they looked longer at the familiar scenes than at the novel ones. In particular, infants selected clusters of co‐occurring contextual shapes and learned the covariation between the target location and this subset. These results support the existence of a powerful and versatile statistical learning mechanism that may influence the orientation of infants’ visual attention toward areas of interest in their environment during early developmental stages. A video abstract of this article can be viewed at: https://www.youtube.com/watch?v=9Hm1unyLBn0  相似文献   
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This paper explores some of the ways in which sexuality can intrude into the psychotherapeutic relationship and present both opportunities and risks to our work with adolescents. It highlights some of the complexities of this area of the clinical encounter, exploring the particular difficulties encountered by both patient and therapist when sexuality emerges in the transference and countertransference. While we are well aware of the centrality of sexual development during adolescence, far less has been written about the way in which sexuality and the erotic transference emerges and impacts on both patient and therapist. Given the profoundly unsettling nature of this area of work and its capacity to disrupt our thinking and psychic equilibrium, it is easy to underestimate how much we are drawn to avoid, negate and defend ourselves against registering such experiences. Through the discussion of clinical material with two adolescent patients, this paper explores some of these dynamics, addressing some of the technical dilemmas that frequently challenge us in this area of work. These include questions about whether and when it is therapeutically important and effective to take up and interpret the emergence of sexuality more directly in the transference and some of the risks to our patients when we ‘play safe’ and fail to do so. Most importantly, this paper aims to facilitate further thinking and discussion about an important but uncomfortable and easily neglected area of our work.  相似文献   
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To determine familial risk of early suicide, data on cause of death of all Dutch residents aged 20-55 years who died between 1995 and 2001 were linked to data of their parents. Men whose father died by suicide had a higher odds of suicide themselves, relative to men whose father died of other causes (Odds Ratio (OR): 2.5; 95% confidence interval: 1.8-3.6). This effect was slightly stronger in the case of mother's suicide (OR: 3.4; 2.3-5.0). The same effect was observed for women, for suicide by father (OR: 2.2; 1.3-3.7) and mother (OR: 4.6; 2.6-8.0). The odds of suicide increased with decreasing age at death of parent. Parental suicide is predictive for offspring suicide. Our data suggest that the predictive value is higher in case the mother died by suicide, particularly if the mother died by suicide at a young age.  相似文献   
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Neuronal synchronisation at gamma frequencies (30-100 Hz) has been implicated in cognition and memory. Gamma oscillations can be studied in various in vitro models, but their in vivo validity and their relationship with reference memory remains to be proven. By using the natural variation of wild type C57bl/6J mice, we assessed the relationships between reference memory and gamma oscillations recorded in hippocampal area CA3 in vivo and in vitro. Local field potentials (LFPs) were recorded from area CA3 in behaviourally-characterised freely moving mice, after which hippocampal slices were prepared for recordings in vitro of spontaneous gamma oscillations and kainate-induced gamma oscillations in CA3. The gamma-band power of spontaneous oscillations in vitro correlated with that of CA3 LFP oscillations during inactive behavioural states. The gamma-band power of kainate-induced oscillations correlated with the activity-dependent increase in CA3 LFP gamma-band power in vivo. Kainate-induced gamma-band power correlated with Barnes circular platform performance and object location recognition, but not with object novelty recognition. Kainate-induced gamma-band power was larger in mice that recognised the aversive context, but did not correlate with passive avoidance delay. The correlations between behavioural and electrophysiological measures obtained from the same animals show that the gamma-generating capacity of the CA3 network in vitro is a useful index of in vivo gamma strength and supports an important role of CA3 gamma oscillations in spatial reference memory.  相似文献   
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Aim: To determine whether or not clients' perceptions of microaggressions varied based on their own and the therapist's race/ethnicity and whether or not they would be negatively related to the effectiveness of therapy and if the working alliance would mediate this effect. Method: The study utilised a cross‐sectional, retrospective, methodology. Clients were recruited from a large university counselling centre in the United States (N=232 clients and 29 therapists). Results: Neither clients' race/ethnicity, therapists’ race/ethnicity, nor client‐therapist ethnic matching predicted perceptions of microaggressions. Clients' ratings of microaggressions were negatively associated with their psychological wellbeing; however, this effect was mediated by clients' ratings of the working alliance. Implications: Therapists should take into account the cultural messages they may be conveying to both white and racial/ethnic minority clients. Therapists should develop strategies that are consistent with a general therapeutic approach that promotes discussions about culture with their clients and, most importantly, should attend to the therapeutic relationship.  相似文献   
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Previous research has shown that sounds facilitate perception of visual patterns appearing immediately after the sound but impair perception of patterns appearing after some delay. Here we examined the spatial gradient of the fast crossmodal facilitation effect and the slow inhibition effect in order to test whether they reflect separate mechanisms. We found that crossmodal facilitation is only observed at visual field locations overlapping with the sound, whereas crossmodal inhibition affects the whole hemifield. Furthermore, we tested whether multisensory perceptual learning with misaligned audio-visual stimuli reshapes crossmodal facilitation and inhibition. We found that training shifts crossmodal facilitation towards the trained location without changing its range. By contrast, training narrows the range of inhibition without shifting its position. Our results suggest that crossmodal facilitation and inhibition reflect separate mechanisms that can both be reshaped by multisensory experience even in adult humans. Multisensory links seem to be more plastic than previously thought.  相似文献   
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