An adjusting avoidance procedure with multiple auditory and visual warning stimuli

Male albino rats were trained on an adjusting avoidance schedule in which each lever press accumulated a given amount of shock-free time. Multiple auditory and visual stimuli were programmed for each discrete temporal distance from the shock in an effort to place the avoidance behavior under the control of the shock proximity. The effects of the stimuli were further examined by presenting part of them and then by removing them altogether. With the combined auditory and visual stimuli, the rat spent most of the time relatively close to the shock and usually started to respond only when the shock was near. With the visual stimuli only, the rat kept the shock at intermediate temporal distances and responded more variably. The behavior with the auditory stimuli alone was quite similar to that produced by the combined stimuli, thus indicating that the auditory stimuli exercised the greater control. When all stimuli were removed, the animal usually kept the shock as far away as the procedure permitted. When only a single pre-shock stimulus was presented, the rat remained quite close to the shock and started to respond predominantly in the pre-shock step.     

Some statistical treatments compatible with individual organism methodology

Consider experimental treatments with consequences so irreversible that baseline performance cannot be recovered. The conventional method of assessing the effects of such treatments by statistical means involves separate experimental and control groups. An alternative proposed here is to administer the experimental treatment to each subject, one subject at a time and in a random order; whenever any subject receives the experimental treatment, those subjects which have not yet received it receive a control treatment. This procedure permits results significant at the one-tailed 0.05 level to be obtained with four subjects; if a two-group procedure evaluated by means of the U test is used, a minimum of six subjects is needed for the same significance level. More generally, the procedure permits equal sensitivity to any experimental effect with over 30% fewer subjects than a two-group procedure. Extensions of the basic method are made to a variety of levels of the experimental treatment and to treatments without irreversible effects, and limitations of the method are discussed.     

A new principle of pellet feeder design

Most current commercial devices dispense dry food pellets by moving the pellets horizontally toward a discharge point. Individual pellets, captured by perforations in a horizontal metal disk, are discharged one by one by stepwise rotation of the disk within the pellet reservoir. In our laboratory, where the average pellet discharge rate is some 20,000 pellets per week, feeders of this type produced occasional problems. Some were electronic; others involved failure always to capture a pellet in each perforation, particularly when the pellet supply was low. But the most common problem was an accumulation of pellet chips and dust under and around the perforated disk, which ultimately jammed the mechanism. Despite weekly cleaning and maintenance, troubles arose at least twice a month, prompting a search for a simpler pellet-feeder design which would be more reliable and require less maintenance. The present pellet feeder employs a vertical rather than horizontal design principle. It has been used extensively in operant conditioning applications for more than a year. More than 200,000 pellets have been reliably discharged from a single feeder without a breakdown. No maintenance, other than a weekly cleaning of the discharge tube, has been required.     

Schedules using noxious stimuli. II: low intensity electric shock as a discriminative stimulus

The presence or absence of pulses of low intensity electric shock was used as a discriminative stimulus to control responding under fixed ratio reinforcement in the squirrel monkey. Initially brief periods of nonreinforcement were lengthened only when discriminative control was evident. Discriminative control was studied by (1) varying the duration of nonreinforcement periods; (2) reversing the stimulus conditions correlated with reinforcement and nonreinforcement periods; and (3) determining the minimum shock intensity necessary to maintain discriminative control. Stimulus control was not reliably affected by d-amphetamine, chlorpromazine, or morphine. The discriminative control by pulses of low intensity electric shock was similar to that by other discriminative stimuli, except that the control developed slowly and was better when the pulsing shock was correlated with reinforcement than when correlated with nonreinforcement.     

Drug effects in squirrel monkeys trained on a multiple schedule with a punishment contingency

The behavior of four monkeys trained on a multiple schedule was differentially sensitive to selected pharmacological agents. The three components of the multiple schedule were: (1) a variable-interval schedule in which responses were reinforced on the average of once per minute; (2) a concurrent schedule in which every tenth response was reinforced and every fifteenth response, on the average, was shocked; and, (3) a neutral stimulus in the presence of which responses were neither reinforced nor shocked. Pentobarbital, chlordiazepoxide, and meprobamate increased responding during each of the components. Scopolamine and d-amphetamine decreased variable-interval performance, had minimal effects on performance during the concurrent-schedule component, and increased responding in the presence of the neutral stimulus. Chlorpromazine decreased variable-interval responding and had slight effects on the responding during the other two components.