On the predictive validity of various corpus-based frequency norms in L2 English lexical processing

The predictive validity of various corpus-based frequency norms in first-language lexical processing has been intensively investigated in previous research, but less attention has been paid to this issue in second-language (L2) processing. To bridge the gap, in the present study we took English as a case in point and compared the predictive power of a large set of corpus-based frequency norms for the performance of an L2 English visual lexical decision task (LDT). Our results showed that, in general, the frequency norms from SUBTLEX-US and WorldLex–Blog tended to predict L2 performance better in reaction times, whereas the frequency norms from corpora with a mixture of written and spoken genres (CELEX, WorldLex–Blog, BNC, ANC, and COCA) tended to predict L2 accuracy better. Although replicated in both low- and high-proficiency L2 English learners, these patterns were not exactly the same as those found in LDT data from native English speakers. In addition, we only observed some limited advantages of the lemma frequency and contextual diversity measures over the wordform frequency measure in predicting L2 lexical processing. The results of the present study, especially the detailed comparisons among the different corpora, provide methodological implications for future L2 lexical research.     

Genetic Testing and Parkinson Disease: Assessment of Patient Knowledge,Attitudes, and Interest

The most common genetic contributor to late-onset Parkinson disease (PD) is the LRRK2 gene. In order to effectively integrate LRRK2 genetic testing into clinical practice, a strategy tailored to the PD population must be developed. We assessed 168 individuals with PD for baseline knowledge of genetics, perceived risk, and interest and opinions regarding genetic counseling and testing. Most participants felt that they were familiar with general genetics terms but overall knowledge levels were low, with an average score of 55%. The majority of participants thought it was likely they inherited a PD gene (72%), believed genetic testing for PD would be useful (86%), and were interested in genetic testing (59%) and genetic counseling (56%). However, only a few participants had heard of any genetic tests for PD (29%) or LRRK2 (10%). There appears to be a significant level of interest in genetics and genetic testing within the PD population, but a considerable deficit in genetics knowledge and an over-estimation of risk. Genetic education and counseling tools to address these needs were developed to provide patients with the ability to make informed and knowledgeable genetic testing decisions.     

略论“延续性医德教育”模式的内涵与构建

目前医德教育在教育时间与教育手段等方面缺乏延续性。通过对医德教育的特点和规律以及传统医德教育存在的弊病、医疗领域不正之风的负面影响等问题的分析,提出应着手构建在校医学生—实习生—在职医务人员"三位一体"的"延续性医德教育"模式,实现"第一课堂与第二课堂"、"系统医德理论与实践"、"被动性与自主性"医德教育三结合。     

Perceptions of fear in other Children and adolescents: The role of gender and friendship status

Gender differences in fear were examined in 693 Chinese children and adolescents. Subjects were asked to rate their own fears, the fears of their best friends, and the fears of other classmates using the Fear Survey Schedule for Children — Revised (Ollendick, 1983). Consistent with previous investigations in Western and Eastern countries, girls rated themselves as more fearful than boys. In addition, both girls and boys rated their best friends as similar in number, content, and intensity of fears. However, girls rated their classmates as less fearful than themselves or their best friends, while boys rated their classmates as more fearful than themselves or their best friends. Findings are discussed in terms of gender role expectations and similarity-attraction hypotheses.     

The auditory motion aftereffect: its tuning and specificity in the spatial and frequency domains

In this paper, the auditory motion aftereffect (aMAE) was studied, using real moving sound as both the adapting and the test stimulus. The sound was generated by a loudspeaker mounted on a robot arm that was able to move quietly in three-dimensional space. A total of 7 subjects with normal hearing were tested in three experiments. The results from Experiment 1 showed a robust and reliable negative aMAE in all the subjects. After listening to a sound source moving repeatedly to the right, a stationary sound source was perceived to move to the left. The magnitude of the aMAE tended to increase with adapting velocity up to the highest velocity tested (20 degrees/sec). The aftereffect was largest when the adapting and the test stimuli had similar spatial location and frequency content. Offsetting the locations of the adapting and the test stimuli by 20 degrees reduced the size of the effect by about 50%. A similar decline occurred when the frequency of the adapting and the test stimuli differed by one octave. Our results suggest that the human auditory system possesses specialized mechanisms for detecting auditory motion in the spatial domain.     

A cGMP-dependent protein kinase gene, foraging, modifies habituation-like response decrement of the giant fiber escape circuit in Drosophila

The Drosophila giant fiber jump-and-flight escape response is a model for genetic analysis of both the physiology and the plasticity of a sensorimotor behavioral pathway. We previously established the electrically induced giant fiber response in intact tethered flies as a model for habituation, a form of nonassociative learning. Here, we show that the rate of stimulus-dependent response decrement of this neural pathway in a habituation protocol is correlated with PKG (cGMP-Dependent Protein Kinase) activity and foraging behavior. We assayed response decrement for natural and mutant rover and sitter alleles of the foraging (for) gene that encodes a Drosophila PKG. Rover larvae and adults, which have higher PKG activities, travel significantly farther while foraging than sitters with lower PKG activities. Response decrement was most rapid in genotypes previously shown to have low PKG activities and sitter-like foraging behavior. We also found differences in spontaneous recovery (the reversal of response decrement during a rest from stimulation) and a dishabituation-like phenomenon (the reversal of response decrement evoked by a novel stimulus). This electrophysiological study in an intact animal preparation provides one of the first direct demonstrations that PKG can affect plasticity in a simple learning paradigm. It increases our understanding of the complex interplay of factors that can modulate the sensitivity of the giant fiber escape response, and it defines a new adult-stage phenotype of the foraging locus. Finally, these results show that behaviorally relevant neural plasticity in an identified circuit can be influenced by a single-locus genetic polymorphism existing in a natural population of Drosophila.     

The auditory motionaftereffect: Its tuning and specificity in the spatial and frequency domains

In this paper, the auditory motion aftereffect (aMAE) was studied, using real moving sound as both the adapting and the test stimulus. The sound was generated by a loudspeaker mounted on a robot arm that was able to move quietly in three-dimensional space. A total of 7 subjects with normal hearing were tested in three experiments. The results from Experiment 1 showed a robust and reliable negative aMAE in all the subjects. After listening to a sound source moving repeatedly to the right, a stationary sound source was perceived to move to the left. The magnitude of the aMAE tended to increase with adapting velocity up to the highest velocity tested (20°/sec). The aftereffect was largest when the adapting and the test stimuli had similar spatial location and frequency content. Offsetting the locations of the adapting and the test stimuli by 20° reduced the size of the effect by about 50%. A similar decline occurred when the frequency of the adapting and the test stimuli differed by one octave. Our results suggest that the human auditory system possesses specialized mechanisms for detecting auditory motion in the spatial domain.     

大学生心理压力感基本特点的调查研究

本研究采用自编的大学生心理压力感问卷对全国 1 3所大学共 2 0 0 7名大学生的心理压力感状况进行了调查研究。结果表明 :(1 )在大学生群体中心理压力感的主要来源依次有学业压力、学校环境压力、情绪压力、择业压力和人际压力 ,大都是社会环境方面的原因 ;(2 )从大学生心理压力感的年级发展趋势看 ,二、三年级的大学生在各方面的压力感均高于一、四年级 ;(3 )女生在择业和学业压力感方面高于男生 ,男生在家庭、恋爱、身体健康、适应和挫折方面的压力感高于女生 ;(4)来自乡村的大学生在家庭、择业和学校环境方面的压力感高于来自城市的大学生 ;(5)在家庭、择业、学校环境和学业压力感方面非独生子女高于独生子女     

情绪加工的脑机制研究及其现状

本文从情绪的效价载荷及其脑功能成像研究、面部表情的识别及其脑功能成像研究以及情绪的诱发及其脑功能成像研究等三方面介绍了情绪加工的脑机制及其研究现状。从现有的研究成果来看,大脑皮层在加工不同效价载荷的情绪时具有很大的重叠性;有关面部表情识别的研究表明,不同的神经环路负责调节对不同面部表情的反应;有关诱发的情绪的研究表明,前扣带回皮层在表征实验诱发的情绪时扮演着一个非常重要的角色。文章最后指出了情绪研究目前面临的一些问题,并指出在我国开展情绪的脑机制研究的重要意义。