The female advantage: sex as a possible protective factor against emotion recognition impairment following traumatic brain injury

Although moderate to severe traumatic brain injury (TBI) leads to facial affect recognition impairments in up to 39% of individuals, protective and risk factors for these deficits are unknown. The aim of the current study was to examine the effect of sex on emotion recognition abilities following TBI. We administered two separate emotion recognition tests (one static and one dynamic) to 53 individuals with moderate to severe TBI (females = 28) and 49 demographically matched comparisons (females = 22). We then investigated the presence of a sex-by-group interaction in emotion recognition accuracy. In the comparison group, there were no sex differences. In the TBI group, however, females significantly outperformed males in the dynamic (but not the static) task. Moreover, males (but not females) with TBI performed significantly worse than comparison participants in the dynamic task. Further analysis revealed that sex differences in emotion recognition abilities within the TBI group could not be explained by lesion location, TBI severity, or other neuropsychological variables. These findings suggest that sex may serve as a protective factor for social impairment following TBI and inform clinicians working with TBI as well as research on the neurophysiological correlates of sex differences in social functioning.     

Associations between Prenatal and Early Childhood Fish and Processed Food Intake,Conduct Problems,and Co-Occurring Difficulties

Little is known about early life diet as a risk factor for early-onset persistent conduct problems (EOP CP). To investigate this, we used data from the Avon Longitudinal Study of Parents and Children, a UK-based prospective epidemiological birth cohort. 5727 mother-child pairs (49.9 % boys) monitored since pregnancy (delivery date between 1 April, 1991 and 31 December, 1992) reported intake of fish and processed foods at 32 weeks gestation and, for the child, at 3 years; EOP (n = 666) and Low conduct problem (Low CP, n = 5061) trajectories were measured from 4 to 13 years; hyperactivity and emotional difficulties were assessed in childhood (4–10 years) and early adolescence (12–13 years), in addition to potential confounding factors (family adversity, birth complications, income). Compared to Low CP, mothers of EOP children consumed less fish (p < 0.01) and more processed food (p < 0.05) prenatally, while EOP children consumed more processed food at 3 years (p < 0.05). For EOP, but not Low CP children, consuming less than two servings/week of fish (vs. two or more servings/week, p < 0.05), and one or more servings/day of processed food (vs. less than one serving/day, p < 0.01), was associated with higher emotional difficulties in early adolescence. Conclusions: Findings suggest that prenatal and postnatal diets high in processed food, and low in fish, associate with an EOP CP trajectory and co-occurring difficulties in early adolescence. As small effect size differences were found, further studies are needed to investigate the long-term impact of early unhealthy diet.     

Responsibility and Reciprocity

Discussions of responsibility typically focus on the person who is held responsible: what are the conditions or criteria of responsibility; what can be done to or demanded of a person who is responsible? This paper shifts focus onto those who hold, rather than those who are held, responsible: what do we owe to those whom we hold responsible? After distinguishing responsibility as answerability from responsibility as liability, it attends mainly to the former, and points out the ways in which it is multiply relational: I am responsible for something to someone who has the standing to call me to account for it, under the norms of some particular practice. Responsibility as thus understood is also reciprocal: if you are to be answerable to me, I must treat you with a certain respect, attend seriously to your answer, and be ready to answer to you myself. The paper explores some of the implications of this point both for our moral dealings with each other, and for criminal law and the criminal trial.     

Collaborative discourse facilitates efficient communication and new learning in amnesia

In previous work we reported robust collaborative learning for referential labels in patients with hippocampal amnesia, resulting in increasingly rapid and economical communication or "common ground" with their partners [Duff, M. C., Hengst, J., Tranel, D., & Cohen, N. J. (2006). Development of shared information in communication despite hippocampal amnesia. Nature Neuroscience, 9(1), 140-146]. The current paper reports the results of discourse analysis, describing the communicative resources and practices used in extended, repeated collaborative interactions, as partners successfully referenced the target cards, managed the task itself, and engaged in non-task talk. Although amnesic pairs showed a normal rate of reduction across trials in the number of words and time-to-completion, their communicative effort was higher overall, particularly the discourse associated with task management, they exhibited a general lack of flexibility in their referential expressions, and they showed a number of striking differences in use of personal and communal knowledge and of multiple perspectives. The interactive sessions provided a potent learning environment, but also a very challenging task in the face of memory impairment. The results give insight into the acquisition of common ground and the manner in which amnesic patients accommodate their memory deficits during real-world interactions, and they have significant implications for memory intervention.     

Characteristics Predicting Effective Outcomes After Coping Effectiveness Training for Patients With Spinal Cord Injuries

Coping effectiveness training (CET), based on R. S. Lazarus and S. Folkmans (1984) theory of stress and coping, teaches appraisal and coping skills. It has been adapted for use with people with spinal cord injuries and the effect of this intervention on coping, anxiety and depression and self perception has been investigated. Using data from P. Kennedy, J. Duff, M. Evans, and A. Beedies (2003) study, the psychological characteristics of people who benefited from CET (no increase in depression and anxiety at the end of CET and 6 weeks after) were compared with those who did not benefit. Coping strategies were not predictive factors but differences in some self-perception items were found between the two groups. Age, gender, level, and type of injury were not shown to be predictive but time since injury was, suggesting that the effectiveness of a CET programme could be maximized by reducing the time between onset of injury and the start of CET.     

Paradoxical drug response and the placebo effect: a discussion of Grunbaum's definitional scheme

Grunbaum claims that the remedial failure of atreatment's characteristic factors is thegeneric, objective property of a placebo. Hestipulates that a treatment is placebic if thisremedial failure exacerbates the targetdisorder. This stipulation can subsume asplacebic effects that might be solelypharmacological, e.g., paradoxical reactions tocertain psychiatric drugs. If that exacerbationcan be explained pharmacologically, then wemight question whether Grunbaum's definitionalscheme captures the core identity of what weusually intend by the placebo concept. Ipropose that this core identity is bestcaptured by a symbolic meaning hypothesis inwhich psychological factors exert thedeterminative influence.     

Storage and processing in visuo-spatial working memory

Visuo-spatial working memory has been used to account for performance in a wide range of visuo-spatial tasks, including perceptuo-motor tracking and immediate recall of visually presented patterns. However a developing body of evidence points to a fractionation of the concept into visuo-spatial processing that calls on general purpose executive resources, and a visual 'cache' memory for temporary storage in on-line cognition. Two related experiments are described which address whether processing and temporary memory draw on overlapping or on distinct resources in working memory. Experiment 1 demonstrates that participants can accurately respond to a series of targets appearing in random locations whether or not they have the additional load of retaining and subsequently recalling the appearance of each target. Memory for target appearance likewise is largely unaffected by the additional load of requiring a response to each target. Experiment 2 demonstrates similar findings when verbal labeling of the patterns is inhibited through the use of articulatory suppression. Results are interpreted as consistent with a multiple component working memory system.