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To describe factors associated with preimplantation genetic diagnosis (PGD) decisions among Jewish Israeli BRCA1/2 carriers or spouses of a male carrier, we contacted all women who initiated PGD consultation for embryonic BRCA1/2 mutation detection at Sheba Medical Center, prior to March 2014. Applying a qualitative approach, we asked women to elaborate on the factors they considered in either opting for PGD or discontinuing the screening procedure. Participants were 18 Jewish Israeli women; 14 were carriers of one of the Ashkenazi founder mutations in BRCA1/2, and four were spouses of male mutation carriers, who underwent at least one cycle of PGD. Prior to seeking PGD, ten of the women had no children. At the time of the interview, all but three had at least one child. Three factors emerged as key motivators for PGD: having witnessed the disease in a close relative (n = 12); prior IVF treatment for infertility (n = 12); and having pre-existing frozen embryos (n = 6). Ten women withdrew from the PGD process due to clinical, logistical, and financial reasons. In conclusion, most women decided to withdraw from PGD instead of continuing until a successful conception was achieved. Those who opted for PGD attributed their discontinuation of further screening to the emotional burden that is greatly intensified by practical difficulties.  相似文献   
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Research on immigrant adaptation has been criticized for ignoring the perspective of migrant communities, for framing migrants within a binary categorization of insiders/outsiders, and for focusing on the traumatic aspect of migration. This paper addresses these criticisms, by using a narrative approach to study the adaptation processes of one community of Jewish migrants from Cochin in India to Israel, from a resilience perspective. The study incorporates participant observations and life-story interviews with this first generation of migrants. The preeminent theme running through the life stories was that of the reconciliation of contrasts. This theme is demonstrated through identified patterns, in the life of the community, of both integration and separation from the wider society. The findings highlight the significant role played by cultural influences in the adaptation process and the potential that exists for active learning and the building of bridges to the inner world of migrants.  相似文献   
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Zohar Eitan  Renee Timmers 《Cognition》2010,114(3):405-422
Though auditory pitch is customarily mapped in Western cultures onto spatial verticality (high–low), both anthropological reports and cognitive studies suggest that pitch may be mapped onto a wide variety of other domains. We collected a total number of 35 pitch mappings and investigated in four experiments how these mappings are used and structured. In particular, we inquired (1) how Western subjects apply Western and non-Western metaphors to “high” and “low” pitches, (2) whether mappings applied in an abstract conceptual task are similarly applied by listeners to actual music, (3) how mappings of spatial height relate to these pitch mappings, and (4) how mappings of “high” and “low” pitch associate with other dimensions, in particular quantity, size, intensity and valence. The results show strong agreement among Western participants in applying familiar and unfamiliar metaphors for pitch, in both an abstract, conceptual task (Exp. 1) and in a music listening task (Exp. 2), indicating that diverse cross-domain mappings for pitch exist latently besides the common verticality metaphor. Furthermore, limited overlap between mappings of spatial height and pitch height was found, suggesting that, the ubiquity of the verticality metaphor in Western usage notwithstanding, cross-domain pitch mappings are largely independent of that metaphor, and seem to be based upon other underlying dimensions. Part of the discrepancy between spatial height and pitch height is that, for pitch, “up” is not necessarily “more,” nor is it necessarily “good.” High pitch is only “more” for height, intensity and brightness. It is “less” for mass, size and quantity. We discuss implications of these findings for music and speech prosody, and their relevance to notions of embodied cognition and of cross-domain magnitude representation.  相似文献   
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Anchoring and adjustment comprise a heuristic that creates expectations. Two types of anchors were applied on participants' evaluation of products: the price reference of the product (maximum, minimum, or no price reference) and the context in which the products were evaluated (the prestige of the shopping center). Results showed that both factors anchored evaluations of products' value. Context effects were explained by the different expectations of visitors in prestigious (looking for quality) and less prestigious (seeking a bargain) centers.  相似文献   
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The effect of question repetition and variation on the efficiency of the Guilty Knowledge Test (GKT), based on electrodermal and respiration measures, was examined in a between-subjects experiment with 3 conditions. Each participant was presented with a sequence of 12 biographical questions. In Condition 1, a single question was repeated 12 times; in Condition 4, each of 4 different questions was repeated 3 times; and in Condition 12, 12 different questions were used. A monotonic relationship between the number of different questions used and detection efficiency was observed only with the electrodermal measure (the areas under the receiver operating characteristic curves, obtained with this measure in Conditions 1, 4, and 12 were .68, .81, and .99, respectively). These results demonstrate that a GKT based on multiple questions is superior to the use of many repetitions of a single or a few questions, and it can reach an almost perfect detection efficiency.  相似文献   
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The present study provides a first attempt to compare the validity of the respiration line length (RLL) and skin resistance response (SRR) amplitude in real-life criminal guilty knowledge tests (GKTs). GKT records of 40 innocent and 40 guilty Ss, for whom actual truth was established by confession, were assessed for their accuracy. When a predefined decision rule was used and inconclusive decisions were excluded, 97.4% of the innocent Ss and 53.3% of the guilty Ss were correctly classified with the SRR measure. For the RLL measure, the respective results were 97.2% and 53.1%. The combination of both measures improved detection of guilty Ss to 75.8% and decreased detection of innocent Ss to 94.1%. The combined measure seems to be a more useful means of identifying guilty suspects than each physiological measure alone. The results elaborate and extend those obtained in a previous field study conducted by Elaad (1990).  相似文献   
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People tend to overestimate their capacity to detect lying in others and to underestimate their own ability to tell lies. These biases were demonstrated in a sample of 60 police officers. In a lie‐detection task, the officers evaluated their accuracy as high and were overconfident in their judgements. In fact, their performance was below chance level. Participants also received false feedback about their performance. When the feedback suggested that they had performed better than they thought, this further enhanced their perceived lie‐detection capacity and also increased their belief in their ability to conceal their own lies. When the feedback suggested they had performed worse than they thought, their ratings of both lie detection and their lie‐telling abilities were lowered. Results are discussed in terms of anchoring, availability, and the self‐assessment bias. On a practical level, the tendency of police interrogators to overestimate their ability to detect deception could change suspicion into certainty and increase the risk of a false confession. Copyright © 2003 John Wiley & Sons, Ltd.  相似文献   
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