Frontolimbic response to negative feedback in clinical depression

Functional neuroimaging suggests that limbic regions of the medial frontal cortex may be abnormally active in individuals with depression. These regions, including the anterior cingulate cortex, are engaged in both action regulation, such as monitoring errors and conflict, and affect regulation, such as responding to pain. The authors examined whether clinically depressed subjects would show abnormal sensitivity of frontolimbic networks as they evaluated negative feedback. Depressed subjects and matched control subjects performed a video game in the laboratory as a 256-channel EEG was recorded. Speed of performance on each trial was graded with a feedback signal of A, C, or F. By 350 ms after the feedback signal, depressed subjects showed a larger medial frontal negativity for all feedback compared with control subjects with a particularly striking response to the F grade. This response was strongest for moderately depressed subjects and was attenuated for subjects who were more severely depressed. Localization analyses suggested that negative feedback engaged sources in the anterior cingulate and insular cortices. These results suggest that moderate depression may sensitize limbic networks to respond strongly to aversive events.     

Accuracy and Confidence in Person Identification: The Relationship Is Strong When Witnessing Conditions Vary Widely

We hypothesized that both accuracy and confidence in suspect identifications depend, in part, on participants' ability to identify the target, and that both accuracy and confidence therefore tend to be higher under conditions that lead to good memory for the target than under conditions that lead to poor memory for the target. Furthermore, we hypothesized that a substantial correlation between accuracy and confidence will be observed if, because of variations in conditions, there is considerable variability across participants in ability to identify the target. Consistent with these hypotheses, manipulations that affected accuracy also affected confidence in the same direction, and when data were collapsed across conditions the accuracy-confidence correlation was substantial (mean r = .59).     

Visual word recognition of three-letter words as derived from the recognition of the constituent letters

Word recognition is one of the basic processes involved in reading. In this connection, a model for word recognition is proposed consisting of a perceptual and a decision stage. It is supposed that, in the perceptual stage, the formation of possible words proceeds by separate identification of each of the letters of the stimulus word in their positions. Letter perception is taken to be conditional on position because of interaction effects from neighboring letters. These effects are dependent on both position in the word and retinal eccentricity, which are of particular relevance in reading. The letter-based approach rests on the strong relationship between the results from single-letter recognition in meaningless strings and in real words. Next, in the decision step, the many alternatives generated in the perceptual stage are matched with a vocabulary of real words. It is supposed that the final choice from among the remaining words is made in accordance with the constant ratio rule; frequency effects are not separately incorporated in the model. All predictions of the model are generated by means of data from earlier experiments. Despite being not optimally suited for this purpose, the predictions compare favorably with responses in word-recognition experiments.     

On the Closure Properties of the Class of Full G-models of a Deductive System

In this paper we consider the structure of the class FGModS of full generalized models of a deductive system S from a universal-algebraic point of view, and the structure of the set of all the full generalized models of S on a fixed algebra A from the lattice-theoretical point of view; this set is represented by the lattice FACS_s A of all algebraic closed-set systems C on A such that (A, C) ε FGModS. We relate some properties of these structures with tipically logical properties of the sentential logic S. The main algebraic properties we consider are the closure of FGModS under substructures and under reduced products, and the property that for any A the lattice FACS_s A is a complete sublattice of the lattice of all algebraic closed-set systems over A. The logical properties are the existence of a fully adequate Gentzen system for S, the Local Deduction Theorem and the Deduction Theorem for S. Some of the results are established for arbitrary deductive systems, while some are found to hold only for deductive systems in more restricted classes like the protoalgebraic or the weakly algebraizable ones. The paper ends with a section on examples and counterexamples. Dedicated to the memory of Willem Johannes Blok