The Tourette's Disorder Scale (TODS): development, reliability, and validity

To address the lack of a simple and standardized instrument to assess overall illness severity of Tourette's disorder (TD), the authors developed and tested a 15-item scale to measure a broad range of common symptoms including tics, inattention, hyperactivity, obsessions, compulsions, aggression, and emotional symptoms. Independent investigators used the 15-item Tourette's Disorder Scale (TODS) to assess 60 TD patients who were taking part in a double-blind placebo-controlled multicenter 8-week treatment study. Interrater reliability, internal consistency, convergent and discriminant validity, and sensitivity to change were examined. The TODS was associated with good interrater reliability, excellent internal consistency, and favorable levels of validity and sensitivity to change. Individual TODS items showed good convergent and discriminant validity against other measures. The TODS is a simple, efficient way for clinicians and parents to rate the severity of multiple symptoms commonly found in patients with Tourette's disorder.     

Involuntary sterilization of persons with mental retardation: an ethical analysis

Legitimate concerns on the part of parents and guardians may lead to requests for sterilization of a mentally retarded person in their care. At the same time, mentally retarded persons must be protected from actions that do not serve their best interests. This paper will review the history of involuntary sterilization in the United States and evaluate the ethical arguments that are relevant to decisions about involuntary sterilization. While other, less permanent forms of contraception might be acceptable, involuntary sterilization ought not be performed on mentally retarded persons who retain the capacity for reproductive decision-making, the ability to raise a child, or the capacity to provide valid consent to marriage. Mentally retarded persons who lack capacity in those three areas should be considered for involuntary sterilization only when the procedure is necessary, sterilization would serve the best interests of the mentally retarded person, less intrusive and temporary methods of contraception or control of menstruation are not acceptable alternatives, and procedural safeguards have been implemented to assure a fair decision-making process.     

Exploring the role of individual differences in the prediction of workplace aggression

This study investigates the relationship between individual differences and the incidence of workplace aggression in a sample of employees from a transportation company and a public school system. Hierarchical multiple regression analysis indicated that measures of trait anger, attribution style, negative affectivity, attitudes toward revenge, self-control, and previous exposure to aggressive cultures accounted for 62% of the variance in the participants' self-reported incidence of workplace aggression. Further research on workplace aggression is advocated, focusing on the role of individual differences and their interactions with organizational and group-level variables.     

Evaluation of agricultural research in Latin America and the Caribbean

This article assesses the state of evaluation, and identifies priorities for improving evaluation, in agricultural research organizations in the region of Latin America and the Caribbean in the early 1990s. Based on thirteen case studies conducted in 1992, the article describes the institutional settings and regional patterns, and trends in evaluation practice. Illustrative cases from Argentina, Brazil, and Guatemala are presented. The organizations studied have extensive experience with evaluation; however, this experience has not been well documented or shared. Evaluation is generally the weakest phase in the management cycle. In the past, most evaluations have been extrinsically motivated, and as such, they have been of little use to local researchers and managers. Obstacles to improving evaluation include the centralization of administrative systems, weak program management, a lack of understanding of potential uses of evaluation in management, and limited knowledge of appropriate evaluation methods. Agricultural research managers feel that evaluation training should be provided as one component of a broader effort covering planning, monitoring, and evaluation. Since joining ISNAR in 1990, he has engaged in research, training, and advisory work on research management, with an emphasis on evaluation. Previously, for fifteen years Horton was head of the social science department of the International Potato Center in Peru. Horton received B.s. and M.S. degrees in agricultural economics from the University of Illinois and a Ph.D. in economics from Cornell University. His current interests include action research and learning, organizational assessment, and institutionalization of planning, monitoring, and evaluation. He worked for fourteen years at the Brazilian Corporation for Agricultural Research, conducting research and development activities in the areas of human resources and of strategic management. He is a full professor at the Department of Social and Work Psychology, Institute of Psychology, University of Brasilia, Brazil, where he teaches and advises at the undergraduate and graduate levels and does research and consulting. His current areas of interest are organizational behavior, training, organizational evaluation, and science and technology management.     

Hippocampal EEG and Unit Activity Responses to Modulation of Serotonergic Median Raphe Neurons in the Freely Behaving Rat

Hippocampal EEG, GABAergic interneurons, and principal cells were recorded simultaneously as rats foraged within one of three environments both before and after modulation of serotonergic inputs to the hippocampus. Median raphe microinjections of the 5-HT1a receptor agonist 8-OH-DPAT were made to produce inhibition of serotonergic neurons in this region. Such microinjections produced behavioral arousal and increases in the amplitude of hippocampal EEG theta. Consistent with the pattern of serotonergic innervation of the hippocampus, the GABAergic interneuron population was affected differentially by the microinjections. Principal cells were generally unaffected by the manipulation and maintained robust spatial firing correlates within the foraging environment. The results provide basic data on the relationship between serotonergic median raphe neurons and hippocampal activity in a behaving animal. The data suggest that behavioral responses to manipulation of the serotonergic system are mediated by brain regions other than the hippocampus or are mediated through changes in the activity of hippocampal interneurons.     

The semantic side of decision making

The research reported in this paper follows the perspective that decision making is a meaningful act that conveys information. Furthermore, the potential meanings associated with decision options may affect the decisions themselves. This idea is examined in the contexts of compensation, donation, and exchange. In general, judgments were relation dependent and meaning dependent. Furthermore, the results show nonmonotonicities and limited substitutability in a pattern that challenges straightforward ways of mapping decisions onto a common currency of utility.     

Natural Theology in Paul? Reading Romans 1.19–20

This reading of Romans 1.19–20 suggests that, viewed within the argumentative progression of the letter from 1.18–3.20, these verses are properly understood as a subversion of the premises of natural revelation, rather than an endorsement of them. The traditional account of Paul's argument, in which 1.19–20 announces a theology of natural knowledge of God, is contradicted both by Paul's wider theological commitments and by his attitude to the privileges of Judaism. An alternative construal of the argument considers it as an ad hominem strategy, in which the opening verses serve to recapitulate at the beginning of the argument the presuppositions that Paul seeks ultimately to overthrow.