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151.
Ramirez JJ Campbell D Poulton W Barton C Swails J Geghman K Courchesne SL Wentworth S 《Neurobiology of learning and memory》2007,87(2):264-268
Entorhinal cortex lesions induce significant reorganization of several homotypic and heterotypic inputs to the hippocampus. This investigation determined whether surviving heterotypic inputs after bilateral entorhinal lesions would support the acquisition of a learned alternation task. Rats with entorhinal lesions or sham operations were trained to acquire a spatial alternation task. Although the sham-operated rats acquired the task within about 3 weeks postsurgery, rats with bilateral entorhinal lesions failed to learn the task after 12 consecutive weeks of training despite heterotypic sprouting of the cholinergic septodentate pathway and the expansion of the commissural/associational fiber plexus within the dentate gyrus. Thus, heterotypic sprouting failed to ameliorate significantly the effects of bilateral entorhinal lesions. Rather, entorhinal lesions produced a persistent impairment of spatial memory, characterized by a mixture of random error production and perseverative responding. 相似文献
152.
Same-object bias occurs when tasks associated with processing a single object are faster than tasks associated with two objects. Over five experiments we assessed whether same-object bias is mediated by the collinearity of the targets. Participants decided whether two targets, presented either within a single object or across two objects, were the same or different. Results showed that same-object bias only occurred when targets appeared on the same straight line within the same object. When targets appeared in the same object but were separated by an angle or corner, within-object facilitation was eliminated or greatly reduced. In a final experiment, response times to two targets that were collinear but on separate objects were responded to faster than were noncollinear targets on the same object. This suggests that collinearity between targets mediates the effect found in this paradigm, at least to a greater extent than colour grouping. 相似文献
153.
Training and development are integral to organizational change but are difficult to accomplish effectively in dynamic and complex work environments. Such environments can lead to nonoptimal training conditions that reduce individuals' readiness to change and training effectiveness. On the basis of the transtheoretical model of change (J. O. Prochaska, C. C. DiClemente, & J. C. Norcross, 1992), the authors examined pretraining influences (choice, social support, and motivation to learn) on readiness to change under nonoptimal training conditions. They examined specific dimensions of readiness to change rather than a global readiness to change construct. Participants were 183 driving under the influence (DUI) offenders participating in a court-mandated, alcohol-related Weekend Intervention Program. Perceived choice to attend training, social support, and motivation to learn affected readiness to change when individuals were resisting, considering, acting on, or maintaining behavior or attitude change. These effects were also dependent on age. Results suggest how training effectiveness could be improved when trainees are least likely to learn. 相似文献
154.
Ron Cole‐Turner 《Zygon》2014,49(3):642-651
Entheogens or psychedelic drugs such as lysergic acid diethylamide (LSD) and psilocybin are associated with mystical states of experience. Drug laws currently limit research, but important new work is under way at major biomedical research facilities showing that entheogens reliably occasion mystical experiences and thereby allow research into brain states during these experiences. Are drug‐occasioned mystical experiences neurologically the same as more traditional mystical states? Are there phenomenological and theological differences? As this research goes forward and the public becomes more widely aware of its achievements, religious scholars and experts in science and religion will be called upon to interpret the philosophical and theological presuppositions that underpin this research and the significance of the findings that flow from it. 相似文献
155.
Vikram K. Jaswal Koraly Pérez‐Edgar Robyn L. Kondrad Carolyn M. Palmquist Caitlin A. Cole Claire E. Cole 《Developmental science》2014,17(6):965-976
Why are some young children consistently willing to believe what they are told even when it conflicts with first‐hand experience? In this study, we investigated the possibility that this deference reflects an inability to inhibit a prepotent response. Over the course of several trials, 2.5‐ to 3.5‐year‐olds (N = 58) heard an adult contradict their report of a simple event they had both witnessed, and children were asked to resolve this discrepancy. Those who repeatedly deferred to the adult's misleading testimony had more difficulty on an inhibitory control task involving spatial conflict than those who responded more skeptically. These results suggest that responding skeptically to testimony that conflicts with first‐hand experience may be challenging for some young children because it requires inhibiting a normally appropriate bias to believe testimony. 相似文献
156.
Sy-Miin Chow Jason J. Bendezú Pamela M. Cole Nilam Ram 《Multivariate behavioral research》2016,51(2-3):154-184
Several approaches exist for estimating the derivatives of observed data for model exploration purposes, including functional data analysis (FDA; Ramsay &; Silverman, 2005), generalized local linear approximation (GLLA; Boker, Deboeck, Edler, &; Peel, 2010), and generalized orthogonal local derivative approximation (GOLD; Deboeck, 2010). These derivative estimation procedures can be used in a two-stage process to fit mixed effects ordinary differential equation (ODE) models. While the performance and utility of these routines for estimating linear ODEs have been established, they have not yet been evaluated in the context of nonlinear ODEs with mixed effects. We compared properties of the GLLA and GOLD to an FDA-based two-stage approach denoted herein as functional ordinary differential equation with mixed effects (FODEmixed) in a Monte Carlo (MC) study using a nonlinear coupled oscillators model with mixed effects. Simulation results showed that overall, the FODEmixed outperformed both the GLLA and GOLD across all the embedding dimensions considered, but a novel use of a fourth-order GLLA approach combined with very high embedding dimensions yielded estimation results that almost paralleled those from the FODEmixed. We discuss the strengths and limitations of each approach and demonstrate how output from each stage of FODEmixed may be used to inform empirical modeling of young children’s self-regulation. 相似文献
157.
158.
Blake Victor Kent James C. Davidson Ying Zhang Kenneth I. Pargament Tyler J. VanderWeele Harold G. Koenig Lynn G. Underwood Neal Krause Alka M. Kanaya Shelley S. Tworoger Anna B. Schachter Shelley A. Cole Marcia O'Leary Yvette C. Cozier Martha L. Daviglus Aida L. Giachello Tracy Zacher Julie R. Palmer Alexandra E. Shields 《Journal for the scientific study of religion》2021,60(1):198-215
Social scientists have increasingly recognized the lack of diversity in survey research on American religion, resulting in a dearth of data on religion and spirituality (R/S) in understudied racial and ethnic groups. At the same time, epidemiological studies have increasingly diversified their racial and ethnic representation, but have collected few R/S measures to date. With a particular focus on American Indian and South Asian women (in addition to Blacks, Hispanic/Latinas, and white women), this study introduces a new effort among religion and epidemiology researchers, the Study on Stress, Spirituality, and Health. This multicohort study provides some of the first estimates of R/S beliefs and practices among American Indians and U.S. South Asians, and offers new insight into salient beliefs and practices of diverse racial/ethnic and religious communities. 相似文献
159.
Cole David R. Bradley Joff P. N. Lee Alex Taek-Gwang 《Studies in Philosophy and Education》2021,40(5):477-491
Studies in Philosophy and Education - In the South Korean film, The Parasite, the underling family, in an act of desperation, uses deceptive means to infiltrate the rich family. The term parasite... 相似文献
160.
Misty A.W. Hawkins Janna M. Colaizzi Ashley B. Cole Natalie G. Keirns Caitlin E. Smith Madison Stout John Chaney Manisha Sawhney David Gahn 《Behavior Therapy》2021,52(2):350-364
Acceptance-based behavioral therapies (ABTs) for obesity may be superior to standard behavioral therapies but have not been adequately tested with American Indians (AIs). Neurocognitive function is also unexamined in relation to behavioral weight loss among AIs despite findings that neurocognition predicts outcomes in general samples, may help explain some of the benefits of ABTs, and may be relevant to marginalized groups. The primary objective of this pilot was to examine the feasibility/acceptability of ABT in an AI sample. Exploratory analyses examined the relationship between neurocognition and weight loss. Forty-eight AI adults with overweight/obesity (ages 43.3 ± 10.3 years, 85% female; baseline body mass index = 36.8 ± 4.4 kg/m2) enrolled in a 6-month open ABT weight loss trial. Feasibility indices, including screening/enrollment, session attendance, retention rates for posttreatment assessments, and program acceptability were examined. Percent weight loss (%WL) was assessed as well as fluid and crystalized neurocognition (National Institutes of Health Toolbox Cognition Battery [NIHTB-CB]). We enrolled 79% of the eligible sample and retained 75% (N = 36) at posttreatment assessments. Program completers lost an average of 5.2 ± 4.9% of initial body weight (dz = 1.14), whereas intent-to-treat analyses show a mean loss of 4.1 ± 4.7%. Participants reported high satisfaction, effectiveness, and cultural appropriateness. Exploratory analyses of neurocognitive domains suggested that crystalized cognition was higher among completers, and higher baseline cognitive flexibility predicted greater %WL (β = .34, p = .05). ABT resulted in clinically significant weight loss in an AI sample. A controlled trial of ABT in a larger, more diverse sample is warranted to determine whether (a) the findings are robust, generalizable, and/or superior to other treatments and (b) neurocognitive factors moderate outcomes. 相似文献