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11.
Early lexical development in children with focal brain injury 总被引:4,自引:0,他引:4
Donna J. Thal Virginia Marchman Joan Stiles Dorothy Aram Doris Trauner Ruth Nass Elizabeth Bates 《Brain and language》1991,40(4):491-527
Early lexical development in 27 children with focal brain injury was studied cross-sectionally and longitudinally. Data were obtained from children between 12 and 35 months of age who acquired their lesion prenatally or within the first 6 months of life. Results for the group as a whole provide clear evidence for delays in lexical comprehension and production, and for a larger number of comprehension/production dissociations than would be expected by chance. In addition, a significant number of children were observed having unusual difficulty mastering predication and/or using an atypically high proportion of closed class words (suggesting reliance on holistic/formulaic speech). Analyses by lesion type revealed no effect of lesion size. Analyses according to side of lesion revealed that children with right-hemisphere damage produced a higher proportion of closed class words, suggesting heavy reliance on well-practiced but under-analyzed speech formulae. Children with left-hemisphere damage were slightly better in comprehension than children with right-hemisphere damage. In addition, left posterior lesions were associated with greater delays in expressive language, and delays were more protracted in children with left posterior damage. No differential effects of left posterior damage were found for lexical comprehension. 相似文献
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Doris Aaronson 《Behavior research methods》1979,11(2):159-162
In recent years, users of Digital Equipment Corporation (DEC) computers have been offered compatible products manufactured by other companies. This paper reviews the results of a survey concerning the purchase and use of non-DEC products; comments concerning advantages or disadvantages of buying DEC vs. non-DEC products are noted. 相似文献
14.
Jennifer Barber Watson Hugo H. Gregory Doris J. Kistler 《Journal of Fluency Disorders》1987,12(6):429-450
The purpose of this study was to develop and evaluate a procedure to assess adult stutterers' communication attitudes. To this end, the investigation was divided into two phases. In Phase I, an assessment inventory based on a tripartite attitudinal model was developed and administered to 107 adult stutterers. Reliability and validity of these procedures were examined, and the inventory was refined. In Phase II, reliability and validity of the attitude assessment procedures were reassessed, and the attitudes of 26 stutterers and 56 nonstutterers were examined. Assessment procedures involved a self-report inventory, which obtained ratings of items in 13 situational subscales representing different speaking situations. These situations were rated using four response scales reflecting behavioral, affective, and cognitive aspects of attitude. Situational responding, response scale scores, and response scale interrelationships are examined. Findings are discussed in terms of the potential value of the inventory and future investigations. 相似文献
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Two forms of thinking about the future are distinguished: expectations versus fantasies. Positive expectations (judging a desired future as likely) predicted high effort and successful performance, but the reverse was true for positive fantasies (experiencing one's thoughts and mental images about a desired future positively). Participants were graduates looking for a job (Study 1), students with a crush on a peer of the opposite sex (Study 2), undergraduates anticipating an exam (Study 3), and patients undergoing hip-replacement surgery (Study 4). Effort and performance were measured weeks or months (up to 2 years) after expectations and fantasies had been assessed. Implications for the self-regulation of effort and performance are discussed. 相似文献
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The aim of this study was to investigate unconscious priming by the use of a spatial mirror-masking paradigm. Words and nonwords with no under-length letters are mirrored at their horizontal axis. The results are figures of geometric-like forms that contain letters in their upper part. In the three experiments reported in this study, a priming procedure used such mirrored words and nonwords as primes. Participants were ignorant of the nature of the construction of the stimuli. Perceptual reports of the participants revealed that they did not realize that words were hidden in the primes. Nevertheless, they showed priming in all three experiments. Priming effects were replicated with prime-target SOAs of between 1 and 3 s. Functional dissociations were found between ignorant and informed participants. Informed groups showed perceptual and semantic priming, while ignorant groups showed only perceptual priming. 相似文献
19.
Kindling-induced changes in plasticity of the rat amygdala and hippocampus 总被引:3,自引:0,他引:3 下载免费PDF全文
Schubert M Siegmund H Pape HC Albrecht D 《Learning & memory (Cold Spring Harbor, N.Y.)》2005,12(5):520-526
Temporal lobe epilepsy (TLE) is often accompanied by interictal behavioral abnormalities, such as fear and memory impairment. To identify possible underlying substrates, we analyzed long-term synaptic plasticity in two relevant brain regions, the lateral amygdala (LA) and the CA1 region of the hippocampus, in the kindling model of epilepsy. Wistar rats were kindled through daily administration of brief electrical stimulations to the left basolateral nucleus of the amygdala. Field potential recordings were performed in slices obtained from kindled rats 48 h after the last induced seizure, and in slices from sham-implanted and nonimplanted controls. Kindling resulted in a significant impairment of long-term potentiation (LTP) in both the LA and the CA1, the magnitude of which was dependent on the number of prior stage V seizures. Saturation of CA1-LTP, assessed through repeated spaced delivery of high-frequency stimulation, occurred at lower levels in kindled compared to sham-implanted animals, consistent with the hypothesis of reduced capacity of further synaptic strengthening. Furthermore, theta pulse stimulation elicited long-term depression in the amygdala in nonimplanted and sham-implanted controls, whereas the same stimulation protocol stimulation caused LTP in kindled rats. In conclusion, kindling differentially affects the magnitude, saturation, and polarity of LTP in the CA1 and LA, respectively, most likely indicating an activity-dependent mechanism in the context of synaptic metaplasticity. 相似文献
20.
Thomasma D 《Theoretical medicine and bioethics》2005,26(6):441-443
Theoretical Medicine and Bioethics - 相似文献