Effects of daily environmental enrichment on memory deficits and brain injury following neonatal hypoxia-ischemia in the rat

Environmental enrichment (EE) results in improved learning and spatial memory, as well as attenuates morphological changes resulting from cerebral ischemia in adult animals. This study examined the effects of daily EE on memory deficits in the water maze and cerebral damage, assessed in the hippocampus and cerebral cortex, caused by neonatal hypoxia-ischemia. Male Wistar rats in the 7th postnatal day were submitted to the Levine-Rice model of neonatal hypoxia-ischemia (HI), comprising permanent occlusion of the right common carotid artery and a period of hypoxia (90 min, 8%O(2)-92%N(2)). Starting two weeks after the HI event, animals were stimulated by the enriched environment (1h/day for 9 weeks); subsequent to the stimulation, performance of animals in the water maze was assessed. HI resulted in spatial reference and working memory impairments that were completely reversed by EE. Following the behavioral study, animals were killed and the hippocampal volume and cortical area were estimated. There was a significant reduction of both hippocampal volume and cortical area, ipsilateral to arterial occlusion, in HI animals; environmental stimulation had no effect on these morphological measurements. Presented data indicate that stimulation by the daily environmental enrichment recovers spatial memory deficits caused by neonatal hypoxia-ischemia without affecting tissue atrophy in either hippocampus or cortex.     

On the origins of background emotions: from affect synchrony to symbolic expression

Guided by Damasio's (2003) formulations on background emotions, this study examined the contour of infant affect during interactions with mother and father in relation to the emergence of symbolic expression. One hundred parents and infants were observed in face-to-face interactions and in play sessions at the toddler stage. Parent's and infants' affective states were coded in 1-s frames, and synchrony was assessed. Toddlers' play was microcoded for symbolic level and for reciprocity and intrusiveness. Infant affective contour with mother was rhythmic with 1 episode of positive arousal framed by social gaze. Affective contour with father contained several peaks of positive arousal of shorter duration. Symbolic complexity was comparable and preserved the parent-specific contours, with quicker latencies, higher frequencies, and shorter durations of complex symbolic episodes with father. Sequential relations emerged between parent's and child's symbolic expression, and maternal reciprocity and intrusiveness were sequentially linked to symbolic expansion or constriction, respectively. Parent-infant synchrony and the parent's support of toddler symbolic play predicted symbolic complexity. The need to include time in research on emotions and the dyadic origins of positive emotions are discussed.     

The impact of cultural context on Brazilian adolescents' sexual practices

AIDS prevention research has demonstrated that theoretically driven HIV prevention programs can be tailored to specific cultures. Further, condom self-efficacy and contraceptive self-efficacy scales have been tested in the U.S. and been shown to predict condom and contraceptive use. Results of condom and contraceptive self-efficacy studies have been used to suggest ways to educate and counsel young people to avoid unprotected sex. This paper reports the findings from our research in Salvador, Brazil, using Levinson's Condom Self-Efficacy Scale (CDSE). The data are derived from six focus groups totaling 76 teenagers from three high schools. The focus group discussions explored cultural and psychological issues involved in condom use. Here we report on the gender dynamics of condom use as revealed by these urban Brazilian teenagers. Three focal points for behavioral change are identified: (1) issues of masculinity, (2) issues of femininity, and (3) condom use skills.     

Caregiving representations of mothers of behaviorally inhibited and uninhibited preschool children

This study examined differences in the caregiving representations of mothers of 3- to 4-year-old behaviorally inhibited and uninhibited children with secure or insecure attachments. Mothers of inhibited children perceived their children as more vulnerable than did mothers of uninhibited children, and they acknowledged difficulties associated with their children's inhibited temperament. However, mothers of insecure inhibited children were less likely than mothers of secure inhibited children to validate their children's emotional experiences and to be aware of their children's internal states and perspectives, and they showed higher levels of boundary violation and defense against negative affect. Implications of the more problematic caregiving representations of mothers of insecure inhibited children for parent-child relationships are discussed.     

Encoding under trust and distrust: the spontaneous activation of incongruent cognitions

Past studies of strategic thinking have shown that the encoding of the message information becomes more complex under distrust. Receivers process the information as if they are trying to protect themselves from being misled by testing alternative potential interpretations. The present study investigates the possibility that when people are mistrustful they spontaneously activate associations that are incongruent with the given message. Findings from 3 experiments suggest that, even when the distrust is unrelated in any meaningful way to the message and even when receivers are unable to prepare a strategic response, the cognitive system reacts to distrust by automatically inducing the consideration of incongruent associations--it seems designed to ask, "and what if the information were false?" The theoretical implications of the results for theories of social perception and persuasion are discussed.     

Processing doubly quantified sentences: Evidence from eye movements

We investigated the processing of doubly quantified sentences, such asKelly showed a photo to every critic, that are ambiguous as to whether the indefinite (a photo) specifies single or multiple referents. Ambiguity resolution requires the computation of relative quantifier scope: Whether a or every takes wide scope, thereby determining how many entities or events are to be represented. In an eye-tracking experiment, we manipulated quantifier order and whether continuations were singular or plural, for constructions with the direct or the indirect object occurring first. We obtained effects consistent with the on-line processing of relative scope at the doubly quantified phrase and considered two possible explanations for a preference for singular continuations to the quantified sentence. We conclude that relative quantifier scope is computed on line during reading but may not be a prerequisite for the resolution of definite anaphors, unless required by secondary tasks.     

Assessment of mindfulness by self-report: the Kentucky inventory of mindfulness skills

A self-report inventory for the assessment of mindfulness skills was developed, and its psychometric characteristics and relationships with other constructs were examined. Participants included three samples of undergraduate students and a sample of outpatients with borderline personality disorder Based on discussions of mindfulness in the current literature, four mindfulness skills were specified: observing, describing, acting with awareness, and accepting without judgment. Scales designed to measure each skill were developed and evaluated. Results showed good internal consistency and test-retest reliability and a clear factor structure. Most expected relationships with other constructs were significant. Findings suggest that mindfulness skills are differentially related to aspects of personality and mental health, including neuroticism, psychological symptoms, emotional intelligence, alexithymia, experiential avoidance, dissociation, and absorption.     

The limitations of "vulnerability" as a protection for human research participants

Vulnerability is one of the least examined concepts in research ethics. Vulnerability was linked in the Belmont Report to questions of justice in the selection of subjects. Regulations and policy documents regarding the ethical conduct of research have focused on vulnerability in terms of limitations of the capacity to provide informed consent. Other interpretations of vulnerability have emphasized unequal power relationships between politically and economically disadvantaged groups and investigators or sponsors. So many groups are now considered to be vulnerable in the context of research, particularly international research, that the concept has lost force. In addition, classifying groups as vulnerable not only stereotypes them, but also may not reliably protect many individuals from harm. Certain individuals require ongoing protections of the kind already established in law and regulation, but attention must also be focused on characteristics of the research protocol and environment that present ethical challenges.