Multiunit changes in hippocampus and medial geniculate body in free-behaving rats during acquisition and retention of a conditioned response to a tone

Multiunit activity (MUA) was recorded chronically in the hippocampus (CA3) and the medial geniculate body (mMG) during habituation to a tone followed by conditioning (tone paired with footshock) or pseudoconditioning (tone/footshock unpaired) in rats previously trained in a lever-pressing for food task (VI 60). In the conditioned group pairing tones with footshocks rapidly induced an increase in the initial CS-evoked response in the mMG, followed by the emergence of a hippocampal response and a marked conditioned suppression of lever-pressing to the tone. In contrast, in the pseudoconditioned group, the stimulus induced only transient cellular changes in the hippocampus and in the mMG, while no behavioral suppression to the tone could be seen. Moreover, presentations of the CS 45 days later induced multiunit and behavioral responses in both structures, only in the conditioned group. These results are used for discussion of the role of learning-induced changes in the sensory structure (mMG) as compared with changes in an associative structure (hippocampus), during acquisition and retention of a conditioned response.     

Learned helplessness in the cockroach (Periplaneta americana)

For 3 consecutive days cockroaches (Periplaneta americana) were exposed to either escapable, inescapable, or no shock in an escape task. Twenty-four hours later they were tested in a shuttlebox escape task. There were reliable differences between escapable and inescapable animals and between inescapable and control animals in both escape latencies and the number of failures to escape.     

Chronic sweet intake lowers pain thresholds without changing brain mu- or delta-opiate receptors

Sprague-Dawley rats drank sweetened (3% dextrose + 0.144% saccharin, w/v) or unflavored water for 18 days and subsequent pain reactivity was assessed using a hot plate. Compared to the rats that consumed unflavored water, the rats that consumed sweet water responded more quickly on the hot plate indicating that their threshold for pain was lowered. Another group of rats given identical exposure to the fluids had their brains prepared for measuring opiate receptor binding using the delta-receptor ligand [3H]D-Ala-D-Leu-enkephalin ([3H]DADLE) and the mu-receptor selective ligand [3H]Tyr-D-Ala-Gly-MePhe-Gly-ol ([ 3H]DAGO). Binding of these opiates to mu- and delta-receptors in the cerebral cortex, striatum, hippocampus, hypothalamus, brain stem, and remaining brain regions was the same for the rats that drank sweet fluids and those that drank unflavored water. These findings suggest that drinking sweet fluids lowers pain thresholds but does not alter mu- and delta-receptors.     

Interactions between area and numerosity

Summary The concept of filled area, i.e. the impressionistic ensemble of parts of a stimulus field occupied by dots, is used to account for various kinds of numerosity illusions due to perceptual interaction between a number of dots and their spatial arrangement. A measure of filled area is derived from a model for the perceptual clustering of dots on the basis of relative proximity. It is shown that the quantified concept of filled area successfully predicts illusion data from earlier studies. Subsequently, a two-alternatives forced-choice numerosity experiment is reported, the data of which gave further evidence of the predictive power of the filled-area hypothesis. Our approach is discussed with respect to spatial features of dot stimuli that might be in rivalry with the filled-area factor in numerosity-estimation tasks.     

Marriage Guidance Training and the Trainee's Own Marriage: A Prospective Study

Twenty trainees and 18 partners took part in a study of the effects of a marriage guidance training programme on their own marriage. Changes were assessed in two ways: retrospectively ('perceived' changes as assessed following training) and prospectively (changes calculated by comparing scores obtained before training and those obtained after training). For most dimensions there was little correspondence between 'perceived' change and 'calculated' change. This has important methodological implications, which are discussed. The 'calculated' change indicated poorer marital adjustment following training. The trainees' scores suggested that they had become less 'abasing' and less 'nurturant' towards their partners; also that they had more disagreements about 'philosophy of life' and 'dealing with in-laws'. Their comments suggested that a number of the trainees had become more analytical of their own marriages, and that training had heightened their awareness of their own needs and individuality.     

Insight-oriented group psychotherapy of latency-age children in an acute care setting

Traditional approaches to group therapy with latency-age children have stressed activity and nonverbal therapeutic interventions. These approaches originated in the 1940s with Slavson's activity aroup therapy. A review of the literature of the past 25 years reveals that many clinicians have increasingly employed verbal techniques with latencyage groups. Most such reports describe groups for latency-age out-patients. In this paper, a verbal, interpretive technique for group therapy with latency-age inpatients is described. Clinical vignettes are included to illustrate this technique. Our experience suggests that such a technique can become an integral part of the inpatient treatment program for the latency-age child.     

Individual differences in reverse Hindsight bias: I never thought something like chernobyl would happen. Did I?

Hindsight bias was studied in the context of the accident in the Chernobyl nuclear power plant, which took place on April 26th 1986. An individual difference factor which relates to the motivation to process information, need for cognition, was expected to moderate the occurrence of hindsight bias. Probability estimates of many casualties due to the use of nuclear power in The Netherlands were obtained from 212 individuals two months before the accident in Chernobyl. These estimates were compared with similar estimates made in hindsight by the same individuals five months after the accident. Loglinear Analyses reveal a systematic hindsight bias. However, the direction of the bias was contrary to expectations. In hindsight, individuals gave lower probabilities than they actually did two months before the Chernobyl accident. These results reveal a reverse hindsight bias. As hypothesized, need for cognition moderates hindsight bias: individuals low and medium in need for cognition express a systematic reverse hindsight bias, while individuals high in need for cognition do not. High need for cognition individuals also show higher literal consistency between the two measurements, which supports a memory explanation of the moderating effect of need for cognition.     

Professional liability (malpractice) coverage of humanist scholars functioning as clinical medical ethicists

In contrast to theoretical discussions about potential professional liability of clinical ethicists, this report gives the results of empirical data gathered in a national survey of clinical medical ethicists. The report assesses the types of activities of clinical ethicists, the extent and types of their professional liability coverage, and the influence that concerns about legal liability has on how they function as clinical ethicists. In addition demographic data on age, sex, educational background, etc. are reported. The results show that while nearly one third (28.9%) of the ethicists regularly make recommendations about patient care, only 10.8% of them regularly make entries in the medical record; only approximately half (53.0%) of them are covered by professional liability (malpractice) insurance; and the vast majority (84.3%) of them say that concerns about legal liability do not influence the way they function as clinical ethicists.