Effects of acute psychosocial stress exposure on endocrine and affective reactivity in college students differing in the 5-HTTLPR genotype and trait neuroticism

Enhanced stress vulnerability has been implicated in the pathogenesis of affective disorders. Although both genetic (5-HTTLPR) and cognitive (neuroticism) factors are known to increase stress vulnerability, no experimental study has investigated the interaction between these two factors on psychobiological reactivity following acute stress exposure. This study used a balanced experimental design to examine the interaction between the 5-HTTLPR genotype and trait neuroticism in neuroendocrine and affective stress responses. From a large group of 771 students, 48 carriers of the short/short (S/S) allele and 48 carriers of the long/long (L/L) allele with the lowest and the highest neuroticism scores (77 females, 19 males; mean age?±?SD: 20.6?±?2 years) were selected and exposed to an acute psychosocial stressor. Mood was assessed before and after the stressor, and salivary cortisol concentrations were measured before and at 20, 30, and 60?min after stressor onset. Acute stress increased salivary cortisol concentration regardless of either 5-HTTLPR genotype or neuroticism, but it caused a less profound negative mood change in L/L compared to S/S-allele carriers with the lowest neuroticism scores. The 5-HTTLPR genotype influences affective reactivity to acute stress conditional upon neuroticism, improving resilience to acute stress in L/L-allele carriers if they do not already possess high cognitive-affective (neuroticism) vulnerability.     

The concept of leakage in threat assessment

Leakage in the context of threat assessment is the communication to a third party of an intent to do harm to a target. Third parties are usually other people, but the means of communication vary, and include letters, diaries, journals, blogs, videos on the internet, emails, voice mails, and other social media forms of transmission. Leakage is a type of warning behavior that typically infers a preoccupation with the target, and may signal the research, planning, and implementation of an attack. Nomothetic data suggest that leakage occurs in a majority of cases of attacks on and assassinations of public figures, adult mass murders, adolescent mass murders, and school or campus shootings: very low-frequency, but catastrophic acts of intended and targeted violence. Idiographic or case data illustrate the various permutations of leakage. We discuss the operational importance of the concept, place it in the context of other warning behaviors, emphasize the need for further research, and outline risk management strategies for the mitigation of such acts of violence in both law enforcement and clinical mental health settings.     

Intraclass correlation associated with therapists: estimates and applications in planning psychotherapy research

It is essential that outcome research permit clear conclusions to be drawn about the efficacy of interventions. The common practice of nesting therapists within conditions can pose important methodological challenges that affect interpretation, particularly if the study is not powered to account for the nested design. An obstacle to the optimal design of these studies is the lack of data about the intraclass correlation coefficient (ICC), which measures the statistical dependencies introduced by nesting. To begin the development of a public database of ICC estimates, the authors investigated ICCs for a variety outcomes reported in 20 psychotherapy outcome studies. The magnitude of the 495 ICC estimates varied widely across measures and studies. The authors provide recommendations regarding how to select and aggregate ICC estimates for power calculations and show how researchers can use ICC estimates to choose the number of patients and therapists that will optimize power. Attention to these recommendations will strengthen the validity of inferences drawn from psychotherapy studies that nest therapists within conditions.     

Downward spirals of body surveillance and weight/shape concern among African American and Caucasian college women

Within dominant American culture, females often learn to view themselves from an observer's perspective and to treat themselves as objects to be looked at (i.e., self-objectification), which can result in negative outcomes. Body surveillance (the indicator of self-objectification) has been found to predict concern with weight/shape in predominantly Caucasian samples, but research has not yet examined the potential reciprocal relations between body surveillance and weight/shape concern. Participants were 226 women attending a Midwestern university (70 self-identified as African American and 156 as Caucasian) who provided data at two time points, spaced about 5 months apart. Results revealed that downward spirals of body surveillance and weight/shape concern were apparent for the Caucasian but not the African American women. However, there was evidence that body surveillance helped account for change in weight/shape concern for the African American women.     

Some effort for some: further evidence that scalar implicatures are effortful

Under the assumption of the principle of cooperation (Grice, 1989), a statement such as "some eels are fish" is thought to be false since it contains less information than is considered sufficient. However, the statement is logically sound since the meaning of "some" is compatible with "all". Currently, the primary interpretation of such underinformative statements remains subject to debate. According to Levinson (2000), the pragmatic "some but not all" interpretation is the default interpretation, while others (e.g., Sperber & Wilson, 1995) argue that this pragmatic interpretation only comes to the fore when relevant within the context and is thus considered secondary to the logical "some and perhaps all" interpretation. In this study, three factors that may influence the answer pattern are studied: task load, working memory capacity, and repetition of the statements. In Experiment 1, we used a secondary task paradigm to manipulate the cognitive load under which a number of underinformative statements had to be judged. We observed that for participants with a rather limited working memory span it is harder to reach a pragmatic interpretation under cognitive load. In Experiment 2, we manipulated the repetition of the statements. We observed that with a higher number of filler statements, participants produced fewer consistent answer patterns. This study provides further evidence against the automaticity of the pragmatic interpretation: It shows that the pragmatic interpretation requires more cognitive effort than the logical interpretation and that increasing the number of filler statements inhibits the development of a response strategy.     

Influence of balance on oral-motor control of speech: a pilot investigation

In this exploratory study, the interaction between motor coordination for balance and oral-motor control for speech was investigated in 31 typical college-aged women, ages 20 to 29 years (M = 22.3, SD = 2.1), recruited through the local university. Since speech is dependent on the control and coordination of the subsystems of the speech production mechanism, it was hypothesized that a difficult balance task would interfere with speech motor control. Oral-motor control was measured by diadochokinesis while participants were in a nonchallenging balance position (floor standing) and a challenging balance position (balance disk on one leg). Results indicated that individuals compensated for speech rate while having to maintain their balance for the syllable repetitions. However, the number of syllables repeated was significantly fewer while on the balance disk. In addition, a correlational analysis indicated that history of speech therapy services was related to poorer balance screening score. Directions for future research are discussed.     

Attentional Performance in Children and Adolescents with Tic Disorder and Co-Occurring Attention-Deficit/Hyperactivity Disorder: New Insights from a 2 × 2 Factorial Design Study

The aim of the present study was to investigate the effect of both tic disorder (TD) and attention-deficit/hyperactivity disorder (ADHD) on attentional functions. N = 96 children and adolescents participated in the study, including n = 21 subjects with TD, n = 23 subjects with ADHD, n = 25 subjects with TD+ADHD, and n = 27 controls. Attentional performance was tested based on four computerized attention tasks (sustained attention, divided attention, go/nogo and set shifting). The effect of TD as well as ADHD on attentional performance was tested using a 2 × 2 factorial approach. A diagnosis of TD had no negative impact on attentional functions but was associated with improved performance in the set shifting task. By contrast, regardless of a diagnosis of TD, subjects with ADHD were found to perform worse in the sustained attention, divided attention and go/nogo task. No interaction effect between the factors TD and ADHD was revealed for any of the attention measures. Our results add to findings from other areas of research, showing that in subjects with TD and ADHD, ADHD psychopathology is often the main source of impairment, whereas a diagnosis of TD has little or no impact on neuropsychological performance in most cases and even seems to be associated with adaptive mechanisms.     

The Mentoring Relationship Challenges Scale: The impact of mentoring stage, type, and gender

The current study investigated the role of relational challenges as reported by 309 protégés in various stages and types of mentoring relationships. The Mentoring Relationship Challenges Scale (MRCS) was newly constructed using the results of an earlier qualitative study (Ensher & Murphy, 2005). The scale measured three factors of relational challenges which were: Demonstrating Commitment and Resilience, Measuring Up to a Mentor's Standards, and Career Goal and Risk Orientation. The results demonstrated that with respect to mentoring stages, those protégés in the beginning stages of their relationships reported experiencing significantly fewer challenges related to Demonstrating Commitment and Resilience than those in the mature or ending stages of the relationship. Also, it was found that the type of mentoring relationship (traditional, step-ahead, or peer) affected the prevalence of the three types of challenges. Protégés in peer relationships reported significantly fewer of all three types of challenges than those in step-ahead or traditional relationships. However, contrary to predictions, there were no significant differences found between those in informal versus those in formal mentoring relationships. As expected, protégé and mentor gender interacted significantly. Female protégés reported experiencing significantly fewer challenges related to the factor of Measuring Up to a Mentor's Standards, than did male protégés. Also, female protégés reported experiencing a significantly higher degree of relational challenges related to Career Goal and Risk Orientation from their male mentors than from their female mentors. Finally, after controlling for perceptions of career and psychosocial support for protégés in traditional mentoring relationships, two of the three relational challenges factors remained significant and explained a significant amount of variance in overall satisfaction with the mentoring relationship. This suggests that relational challenges, at least for traditional mentoring relationships, serve as an important mechanism to impact overall relationship satisfaction.     

Coordination of executive functions in monolingual and bilingual children

Two groups of 8-year-old children who were monolingual or bilingual completed a complex classification task in which they made semantic judgments on stimuli that were presented either visually or auditorily. The task requires coordinating a variety of executive control components, specifically working memory, inhibition, and shifting. When each of the visual and auditory tasks was presented alone, performance was comparable for children in the two groups. Combining the two modalities into a dual-task paradigm made the task more difficult, and on this combined task bilingual children maintained better accuracy than monolingual children, especially on the visual task. The results are interpreted in terms of the enhanced ability of bilingual children to coordinate the executive control components required in performing this complex task.     

A psychometric study of the Drug Use Disorders Identification Test-Extended in a Norwegian sample

Motivation is a widely used concept in substance use treatment, and is commonly seen as a premise for change during treatment. Different measures of motivation have been suggested. A relatively new instrument is the Drug Use Disorders Identification Test-Extended (DUDIT-E), developed in Sweden. This instrument has recently been introduced in Norway. The present study examined the Motivational Index of the Norwegian version of the Drug Use Disorders Identification Test-Extended (DUDIT-E). We tested whether the three-factor model ("Positive aspects of substance abuse"; "Negative aspects of substance abuse"; and "Treatment readiness") suggested by previous studies could be replicated in a sample of Norwegian inpatients. Responses to the DUDIT-E were obtained from 105 patients admitted to inpatient substance abuse treatment in Northern Norway. Exploratory common factor analyses were used to compare the factor structure from the current sample with the Swedish sample of mainly detoxification patients and prison inmates. The current sample did not include prison inmates, and it consisted of more women than the Swedish sample. The samples did not differ according to age or substance dependency. The analyses suggested that six primary factors was the most efficient way of combining the item scores, and not 11 as in the Swedish sample. A second-order factor analysis found best support for a two-factor solution, and hence, did not replicate the previously suggested three-factor model either. Several regression analyses comparing the efficiency of the different ways of combining the DUDIT scores in primary or secondary factor scores indicated that the model involving six sum scores had best merit and should be explored further.