Neural mechanisms of affective interference in schizotypy

Negatively valenced stimuli foster cognitive impairment in schizotypy and schizophrenia. To identify relevant brain mechanisms, the authors had 16 positive-schizotypy and 16 control participants perform an emotional Stroop task, judging the ink color of negative and neutral words during functional magnetic resonance imaging (fMRI) of regional brain activity. Schizotypy individuals showed increased right and decreased left activity in dorsolateral prefrontal cortex, indicating a deficit in maintenance of attentional set in the presence of negative emotional distractors. They also showed abnormal activity in ventral limbic areas, including decreased activity in nucleus accumbens and increased activity in hippocampus and amygdala, a circuit involved in the integration of cognitive and affective processes. These results indicate that aspects of emotion-cognition processes and the brain mechanisms that implement them are similar in schizotypy and schizophrenia.     

Personality correlates of heroic rescue during the holocaust

This study investigated the extent to which personality variables can be used to discriminate non-Jewish heroes of the Holocaust from bystanders and from a comparison group of prewar European immigrants who left their countries of origin prior to World War II. Eighty verified rescuers, 73 bystanders, and 43 immigrants were administered measures of locus of control, autonomy, risk taking, social responsibility, tolerance/authoritarianism, empathy, and altruistic moral reasoning. A three-group discriminant function analysis was able to correctly classify 80.2% of the sample by a combination of personality and demographic variables. When the bystanders and immigrants, who differed very little from each other, were grouped together and compared to the rescuers, the personality variables alone correctly classified 93.1% of the sample. Implications regarding the relationship between personality and altruistic behavior, as well as suggestions for future research are discussed.     

Bioethics and Christian Theology

The authors of this essay suggest that the field of bioethics and Christian theology have a great deal to offer to each other. The authors first argue that representatives from both fields must first make sure that they fully and correctly represent their respective position. In other words, scientists, ethicists, and theologians alike must make sure that they present their fields and not use their knowledge merely for personal gain at the stake of misguiding people. Once this is established, the authors then proceed to show the intimate relationship between Christianity and medicine that has existed throughout the ages. It is a call for a continuation of such a relationship that the authors suggest between bioethics and theology. Through an integration of bioethics and Christian theology, both scientists/physicians and theologians are able to gain greater insight into the human person—a focus in both fields.     

Concordant Spiritual Orientations as a Factor in Physician--Patient Spiritual Discussions: A Qualitative Study

Objectives: To understand the impact of physicians and patients religious/spiritual orientation on discussions of spiritual issues. Methods: We performed semi-structured interviews of 10 Missouri family physicians and 10 patients of these physicians, selecting subjects nonrandomly to represent a range of demographic factors, practice types, and chronic or terminal illness. We coded and evaluated transcribed interviews for themes. Results: Respondents expressed that similar belief systems facilitate patient–physician spiritual interactions and bring confidence to their relationships. Those holding dissimilar faiths noted limited ability to address spiritual questions directly. They cited significant barriers to spiritual interaction but considered that ecumenism, use of patient-centered care, and negotiation skills lessen these barriers. Conclusions: Our respondents view spirituality similarly to other aspects of the physician–patient relationship involving differing viewpoints. Where discordance exists, cross-cultural, patient-centered, diplomatic approaches facilitate spiritual discussions.     

From <Emphasis Type="Italic">Pintele Yid to Racenjude</Emphasis>: Chaim Zhitlovsky and racial conceptions of Jewishness

The Russian Jewish intellectual, Chaim Zhitlovsky (1865–1943), a leading architect of secular Jewish culture and thought, was a central figure in the progressive Jewish intelligentsia of the late nineteenth and early twentieth century. In an essay written in 1927, Yidn un Yiddishkayt (Jews and Jewishness), he sought to define the secular essence of what he calls Yiddishkayt. This essay is not the first in Zhitlovskys long publicistic career in which he searches for new, secular definitions of Jewish identity and culture. But this essay differs, since it is marked by Zhitlovskys use of contemporary social scientific notions of race and racial traits to conceptualize what he believes constitutes Jewishness in a non-religious context, along with his adoption of the mystical Jewish concept of the pintele yid, the theory of an innate Jewishness embodied by a Jewish spark. Zhitlovskys desire to craft a truly secular theory of Jewish identity led him ironically to accept models of Jewish identity at odds with his stated larger vision. In turning to contemporary racial theory, as well as long nurtured mystical models of Yiddishkayt, Zhitlovsky reveals the wide range of ideological discourses that led him to innovative and controversial notions of modern Jewish identity.     

The look of love: gaze shifts and person perception

Gaze direction is a vital communicative channel through which people transmit information to each other. By signaling the locus of social attention, gaze cues convey information about the relative importance of objects, including other people, in the environment. For the most part, this information is communicated via patterns of gaze direction, with gaze shifts signaling changes in the objects of attention. Noting the relevance of gaze cues in social cognition, we speculated that gaze shifts may modulate people's evaluations of others. We investigated this possibility by asking participants to judge the likability (Experiment 1) and physical attractiveness (Experiment 2) of targets displaying gaze shifts indicative of attentional engagement or disengagement with the participants. As expected, person evaluation was moderated by the direction of gaze shifts, but only when the judgment under consideration was relevant to participants. We consider how and when gaze shifts may modulate person perception and its associated behavioral products.     

Differences in Individual Approaches: Communication in the Familial Breast Cancer Consultation and the Effect on Patient Outcomes

This multicenter study aimed to assess (i) whether individual clinical geneticists and genetic counselors vary in their communication skills and (ii) whether this variation in communication impacts on patient outcomes, such as anxiety, depression, genetics knowledge, and satisfaction. One hundred and fifty women from high-risk breast cancer families attending their first genetic counseling consultation completed pre and post-consultation self-report questionnaires. The consultations were audiotaped and transcribed verbatim. Univariate analyses showed highly significant differences between individual clinical geneticists and genetic counselors in: facilitating understanding (p 0.001); facilitating active involvement (p 0.001); facilitating partnership building (p = 0.003); addressing emotional concerns (p 0.001); and discussing prophylactic mastectomy (p = 0.017). Multivariate linear regressions showed that this variation in communication resulted in a greater change in patients depression 4 weeks after the counseling session (p = 0.017). These findings suggest clinical geneticists and genetic counselors have achieved some standardization in communicating information, but showed diversity in their facilitation skills. Communication skills may be a useful area to explore further in this field.     

Infants' enumeration of actions: numerical discrimination and its signature limits

Are abstract representations of number – representations that are independent of the particular type of entities that are enumerated – a product of human language or culture, or do they trace back to human infancy? To address this question, four experiments investigated whether human infants discriminate between sequences of actions (jumps of a puppet) on the basis of numerosity. At 6 months, infants successfully discriminated four‐ versus eight‐jump sequences, when the continuous variables of sequence duration, jump duration, jump rate, jump interval and duration, and extent of motion were controlled, and rhythm was eliminated. In contrast, infants failed to discriminate two‐ versus four‐jump sequences, suggesting that infants fail to form cardinal number representations of small numbers of actions. Infants also failed to discriminate between sequences of four versus six jumps at 6 months, and succeeded at 9 months, suggesting that infants’ number representations are imprecise and increase in precision with age. All of these findings agree with those of studies using visual–spatial arrays and auditory sequences, providing evidence that a single, abstract system of number representation is present and functional in infancy.     

An on-line task for contrasting auditory processing in the verbal and nonverbal domains and norms for younger and older adults

Contrasting linguistic and nonlinguistic processing has been of interest to many researchers with different scientific, theoretical, or clinical questions. However, previous work on this type of comparative analysis and experimentation has been limited. In particular, little is known about the differences and similarities between the perceptual, cognitive, and neural processing of nonverbal environmental sounds and that of speech sounds. With the aim of contrasting verbal and nonverbal processing in the auditory modality, we developed a new on-line measure that can be administered to subjects from different clinical, neurological, or sociocultural groups. This is an on-line task of sound to picture matching, in which the sounds are either environmental sounds or their linguistic equivalents and which is controlled for potential task and item confounds across the two sound types. Here, we describe the design and development of our measure and report norming data for healthy subjects from two different adult age groups: younger adults (18–24 years of age) and older adults (54–78 years of age). We also outline other populations to which the test has been or is being administered. In addition to the results reported here, the test can be useful to other researchers who are interested in systematically contrasting verbal and nonverbal auditory processing in other populations.     

The Relative Contribution of Sibling Deviance and Peer Deviance in the Prediction of Substance Use Across Middle Childhood

This study investigated the quality of sibling relationships and sibling deviancy in a sample of children at-risk for substance use and antisocial behavior. Based on a history of empirical and theoretical models suggesting strong associations between children's development in the context of relationships and the emergence of delinquency and drug use, this research extends previous efforts by including sibling relationships in this developmental model, linking siblings with later substance use. Sibling relationship quality as well as peer deviance were examined using a multirater, multimethod assessment procedure. We tested 3 constructs (deviancy, warmth, and conflict) related to sibling behavior. Only sibling deviance and peer deviance directly predicted substance use. When both sibling deviance and peer deviance were examined as predictors of changes in substance use over time, only sibling deviance was significant. Implications for the development of substance use behavior in middle childhood are discussed.