A Meta-Analysis of Cognitive Deficits in Adults with a Diagnosis of Schizophrenia

This review identified 1275 studies examining cognitive deficits in people with schizophrenia, published between 1990 and 2003. Data from 113 studies (4365 patients and 3429 controls) were combined in a meta-analysis carried out on the five cognitive domains of IQ, memory, language, executive function, and attention. Studies were excluded where they lacked a suitable control group or failed to present complete information. In all five cognitive domains, analysis indicated a consistent trend for patients to perform more poorly than healthy controls, with significant heterogeneity across studies. Sources of heterogeneity were analyzed and a need to ensure more appropriate composition of patient and control groups and to adopt a more refined and methodologically correct, hypothesis-driven approach was identified.     

Amygdala activation to sad pictures during high-field (4 tesla) functional magnetic resonance imaging

Fear-related processing in the amygdala has been well documented, but its role in signaling other emotions remains controversial. The authors recovered signal loss in the amygdala at high-field strength using an inward spiral pulse sequence and probed its response to pictures varying in their degree of portrayed sadness. These pictures were presented as intermittent task-irrelevant distractors during a concurrent visual oddball task. Relative to neutral distractors, sad distractors elicited greater activation along ventral brain regions, including the amygdala, fusiform gyrus, and inferior frontal gyrus. In contrast, oddball targets engaged dorsal sectors of frontal, parietal, and cingulate cortices. The amygdala's role in emotional evaluation thus extends to images of grief and despair as well as to those depicting violence and threat.     

Relationships between physical activity and motor skills in middle school children

The purpose of this study was to examine the relationships between physical activity measured as pedometer steps and performance on three motor skill tests. A secondary purpose was to determine if middle school children are meeting the recommendation for the number of daily steps. A sample (n =217) of 6th, 7th and 8th grade students participated. Each subject wore a Digi-Walker pedometer for three consecutive days. Subjects additionally recorded their pedometer steps in two 45 min.-physical education classes. There were strong significant correlations between daily steps taken by boys and girls, pedometer steps during physical education class and the AAHPERD Passing Test and the Bass Stick Balance. Similar correlations were weaker for the Side-Step Agility Test. Multivariate analysis of variance was utilized to examine variability of the three skills test by sex and year in school. Differences between students in Grades 7 and 8 on the AAHPERD Passing Test were significant. In addition, significant differences between daily pedometer steps and steps during physical education between Grades 6 and 7 were observed. Boys and girls had similar means on the AAHPERD Passing Test and Bass Stick Balance Test, but not on the Side-Step Agility Test. Scores on the three movement skills tested in this study were not strongly related to physical activity of the entire sample. Steps taken by middle school children appear not to be related to these measures of motor skills.     

Marital conflict and acculturation among Mexican American husbands and wives

This study examined the relationship between acculturation and multiple dimensions of marital conflict among Mexican American husbands and wives. Participants were 151 husbands and wives who were recruited from a health maintenance organization in northern California and individually interviewed. More acculturated husbands and wives engaged in less avoidance of conflict and were more expressive of their feelings in an argument. Husbands who were more acculturated reported more conflict concerning sex and consideration for the other. Bicultural and more acculturated husbands reported that their wives were more verbally and physically aggressive, compared with mono-Mexican husbands. The findings provide evidence that more acculturated husbands and wives are involved in more direct expressions of conflict in their marriages, compared with less acculturated husbands and wives.     

Temporal kinetics of prefrontal modulation of the extrastriate cortex during visual attention

Single-unit, event-related potential (ERP), and neuroimaging studies have implicated the prefrontal cortex (PFC) in top-down control of attention and working memory. We conducted an experiment in patients with unilateral PFC damage (n=8) to assess the temporal kinetics of PFC-extrastriate interactions during visual attention. Subjects alternated attention between the left and the right hemifields in successive runs while they detected target stimuli embedded in streams of repetitive task-irrelevant stimuli (standards). The design enabled us to examine tonic (spatial selection) and phasic (feature selection) PFC-extrastriate interactions. PFC damage impaired performance in the visual field contralateral to lesions, as manifested by both larger reaction times and error rates. Assessment of the extrastriate P1 ERP revealed that the PFC exerts a tonic (spatial selection) excitatory input to the ipsilateral extrastriate cortex as early as 100 msec post stimulus delivery. The PFC exerts a second phasic (feature selection) excitatory extrastriate modulation from 180 to 300 msec, as evidenced by reductions in selection negativity after damage. Finally, reductions of the N2 ERP to target stimuli supports the notion that the PFC exerts a third phasic (target selection) signal necessary for successful template matching during postselection analysis of target features. The results provide electrophysiological evidence of three distinct tonic and phasic PFC inputs to the extrastriate cortex in the initial few hundred milliseconds of stimulus processing. Damage to this network appears to underlie the pervasive deficits in attention observed in patients with prefrontal lesions.     

Career benefits associated with mentoring for protégeé: a meta-analysis

Meta-analysis was used to review and synthesize existing empirical research concerning the career benefits associated with mentoring for the protégé. Both objective (e.g., compensation) and subjective (e.g., career satisfaction) career outcomes were examined. Comparisons of mentored versus nonmemored groups were included, along with relationships between mentoring provided and outcomes. The findings were generally supportive of the benefits associated with mentoring, but effect sizes associated with objective outcomes were small. There was also some indication that the outcomes studied differed in the magnitude of their relationship with the type of mentoring provided (i.e. career or psychosocial).     

Numerical stroop effect

2 male and 2 female students from an undergraduate class in experimental psychology were participants in a numerical Stroop effect experiment. Mean age for the students was 19.5 yr., with a SD of 2.4. The Stroop effect was investigated with a numerical, as opposed to a color, task. The four conditions were Symbols (-, + + +, ===, ::, :::), versus Alphabetic Characters (C, AAA, DD, BBB, DDD), versus Matched Digits and Number of Digits (1, 4444, 333, 22, 4444), versus Mismatched Digits and Number of Digits (2, 1111, 444, 33, 3333). Participants took longer to count Mismatched Digits than Symbols or Alphabetic Characters (analogous to the color Stroop effect). Participants took longer to read Mismatched Digits than Alphabetic Characters (analogous to the color reverse Stroop effect). Participants took less time to read or count Matched Digits than Alphabetic Characters (facilitation effect).     

Self-control in rhesus macaques (Macaca mulatta): controlling for differential stimulus exposure

Previous research on self-control using macaques (Macaca fascicularis) showed these animals have a strong bias for a delayed, larger reinforcer (Self-control) over an immediate, smaller reinforcer (Impulsive). Typical studies of self-control have used a discrete trials methodology with a secondary discriminative stimulus during the delay periods. This results in a greater exposure to the stimulus representing the self-controlled option and may account for some of the early exclusive preference for self-control observed. The present experiment examined self-control bias in three rhesus macaques (Macaca mulatta) while controlling for differential durations of stimulus exposure. Subjects were presented stimuli via a computer monitor and made choices by touching the stimulus at which point both stimuli were removed for the delay periods. All three subjects displayed a nearly exclusive bias for the delayed, larger reinforcer self-control). These results are consistent with previous studies, despite the variations in methodology and species.     

Adult attachment and patterns of extradyadic involvement

Relationships between patterns of extradyadic involvement (EDI) and adult attachment were examined separately with undergraduates and community adults reporting prior EDI. Those with fearful or preoccupied styles reported more intimacy motivations for EDI, and undergraduates with these styles also reported more self-esteem motivations. Conversely, those with a dismissive style reported more autonomy motivations for EDI. Those with a fearful attachment style reported ambivalence about intimacy in the EDI. Fearful and preoccupied undergraduates and community males reported a more obsessive extradyadic relationship. However, dismissive individuals did not report more casual EDI. Gender effects also emerged, with females reporting more intimacy motivations than males, and undergraduate males reporting more casual EDI than undergraduate females. In the undergraduate sample, dismissive males had the most extradyadic partners over the prior 2 years relative to all other groups, and preoccupied females reported more partners than secure females. Clinical implications of these findings are discussed.