Controlling attention to gaze and arrows in childhood: an fMRI study of typical development and Autism Spectrum Disorders

Functional magnetic resonance imaging was used to examine functional anatomy of attention to social (eye gaze) and nonsocial (arrow) communicative stimuli in late childhood and in a disorder defined by atypical processing of social stimuli, Autism Spectrum Disorders (ASD). Children responded to a target word ('LEFT'/'RIGHT') in the context of a distracting arrow or averted gaze pointing in a direction that was congruent, incongruent, or neutral (bar without arrowheads, central gaze) relative to the target word. Despite being irrelevant to the target task, both arrow and averted gaze facilitated responses (Congruent vs. Neutral trials) to the same extent in the two groups and led to interference (Incongruent vs. Congruent trials), which was greater from arrows in ASD than control children. In the brain, interaction between group and distracter-domain was observed in frontal-temporal regions during facilitation and frontal-striatal regions during interference. During facilitation, regions associated with attention to gaze in control children (left superior temporal sulcus, premotor) were associated with attention to arrows in ASD children; gaze was associated with medial temporal involvement in ASD children. During interference, regions associated with arrows in control children (anterior cingulate, right caudate) were activated in response to gaze in ASD children; further, left dorsolateral prefrontal cortex, a region not observed in control children, was activated during gaze-interference in ASD children. Thus, functional anatomy was atypical in ASD children during spontaneous processing of social and nonsocial communicative cues.     

Naltrexone's effects on reactivity to alcohol cues among alcoholic men

The mechanisms of naltrexone's effects on urges to drink during abstinence are unclear. Naltrexone may suppress either urges to drink specifically or appetitive responses in general. The effects of naltrexone on cue reactivity to alcoholic and sweet nonalcoholic beverages were investigated. Alcohol-dependent men (N = 53) in treatment received naltrexone (50 mg) or placebo. Four hours later, they received baseline assessment, exposure to fruit juice, and exposure to their usual alcoholic beverage in 3-min trials. Naltrexone reduced urge to drink and self-reported attention to the alcohol cues, not at the initial exposure but after repeated exposures to alcohol cues. Naltrexone reduced negative affect across baseline and alcohol trials. No effects of naltrexone on responses to the nonalcoholic appetitive beverage cues were found, suggesting that general appetite suppression does not mediate the effects of naltrexone on urges.     

Category learning with minimal prior knowledge

In 6 experiments, the authors examined the use of prior knowledge in category learning. Previous studies of the effects of knowledge on category learning have used categories in which knowledge was related to all of the category's features. However, people's knowledge of real-world categories often consists of many "rote" features that are not related to their prior knowledge. Five experiments found that even minimal prior knowledge (1 knowledge-relevant feature and 5 rote features per exemplar) can facilitate category learning. Posttests revealed that although the knowledge aided learning, subjects also acquired the rote features that were not related to knowledge, contradicting predictions of an attentional explanation of the knowledge effect. The results of Experiment 6 suggested that subjects attempt to link even rote features to their knowledge.     

Tortured families: a Coordinated Management of Meaning analysis

Torture is known to affect both the individual and the family. The aim of the present study was to reach a better understanding of the significance of communication and information about parental exposure to violence in torture-surviving families. The theoretical background is Social Constructionism and Coordinated Management of Meaning (CMM). In-depth interviews were carried out with 14 members of 3 Middle Eastern refugee families living in Denmark in which the father had been exposed to torture. The 3 families experienced their life stories and situations as refugees in very different ways, ranging from meaninglessness, discontinuance, and alienation to a sense of community, solidarity, and openness. Communications about past events were related to such meaning-providing contexts. The way in which parents talk with their children about torture and organized violence can be understood in terms of "stories told" and "stories lived." When stories told (e.g., the experience of torture and organized violence) are in contradiction to stories lived, a situation of ambiguity and uncertainty is created. The meaning-providing contexts for making sense of the family history of violence and exile can be more or less coherent or contradictory, and might result in a strengthened relationship or confusion, powerlessness, and action paralysis. Clinicians can help traumatized families deal with their past histories of violence by paying attention to such ambiguities and contradictions.     

Traits and stories: links between dispositional and narrative features of personality

Dispositional traits and life narratives represent two different levels of personality that have not previously been empirically linked. The current study tested five hypotheses connecting Big-Five traits to life-narrative indices of emotional tone, theme, and structure. Students (Study 1) and adults (Study 2) completed a self-report measure of the Big-Five traits and provided extended written accounts of either ten (students) or eight (adults) key life-narrative scenes, including life high points, low points, and turning points. Content analysis of the narrative data revealed that for both samples Neuroticism was positively associated with an emotionally negative life-narrative tone, Agreeableness was correlated with narrative themes of communion (e.g., friendship, caring for others), and Openness was strongly associated with the structural complexity of life narrative accounts. Contrary to prediction, however, Conscientiousness was not consistently associated with themes of agency (e.g., achievement, self-mastery) and Extraversion was unrelated to positive narrative tone. The results are discussed in the context of contemporary research and theorizing on the narrative study of lives and the relation of narrative research in personality to more conventional, trait-based approaches.     

Relationships between physiological and psychological stress and salivary immunoglobulin A among young female gymnasts

We investigated whether psychological and physical stress induced by training or competition influence the secretory immune system among 12 highly trained young female gymnasts. Salivary levels of secretory IgA and cortisol responses to gymnastic training session or competition were assessed a total of 10 times, immediately before and after two training sessions which had different intensities and just before and after a major competition. These parameters were also measured on two non-training days. The Brunel Mood Scale was also used to assess the gymnasts's overall mood on each test day. IgA:Protein ratio was calculated. Significant decreases in this ratio were found after each exercise session, related to the physiological and psychological stress induced by exercise. Over the 5-mo. training period the presession IgA:Protein ratios were unchanged. Gymnasts registered any episodes of upper respiratory tract infection. Bouts of exercise induce transitory effects on the immune system in relation to the workload and the stress induced by the exercise without any relation to increased susceptibility to illness in children.     

Cross-serial dependencies in dutch: Testing the influence of NP type on processing load

We tested the cross-linguistic generalizability of three models of sentence processing complexity--Lewis (1996), Gibson (1998, 2000), and Gordon (Gordon, Hendrick, & Johnson, 2001; Gordon, Hendrick, & Levine, 2002)--by investigating the on-line processing of cross-serial dependencies in Dutch. The number of subject-verb relations in a clause was manipulated, as well as type of noun phrase (indexical pronouns vs. proper names or full definite NPs). Several of our findings diverged from Gibson's model: Processing difficulty at the verbs was not affected by the use of proper names versus first- and second-person pronouns; an increase at the first verb was seen for full NPs versus pronouns in 3-verb constructions, which was predicted by the Gibson model, but is in contrast to Lewis's model. These findings are best explained within the framework of similarity-based inference models (Gordon et al., 2001; Gordon et al., 2002), according to which the number of similar NPs affects processing difficulty at the point of retrieval, and not specifically their discourse status or syntactic function.