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The public do not like, and we do not like the idea of designer babies (Ruth Deech, then Chair of the Human Fertilisation and Embryology Authority, quoted in The Independent, 18 October 2000). We are all on the slippery slope-the question we should be asking is: skis or crampons (Professor John Harris, The Centre for Social Ethics and Policy, University of Manchester, in an interview with Susan Johnson). LINGUISTIC AND CULTURAL GROUNDING OF THE DESIGNER BABY DEBATE In October 2000, news was released of the world’s first ‘designer baby’—Adam Nash who was born on 29 August 2000 in the United States. He was chosen as a donor for his sister Molly, who suffered with Fanconi Anaemia, which is a rare genetic disease. Without a bone marrow transplant, Molly would have died before the age of 10. A suitable donor had not been found, so her parents decided to undergo in vitro fertilization (IVF), and preimplantation genetic diagnosis (PGD) to select an embryo that would not carry the disease-causing gene and would become a brother and a donor for Molly. At the time of his birth, Adam’s cord blood was collected and later transplanted into his sister. Initial reports suggest that the treatment has been successful.  相似文献   
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This research compares two contrasting perspectives of social contagion processes associated with the organizational outcome variables of commitment and role ambiguity in organizations. The two perspectives are structural equivalence (which focuses on the positions of individuals in social networks) and cohesion (which focuses on an individual's direct communication contacts). It was hypothesized that structural equivalence would be more associated with role ambiguity and that commitment would be more associated with cohesion. The relationship between these variables and multiplex content networks was also studied. It was hypothesized that commitment was a much more broadly based concept in the sense that a number of functional content networks systematically relate to it. On the other hand, role ambiguity was hypothesized to be more closely associated with uniplex networks, especially those related to job duties and organizational goals. While there were exceptions, generally the research results supported the hypotheses relating to multiplexity. The hypotheses that structural equivalence was more associated with role ambiguity and that commitment was more associated with cohesion also were supported in this research.  相似文献   
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Managers ’motives (preferences for different activities or outcomes) probably determine, in part, their relative job effectiveness. This hypothesis was tested and confirmed by Nash (1966) when he developed and cross-validated a Managerial Effectiveness Key for the 1937 edition of the Strong Vocational Interest Blank (SVIB). We revised the Nash SVIB key for those items retained in the recently-revised form of SVIB (Campbell, 1966). The new key has the same validity as Nash's key and high test-retest stability for lengthy periods of time (up to twenty-two years). Validity of the key is not extremely high (about .30), but its content does denote a pattern of stable and distinct manager motives which merit study along with cognitive, aptitude, and temperament factors as potential determiners of effective managing.  相似文献   
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Socially aggressive face threats (SAFTs) are messages that threaten one's identity or positive face. Given the potential negative consequences of being a recipient of such behavior, the role of positive face needs, intragroup status, and the face‐threatening nature of social aggression in predicting correlates of negative affect experienced as a result of being a target of SAFTs, including the face threat of the response, forgiveness, and well‐being was investigated. On the basis of the survey responses from 199 college‐aged women, findings indicated that targets' positive face needs and intragroup status are directly and indirectly associated with forgiveness and overall well‐being. Implications for these findings in relation to theorizing about face and intragroup identity, as well as limitations and suggestions for future research were provided.  相似文献   
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This article draws attention to Thomas Aquinas' under‐appreciated development of the doctrine of the atonement. I argue that Thomas' pursuit of the ‘fittingness’ of the passion yields an exceptional grasp of the multiplicity of effects accomplished by Christ's death. To defend this thesis, I explore the methodology underlying Thomas' approach to the atonement, contrasting it with that of Anselm. I then follow the implications of Thomas' methodology in his stance toward the diverse atonement theories of his day. In conclusion, I briefly note the significance of Thomas' method and conclusions for contemporary debates concerning the efficacy of Christ's passion.  相似文献   
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