Die Effekte psychoanalytisch orientierter und verhaltenstherapeutischer Langzeittherapien

This prospective study compares 31 patients in behavior long-term-therapy (with an average of 63 sessions) with 31 patients in psychoanalytically-oriented long-term-therapy (with an average of 185 sessions) in a naturalistic design. All patients passed a diagnostic interview (SKID) by an external interviewer. Only patients with depression and anxiety problems (Axis I of DSM III – R) were included in the study. Symptoms (SCL-90-R), interpersonal problems (IIP-D) and goals (GAS) were examined at the beginning, after 1 year, after 2.5 and 3.5 years. We found that the characteristics of patients, who choose – or were referred to – psychoanalytically oriented or behaviour long term therapy were different, even when their diagnosis were comparable, in a number of characteristics, such as education, access to psychotherapy (recommended by professionals versus patients introduce themselves), the taking of psychotropic medication, and the strain of symptoms. The results demonstrate how research comparing therapies using parallelized samples do not meet reality in every case: Even if psychoanalists and behavior therapists do treat equal disorders, – and they each do that very successfully, as we could prove – the patients differ in many ways. Effect sizes and clinically significant results about changes of the symptomatic and of interpersonal problems are presented that prove the efficacy of the treatments.     

EFFECTS OF REINFORCER QUALITY ON BEHAVIORAL MOMENTUM: COORDINATED APPLIED AND BASIC RESEARCH

The high-probability (high-p) instructional sequence has been an effective treatment for noncompliance. However, treatment failures have also been reported. We hypothesized that the efficacy of the high-p treatment may be improved by using higher quality reinforcers for compliance to high-p instructions. The resistance of compliance to change was tested by varying reinforcer quality in two applied studies and a basic laboratory experiment. Experiment 1 tested the hypothesis that an increase in reinforcer quality for high-p compliance will increase the effectiveness of the high-p treatment when it fails to increase compliance. Experiment 2 assessed the effects of reinforcer quality on resistance of compliance to change by presenting successive low-p requests following the high-p treatment. A basic laboratory study (Experiment 3) was conducted to further isolate the relation between reinforcer quality and behavioral momentum. Two different liquid reinforcers (sucrose and citric acid solutions) were presented in a two-component multiple variable-interval variable-interval schedule followed by a single extinction test session. Results of all three experiments showed a generally consistent relationship between reinforcer quality and behavioral momentum.     

Uncoupled leftward asymmetries for planum morphology and functional language processing

Explanations for left hemisphere language laterality have often focused on hemispheric structural asymmetry of the planum temporale. We examined the association between an index of language laterality and brain morphology in 99 normal adults whose degree of laterality was established using a functional MRI single-word comprehension task. The index of language laterality was derived from the difference in volume of activation between the left and right hemispheres. Planum temporale and brain volume measures were made using structural MRI scans, blind to the functional data. Although both planum temporale asymmetry (t(1,99) = 6.86, p < .001) and language laterality (t(1,99) = 15.26, p < .001) were significantly left hemisphere biased, there was not a significant association between these variables (r(99) = .01,ns). Brain volume, a control variable for the planum temporale analyses, was related to language laterality in a multiple regression (beta = -.30, t = -2.25, p < .05). Individuals with small brains were more likely to demonstrate strong left hemisphere language laterality. These results suggest that language laterality is a multidimensional construct with complex neurological origins.     

Effect of Sn on microstructure and mechanical properties of (Ti–Cu)-based bulk metallic glasses

A Ti₄₃Zr₇Cu₄₃Ni₇ bulk metallic glass (BMG) exhibits a plastic strain of less than 0.2% under room-temperature compression. However, a Ti₄₅Zr₅Cu₄₀Ni_7.5Sn_2.5 BMG developed by addition of Sn to Ti₄₃Zr₇Cu₄₃Ni₇ shows a significant improvement of ～14.8% to the plastic strain with work hardening. Microstructural comparison of these BMGs reveals that the addition of Sn leads to formation of nano-scale chemical heterogeneities throughout the material. These nano-scale chemical fluctuations play an important role in enhancing the plastic strain of (Ti–Cu)-based BMGs.     

Effect of sample size on ductility of metallic glass

With decreasing sample dimension, the compressive plastic strain of a Zr-based metallic glass increases from near zero to as high as 80% without failure. This indicates that macroscopically brittle or ductile deformation behaviour can occur in chemically and structurally identical metallic glass. A concept of critical shear offset is proposed to explain the strong size effect on the enhanced plasticity of metallic glass by taking the shear fracture energy density into account. This finding provides new understanding on the principle that for metallic glass ‘smaller is more ductile’, even on the macroscopic scale.     

Effect of crystallization on the surface area of porous Ni-based metallic glass foams

The change of the specific surface area in porous Ni₅₉Zr₂₀Ti₁₆Si₂Sn₃ metallic glass (MG) upon partial crystallization was investigated. The observed increase in the surface area of the annealed Ni-based MG foams is due to the formation of homogeneously distributed Ni₁₀(Zr,Ti)₇ rod-shape intermetallic phases with nominal diameters around 250?nm and ～800?nm length on the surface of MG struts during the crystallization. For longer annealing, the specific surface area decreases again due to a change of the morphology of the crystals from rod-like to disc-like appearance, thus suggesting an optimum regime for increasing the specific surface area upon isothermal annealing at a given temperature.     

Structural imaging in dyslexia: the planum temporale

The search for a neurobiological substrate for dyslexia has focused on anomalous planum symmetry. The results of imaging studies of the planum have been inconsistent, perhaps due to diagnostic uncertainty, technical differences in measurement criteria, and inadequate control of handedness, sex, and cognitive ability. Although structural imaging studies have not clarified the neurobiology of reading disability, converging evidence suggests that variation in asymmetry of the planum temporale does have functional significance. Studies in a variety of populations have shown a significant association between planar asymmetry, the strength of hand preference, and general verbal skills such as vocabulary and comprehension. Future structural imaging studies of dyslexia should match participants on hand preference and general verbal ability in order to determine the relationship between brain structure and written and oral language.