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Many questions remain concerning whether, when, and how physicians order genetic tests, and what factors are involved in their decisions. We surveyed 220 internists from two academic medical centers about their utilization of genetic testing. Rates of genetic utilizations varied widely by disease. Respondents were most likely to have ordered tests for Factor V Leiden (16.8 %), followed by Breast/Ovarian Cancer (15.0 %). In the past 6 months, 65 % had counseled patients on genetic issues, 44 % had ordered genetic tests, 38.5 % had referred patients to a genetic counselor or geneticist, and 27.5 % had received ads from commercial labs for genetic testing. Only 4.5 % had tried to hide or disguise genetic information, and <2 % have had patients report genetic discrimination. Only 53.4 % knew of a geneticist/genetic counselor to whom to refer patients. Most rated their knowledge as very/somewhat poor concerning genetics (73.7 %) and guidelines for genetic testing (87.1 %). Most felt needs for more training on when to order tests (79 %), and how to counsel patients (82 %), interpret results (77.3 %), and maintain privacy (80.6 %). Physicians were more likely to have ordered a genetic test if patients inquired about genetic testing (p?<?.001), and if physicians had a geneticist/genetic counselor to whom to refer patients (p?<?.002), had referred patients to a geneticist/genetic counselor in the past 6 months, had more comfort counseling patients about testing (p?<?.019), counseled patients about genetics, larger practices (p?<?.032), fewer African-American patients (p?<?.027), and patients who had reported genetic discrimination (p?<?.044). In a multiple logistic regression, ordering a genetic test was associated with patients inquiring about testing, having referred patients to a geneticist/genetic counselor and knowing how to order tests. These data suggest that physicians recognize their knowledge deficits, and are interested in training. These findings have important implications for future medical practice, research, and education.  相似文献   
113.
Several neurological control strategies for fast head movements are considered using computer simulations of a stretch reflex model. Each control strategy incorporates a different amount of proprioceptive feedback contributing to braking and/or clamping the movement. The model behavior for each control strategy is qualitatively compared to experimental data that includes the agonist and antagonist EMGs, and the head position, velocity, and acceleration. Significance of the study is discussed with respect to the characteristic tri-phasic EMG pattern for fast voluntary movements and the possible roles that the stretch reflex may have in contributing to this pattern of activation.  相似文献   
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Openness to Experience is an important but relatively poorly understood personality construct. Advances in openness research require further construct clarification as well as establishment of a common framework for conceptualizing and measuring the lower level structure of the construct. In this article, we present data from 3 studies to address this research need. In Study 1, we identify 6 facets of Openness to Experience—intellectual efficiency, ingenuity, curiosity, aesthetics, tolerance, and depthbased on a factor analysis of 36 existing Openness-related scales. In Study 2, we present further validity evidence for the 6-facet structure based on a newly developed measure of Openness. Data from this study also suggest the presence of 2 intermediate-level factors (i.e., aspects) of Openness: intellect and culture. In Study 3, we present a short form of the newly developed measure, retaining items that showed the highest internal consistency and measurement invariance across 3 samples: U.S. undergraduates, Chinese MBA students, and Chinese undergraduates. Together these 3 studies offer a more nuanced understanding of the multifaceted nature of the Openness construct.  相似文献   
116.
To illustrate the importance of facet-level investigations in predicting organizational outcomes and the need for more primary studies on this topic, we conducted a meta-analysis that took an exploratory look at differential relationships among 7 organizational criteria and Openness traits varying in breadth. Nine Openness predictors—the global dimension, 2 aspects (intellect and culture), and 6 facets (intellectual efficiency, ingenuity, curiosity, aesthetics, tolerance, and depth)—were examined in relations with various organizational criteria such as traditional performance outcomes (task performance, contextual performance, counterproductive work behavior), turnover, leadership effectiveness, training performance, and adaptive performance. Our results support the idea that Openness facets could exhibit differential validity for many organizational outcomes.  相似文献   
117.
Brown and Murphy's (1989) three-stage paradigm (generation, recall-own, generate-new) was used to assess the effects of participant elaboration on rates of unconscious plagiarism in two experiments using a creative task. Following the generation phase, participants imagined and rated a quarter of the ideas (imagery elaboration), generated improvements to another quarter (generative elaboration), and listened to a quarter of the ideas again without elaboration, with the remaining ideas acting as control. A week later, participants attempted to recall their own ideas, and generate new solutions to the same cues. In Experiment 1 both forms of elaboration equally increased correct recall, and decreased plagiarism in the generate-new task. However, generative elaboration led to significantly greater plagiarism in the recall-own task, but imagery elaboration did not. Participants in Experiment 2 were encouraged not to plagiarise by means of a financial incentive. However, they showed the same pattern as seen in Experiment 1. Therefore, contrary to a simple strength account, the probability of a person plagiarising another's ideas is linked to the particular nature of the elaboration carried out on that idea, rather than its familiarity.  相似文献   
118.
We attempted to differentiate the family environments of youth with Conduct Disorder (CD) compared to youth with a depressive disorder. Participants were 34 adolescents from a residential treatment facility. The K-SADS-P was used to determine the youth's diagnosis, while their family environment was assessed by the Self Report Measure of Family Functioning Child Version. A MANOVA was used to compare the two diagnostic groups on seven family environment variables. Results indicate that adolescents with CD described their parents as having a permissive and ambiguous discipline style, while adolescents with a depressive disorder described their relationship with their parents as enmeshed. A discriminant function analysis, using the two family environment variables of enmeshment and laissez-faire family style as predictors, correctly classified 82% of the participants. Implications for treatment of youth with both types of diagnoses and their families are discussed.  相似文献   
119.
This study assessed the psychosocial factors associated with contraceptive use among inner-city women at risk for HIV/STDs by using the transtheoretical model of behavior change. The five-city study group of women aged 15 to 34 years was recruited from neighborhoods, social service agencies and shelters ( n = 998). We measured stages of change for contraceptive use and assessed theoretically proposed factors associated with being at a higher stage. Variables such as perceived advantages of contraceptive use and normative support for use were very important at early stages, but less important in later stages. However, self-efficacy was important in both early (OR =1.5) and later (OR = 1.6) stages, suggesting that women's confidence in their ability to initiate and sustain contraceptive use is crucial.  相似文献   
120.
This study examines whether negative contact with immigrants promotes voting for radical right‐wing parties, to what extent this relationship can be explained by feelings of outgroup threat, and whether this relationship depends on perceived personal and collective self‐efficacy. Hypotheses were tested among 630 native Dutch respondents, mainly living in multicultural neighborhoods. The results show that negative contact with immigrants is associated with feelings of personal (egocentric) and group (sociotropic) threat, and both these feelings, in turn, are associated with radical right‐wing voting. However, negative intergroup contact is less strongly related to egocentric threat when individuals feel able to personally address negative situations with other people (personal self‐efficacy). Furthermore, the findings suggest that negative intergroup contact is less strongly related to sociotropic threat when individuals believe that people in their neighborhood are able to collectively address some negative situations (collective self‐efficacy).  相似文献   
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