Structural Equation Modeling Approaches for Analyzing Partially Nested Data

Study designs involving clustering in some study arms, but not all study arms, are common in clinical treatment-outcome and educational settings. For instance, in a treatment arm, persons may be nested in therapy groups, whereas in a control arm there are no groups. Methodological approaches for handling such partially nested designs have recently been developed in a multilevel modeling framework (MLM-PN) and have proved very useful. We introduce two alternative structural equation modeling (SEM) approaches for analyzing partially nested data: a multivariate single-level SEM (SSEM-PN) and a multiple-arm multilevel SEM (MSEM-PN). We show how SSEM-PN and MSEM-PN can produce results equivalent to existing MLM-PNs and can be extended to flexibly accommodate several modeling features that are difficult or impossible to handle in MLM-PNs. For instance, using an SSEM-PN or MSEM-PN, it is possible to specify complex structural models involving cluster-level outcomes, obtain absolute model fit, decompose person-level predictor effects in the treatment arm using latent cluster means, and include traditional factors as predictors/outcomes. Importantly, implementation of such features for partially nested designs differs from that for fully nested designs. An empirical example involving a partially nested depression intervention combines several of these features in an analysis of interest for treatment-outcome studies.     

Control of Multimovement Coordination

The present paper provides some hypotheses concerning the role of sensorimotor mechanisms in the coordination and programming of multimovement behaviors. The primary database is from experiments on the control of speech, a motor behavior that inherently requires multimovement coordination. From these data, it appears that coordination may be implemented by calibrated, sensorimotor actions which couple multiple movements for the accomplishment of common functional goals. The data from speech and select observations in other motor systems also reveal that these sensorimotor linkages are task-dependent and may underlie the intermovement motor equivalence that characterizes many natural motor behaviors. In this context, it is hypothesized also that motor learning may involve the calibration of these intermovement sensorimotor actions. These observations in turn provide some alternative perspectives on the concept of a motor program, primarily suggesting that individual movements and muscle contractions are not wholly prespecified, but shaped by sensorimotor adjustments.     

THERAPIST DEFENSIVENESS AND MARITAL THERAPY PROCESS AND OUTCOME

Abstract

This study examined the effect of couple socioeconomic status (SES); pretherapy marital adjustment; and therapist, husband, and wife defensiveness during the third session of marital therapy on posttherapy marital adjustment. Participants were 22 therapists and 88 couples. Each therapist treated 4 couples, 2 from the middle SES level and 2 from the lower SES level. Path analyses revealed that for husbands higher marital satisfaction before therapy was associated with higher adjustment at the end of therapy, but defensive therapist behavior during therapy was associated with lower posttherapy adjustment. A similar pattern was found for wives, but this should be interpreted with caution owing to potential dependencies in the wives' posttherapy adjustment scores. Neither SES nor pretherapy adjustment predicted therapist defensive behavior in therapy, and SES did not predict marital therapy outcome variance. Results suggest that therapist defensive behavior may reflect a style or characteristic of some marital therapists.     

Analyzing the convergent and discriminant validity of states and traits: development and applications of multimethod latent state-trait models

The analysis of convergent and discriminant validity is an integral part of the construct validation process. Models for analyzing the convergent and discriminant validity have typically been developed for cross-sectional data. There exist, however, only a few approaches for longitudinal data that can be applied for analyzing the construct validity of fluctuating states. In this article, the authors show how models of latent state-trait theory can be combined with models of multitrait-multimethod analysis to develop a model that allows for analyzing convergent and discriminant validity in time: the multimethod latent state-trait model. The model allows for identifying different sources of variance (trait consistency, trait-method specificity, occasion-specific consistency, occasion-specific method specificity, and unreliability). It is applied to the repeated measurement of depression and anxiety in children, which was assessed by self and teacher reports (N = 375). The application shows that the proposed models fit the data well and allow a deeper understanding of method effects in clinical assessment.     

Increasing CREB in the auditory thalamus enhances memory and generalization of auditory conditioned fear

Although the lateral nucleus of the amygdala (LA) is essential for conditioned auditory fear memory, an emerging theme is that plasticity in multiple brain regions contributes to fear memory formation. The LA receives direct projections from the auditory thalamus, specifically the medial division of the medial geniculate nucleus (MGm) and adjacent posterior intralaminar nucleus (PIN). While traditionally viewed as a simple relay structure, mounting evidence implicates the thalamus in diverse cognitive processes. We investigated the role of plasticity in the MGm/PIN in auditory fear memory. First we found that auditory fear conditioning (but not control manipulations) increased the levels of activated CREB in both the MGm and PIN. Next, using viral vectors, we showed that exogenously increasing CREB in this region specifically enhanced formation of an auditory conditioned fear memory without affecting expression of an auditory fear memory, formation of a contextual fear memory, or basic auditory processing. Interestingly, mice with increased CREB levels in the MGm/PIN also showed broad auditory fear generalization (in contrast to control mice, they exhibited fear responses to tones of other frequencies). Together, these results implicate CREB-mediated plasticity in the MGm/PIN in both the formation and generalization of conditioned auditory fear memory. Not only do these findings refine our knowledge of the circuitry underlying fear memory but they also provide novel insights into the neural substrates that govern the degree to which acquired fear of a tone generalizes to other tones.     

Affective mechanisms linking dysfunctional behavior to performance in work teams: a moderated mediation study

The present study examines the association between dysfunctional team behavior and team performance. Data included measures of teams' dysfunctional behavior and negative affective tone as well as supervisors' ratings of teams' (nonverbal) negative emotional expressivity and performance. Utilizing a field sample of 61 work teams, the authors tested the proposed relationships with robust data analytic techniques. Results were consistent with the hypothesized conceptual scheme, in that negative team affective tone mediated the relationship between dysfunctional team behavior and performance when teams' nonverbal negative expressivity was high but not when nonverbal expressivity was low. On the basis of the findings, the authors conclude that the connection between dysfunctional behavior and performance in team situations is more complex than was previously believed--thereby yielding a pattern of moderated mediation. In sum, the findings demonstrated that team members' collective emotions and emotional processing represent key mechanisms in determining how dysfunctional team behavior is associated with team performance.