Does emotion help or hinder immediate memory? Arousal versus priority-binding mechanisms

People recall taboo words better than neutral words in many experimental contexts. The present rapid serial visual presentation (RSVP) experiments demonstrated this taboo-superiority effect for immediate recall of mixed lists containing taboo and neutral words matched for familiarity, length, and category coherence. Under binding theory (MacKay et al., 2004), taboo superiority reflects an interference effect: Because the emotional reaction system prioritizes binding mechanisms for linking the source of an emotion to its context, taboo words capture the mechanisms for encoding list context in mixed lists, impairing the encoding of adjacent neutral words when RSVP rates are sufficiently rapid. However, for pure or unmixed lists, binding theory predicted no better recall of taboo-only than of neutral-only lists at fast or slow rates. Present results supported this prediction, suggesting that taboo superiority in immediate recall reflects context-specific binding processes, rather than context-free arousal effects, or emotion-linked differences in rehearsal, processing time, output interference, time-based decay, or guessing biases.     

Changing perspectives on the benefits of newborn screening

The likelihood of benefit is fundamental to decision making about newborn screening. But benefit is construed in different ways by different stakeholders. This article begins with a review of benefit as considered historically by various expert panels and organizations. We then show how 78 conditions fared when experts recently rated them on benefit using a scoring system recommended by a task force of the American College of Medical Genetics. Finally, we analyze how benefit is reflected in the public comments submitted in response to the ACMG report. Results show that benefit has been and remains a core consideration for screening decisions. Historically the focus has been on improved physical health as a result of medical treatment; however, in only 4 of the 78 conditions rated does newborn screening prevent all negative consequences. In fact the majority of both core conditions (51.7%) and secondary targets (87.5%) recommended in the ACMG report were rated as having treatments that prevented only some negative consequences. All conditions rated had perceived benefits for family and society, but currently no conditions are screened on the basis of family or societal benefits alone. No agreed-upon threshold exists for what would be considered meaningful benefit, and stakeholder groups differ in their perceptions of benefit. We conclude by suggesting several key research studies needed to further inform public policy.     

Making sense of sentences in schizophrenia: electrophysiological evidence for abnormal interactions between semantic and syntactic processing

Event-related potentials to critical verbs were measured as patients with schizophrenia and healthy controls read sentences word by word. Relative to their preceding context, critical verbs were (a) congruous, (b) incongruous and semantically unrelated to individual preceding words (pragmatic-semantic violations), (c) incongruous but semantically related to individual preceding words (animacy-semantic violations), or (d) syntactically anomalous. The N400 was modulated normally in patients, suggesting that semantic integration between individual words within sentences was normal in schizophrenia. The amplitude of the P600 to both syntactic and animacy-semantic violations was reduced in patients relative to controls. The authors suggest that, in schizophrenia, an abnormality in combining semantic and syntactic information online to build up propositional meaning leaves sentence processing to be primarily driven by semantic relationships between individual words.     

Paul E. Meehl's contributions to personality assessment

Many of Meehl's interests converged in his work on personality assessment. In empirical research, development of the K scale of the Minnesota Multiphasic Personality Inventory and various scales of other tests are noteworthy, but his most profound contributions were conceptual and philosophical. Essays on the role of base rates in clinical decision and on construct validity in psychological tests provided vital insights on core issues in assessment. The concept of nomological nets allowed systematic investigation of unobservable theoretical entities, with liberating effects on all natural sciences. An active clinician, Meehl understood deeply the complexities of professional service, but his insistence on empirical validation as the ultimate arbiter of the value of any procedure required all attainable rigor in the scientific foundations of clinical practice.     

Measurement of speech disfluency through magnitude estimation and interval scaling

The purpose was to assess whether equal-appearing interval or magnitude-estimation scaling resulted in a data set with a closer correlation to the physical stimuli, made up of speech samples with varying amounts of disfluency. 20 young adults completed two tasks. In Task 1, subjects used a 7-point equal-appearing interval scale to rate the disfluency of 10 speech samples having varying within sentence pause, presented randomly at 65 dB SPL. In Task 2, subjects used magnitude-estimation scaling to rate these stimuli, presented in a randomized order. Analysis showed significantly high correlations for both scaling techniques and the speech stimuli (Spearman rho=.90 and 1.00, respectively). It appears that subjects can use either scaling technique to rate accurately varied speech disfluency.     

Reduced electrodermal activity in psychopathy-prone adolescents

This study tests the hypothesis that psychopathy-prone adolescents show reduced anticipatory skin conductance responding. Electrodermal activity was recorded while participants anticipated and responded to a 105 dB signaled or unsignaled white-noise burst. Using an extreme groups design, the authors used Child Psychopathy Scale (D. R. Lynam, 1997) scores from a community sample of 335 male adolescents (age 16) to form control (n = 65) and psychopathy-prone (n = 65) groups. Significantly more psychopathy-prone participants were nonresponders in the signaled anticipatory (p = .014), signaled responsivity (p = .037), and unsignaled responsivity (p = .003) conditions compared with controls. Anticipatory hyporesponsivity of psychopathy-prone adolescents similar to the electrodermal hyporesponsivity found in psychopathic adults suggests that this autonomic impairment is present by adolescence and may predispose individuals to adult psychopathy.     

Evaluation of Five Procedures for Classification of Participants’ Fear Levels

The present study evaluated the ability of 5 different fear classification procedures to discriminate between 3 fear levels and to correlate with 6 commonly used dependent measures of fear. A standardized fear assessment procedure was administered on 2 separate trials to 71 women participants. Following the completion of the assessment trials, the participants data were scored and regrouped according to 5 fear classification procedures (behavioral, self-report, skin conductance level, skin response amplitude, and heart rate). This design permitted each procedure to be evaluated to the same target stimulus and at the same point in time. The classifications of participants on the basis of behavior and skin conductance response were found to be most effective selection procedures with self-report, skin conductance level, and heart rate being the least. Reliability of the findings was assessed by a test–retest procedure.     

Hippocampal inactivation enhances taste learning

Learning tasks are typically thought to be either hippocampal-dependent (impaired by hippocampal lesions) or hippocampal-independent (indifferent to hippocampal lesions). Here, we show that conditioned taste aversion (CTA) learning fits into neither of these categories. Rats were trained to avoid two taste stimuli, one novel and one familiar. Muscimol infused through surgically implanted intracranial cannulae temporarily inactivated the dorsal hippocampus during familiarization, subsequent CTA training, or both. As shown previously, hippocampal inactivation during familiarization enhanced the effect of that familiarization on learning (i.e., hippocampal inactivation enhanced latent inhibition of CTA); more novel and surprising, however, was the finding that hippocampal inactivation during training sessions strongly enhanced CTA learning itself. These phenomena were not caused by specific aspects of our infusion technique--muscimol infusions into the hippocampus during familiarization sessions did not cause CTAs, muscimol infusions into gustatory cortex caused the expected attenuation of CTA, and hippocampal inactivation caused the expected attenuation of spatial learning. Thus, we suggest that hippocampal memory processes interfere with the specific learning mechanisms underlying CTA, and more generally that multiple memory systems do not operate independently.