Granny, (don't) get your gun: competency issues in gun ownership by older adults

This article explores the possible risks associated with gun ownership by older adults. We summarize existing regulations on who may own firearms, especially with respect to age. We then present data on older gun owners and violence committed by older adults in general, followed by a discussion of gun violence perpetrated by gun owners whose functional and cognitive abilities have declined, perhaps as a result of dementia. For comparison purposes, we review regulations on driving among older adults, drawing parallels to gun ownership. The paper concludes with recommendations for ensuring the safety of older gun owners and others, balanced against citizens' right to bear arms, and with some directions for research.     

Nicotine Produces a Within-Subject Enhancement of Contextual Fear Conditioning in C57BL/6 Mice Independent of Sex

Nicotine enhances learning including contextual fear conditioning. The present study extends previous work on nicotine and conditioned fear to examine the nature of nicotine's enhancement of contextual fear conditioning and sex differences in contextual fear conditioning in C57BL/6 mice using a within-subjects design. Mice were trained by pairing of an auditory stimulus of 80 dB, 6 cps train of broad-band clicks conditioned stimulus (CS) with a 2 sec., 0.35 mA shock unconditioned stimulus (US). Twenty-four hours later mice were tested for freezing in the original context, and one hour later mice were retested in the same context. A 0.5 mg/kg dose of nicotine was given either for three conditions: (1) before training, testing, and retesting; (2) before training and retesting; and (3) before retesting only. The use of a within-subjects design allowed for testing if nicotine would produce state-dependent deficits in contextual fear conditioning. Nicotine did enhance contextual fear conditioning in the groups that received nicotine for both training and testing. Nicotine, however, did not alter freezing when given on training but not testing or testing but not training. No sex differences, however, existed for conditioning or for nicotine's effects on conditioning. These results suggest that nicotine enhanced acquisition and retrieval processes but did not produce state-dependent deficits when administered just for training or just for testing.     

A randomised wait list-controlled pre–post–follow-up trial of a gratitude diary with a distressed sample

In a randomised wait list-controlled trial with repeated measures pre-, post- and follow-up design, participants (N = 109) with a current self-reported diagnosis of an anxiety disorder and/or depression, took part in an internet-based study. After completing a three-week gratitude diary returning participants had lower scores on measures of depression, anxiety, stress and perceived sleep difficulties and higher scores on a measure of subjective well-being than immediately pre-intervention. At three-week follow-up depression and sleep scores for returning participants were no longer significantly different from pre-intervention, however, improvements for subjective well-being and stress at post-intervention were maintained. At follow-up anxiety scores had not only been maintained but had improved significantly beyond post-intervention results. Intention to treat analyses were conducted and provided support for most completer results. Differences between the two sets of analyses are discussed below. This trial provides support for the use of gratitude diaries as an intervention with distressed populations.     

Beyond positive or negative: variability in daily parent-adolescent interaction quality is associated with adolescent emotion dysregulation

Previous work on the contribution of family environments to adolescent emotion dysregulation has tended to focus on broad parenting characteristics (such as warmth); however, it is possible that day-to-day variability in parenting may also relate to emotion dysregulation. The current study sought to test whether inconsistency in the quality of daily parent-youth interactions related to multiple indices of emotion dysregulation in adolescents. Two-hundred-twenty-two adolescents (ages 13–16; 53% female) participated with one parent. Adolescents completed 14-days of diary reporting on the quality of interactions with their parent (negative/neutral/positive) and their emotion dysregulation experiences for each day. Analyses reveal that, beyond the effects of average interaction quality, adolescents with greater variability in the quality of their interactions with their parent reported greater average emotion dysregulation across the days of diary recording and demonstrated greater variability in their ratings of daily emotion dysregulation. Findings were not accounted for by parental warmth or hostility, parent-reported trait-level emotion regulation, or day-level associations between study variables. In these ways, greater variability – and not merely greater negativity – during interactions between parents and adolescents was related to adolescent emotion dysregulation, suggesting that consistency in parent–adolescent relationships may be an important dimension of psychosocial risk to consider within families.     

Intervention,stimulus control,and generalization effects of response interruption and redirection on motor stereotypy

This study evaluated the effects of response interruption and redirection (RIRD) on motor stereotypy (hand and body movements) in a child with neurodevelopmental disorders. We also assessed whether a stimulus paired with RIRD could acquire inhibitory control when tested during nonintervention conditions. Compared with baseline phases in a reversal design, RIRD decreased both hand and motor stereotypies, and there was evidence of stimulus control. Extending RIRD to a second setting was also effective. The care providers responsible for intervention implemented RIRD with fidelity, and they rated the procedure positively. Clinical and research implications from these findings are discussed.     

Just World Beliefs Are Associated With Lower Levels of Metabolic Risk and Inflammation and Better Sleep After an Unfair Event

This study's goal was to conduct a preliminary test of the theory that just world beliefs can buffer against negative physiological outcomes after people experience certain types of negative life events by testing associations between just world beliefs and physiological outcomes among people with different life event histories. In a sample of 247 adults (M_age = 46.01; 24.31% men; 60.78% White), this research investigated the relationship between just world beliefs and metabolic symptoms, inflammation, and sleep among people who had recently experienced an unfair event, another type of negative event, or no negative event. Stronger just world beliefs correlated with lower metabolic risk, lower inflammation, and better sleep among people who had recently experienced an unfair event, but not among those in the other two event groups. These findings suggest that people's beliefs about the world may interact with their life experiences in ways that have implications for health‐relevant outcomes.     

On the dissociation between reaction time and response duration as a function of lexical and sublexical reading: An examination of phonetic decoding and computational models

Neurobiological models of reading account for two ways in which orthography is converted to phonology: (1) familiar words, particularly those with exceptional spelling-sound mappings (e.g., shoe) access their whole-word lexical representations in the ventral visual stream, and (2) orthographically unfamiliar words, particularly those with regular spelling-sound mappings (i.e., pseudohomophones [PHs], which are orthographically novel but sound like real words; e.g., shue) are phonetically decoded via sublexical processing in the dorsal visual stream. The present study used a naming task in order to compare naming reaction time (RT) and response duration (RD) of exception and regular words to their PH counterparts. We replicated our earlier findings with words, and extended them to PH phonetic decoding by showing a similar effect on RT and RD of matched PHs. Given that the shorter RDs for exception words can be attributed to the benefit of whole-word processing in the orthographic word system, and the longer RTs for exception words to the conflict with phonetic decoding, our PH results demonstrate that phonetic decoding also involves top-down feedback from phonological lexical representations (e.g., activated by shue) to the orthographic representations of the corresponding correct word (e.g., shoe). Two computational models were tested for their ability to account for these effects: the DRC and the CDP+. The CDP+ fared best as it was capable of simulating both the regularity and stimulus type effect on RT for both word and PH identification, although not their over-additive interaction. Our results demonstrate that both lexical reading and phonetic decoding elicit a regularity dissociation between RT and RD that provides important constraints to all models of reading, and that phonetic decoding results in top-down feedback that bolsters the orthographic lexical reading process.     

Influences on communicative development at 24 months of age: child temperament, behaviour problems, and maternal factors

Within a longitudinal study using a large representative, community sample of infants recruited at mean age 8 months, we examined influences on infant communication development at 24 months, including child gender, shy temperament, behavioural and emotional problems, and several variables relating to maternal psychosocial health. On most developmental measures girls were in advance of boys and they also showed shyer temperament. Child gender, shy temperament and maternal psychosocial indices were associated with both vocabulary development as measured by the MacArthur-Bates Communicative Development Inventory (CDI), and communication and symbolic development assessed via the Communication and Symbolic Behaviour Scales-Developmental Profile (CSBS) at 24 months. No prediction was found using scores at 8 or 12 months, although moderate stability between measures between 12 and 24 months was evident. Predictors of 24 month outcomes were all concurrently measured variables, and included temperamental shyness, but very little variance in communication outcomes was explained. Children whose mothers were experiencing clinical levels of depression and life difficulties reported more child behavioural problems.     

Beta2 subunit containing acetylcholine receptors mediate nicotine withdrawal deficits in the acquisition of contextual fear conditioning

Acute nicotine enhances contextual fear conditioning, whereas withdrawal from chronic nicotine produces impairments. However, the nicotinic acetylcholine receptors (nAChR) that are involved in nicotine withdrawal deficits in contextual fear conditioning are unknown. The present study used genetic and pharmacological techniques to investigate the nAChR subtype(s) involved in the effects of nicotine withdrawal on contextual fear conditioning. beta2 or alpha 7 nAChR subunit knockout (KO) and corresponding wild-type (WT) mice were withdrawn from 12 days of chronic nicotine treatment (6.3mg/kg/day), and trained with 2 conditioned stimulus (CS; 85 dB white noise)--unconditioned stimulus (US; 0.57 mA footshock) pairings on day 13. On day 14, mice were tested for contextual and cued freezing. beta2 KO mice did not show nicotine withdrawal-related deficits in contextual fear conditioning, in contrast to WT mice and alpha 7 KO mice. A follow-up study investigated if nicotine withdrawal disrupts acquisition or recall of contextual fear conditioning. The high affinity nAChR antagonist dihydro-beta-erythroidine (DH beta E; 3mg/kg) was administered prior to training or testing to precipitate withdrawal in chronic nicotine-treated C57BL/6 mice. Deficits in contextual fear conditioning were observed in chronic nicotine-treated mice when DH beta E was administered prior to training, but not when administered at testing. These results indicate that beta2-containing nAChRs, such as the alpha 4 beta 2 receptor, mediate nicotine withdrawal deficits in contextual fear conditioning. In addition, nicotine withdrawal selectively affects acquisition but not recall or expression of the learned response.