Decision-Making About Inherited Cancer Risk: Exploring Dimensions of Genetic Responsibility

Since genetic information has implications for family members, some choices about genetic risk may be influenced by perceptions of responsibility to relatives. Drawing upon 25 semi-structured interviews with test recipients in Canada, this study explored decisions about inherited breast-ovarian and colon cancer. Qualitative data analysis revealed the pervasive significance of genetic responsibility in test decisions. We highlight three dimensions of genetic responsibility: 1) to know about the self for self; 2) to know about the self for others; 3) to know about the self to oblige others to know. It is argued that these dimensions of genetic responsibility have implications for test decisions, family relationships and other family members’ desire to know (or not know) and to act (or not act) with respect to their own genetic risk. In particular, genetic responsibility may play out as a framing of a relative’s moral obligation to know their risk that could obviate any interest they might have in not knowing. We conclude that perceptions of responsibility to—and of−other family members be thoroughly explored in genetic counseling sessions.     

Constraints on enhanced extinction resulting from extinction treatment in the presence of an added excitor

Three Pavlovian fear conditioning experiments with rats as subjects explored the effect of extinction in the presence of a concurrent excitor. Our aim was to explore this particular treatment, documented in previous studies to deepen extinction, with novel control groups to shed light on the processes involved in extinction. Relative to subjects extinguished on the target CS alone, Experiments 1 and 2 found across a range of parameters that any appreciable effect of facilitated extinction due to the concurrent excitor was submerged by generalization decrement going from extinction to testing. In Experiment 3 we used different durations for the target and concurrent stimuli in order to discourage configuring and an ABC renewal design to increase sensitivity, and observed diminished renewal resulting from extinction in the presence of a second excitor. Our findings suggest that there are distinct limits to the observation of enhanced extinction in the presence of an excitor and identifies some of the sources of these limitations.     

Primary qualities, secondary qualities and the truth about intention

In this paper I will argue that Crispin Wright’s defence of the claim that the truth about intention is judgement-dependent is unstable because it can serve also to establish that the truth about shape is judgement-dependent, thereby violating his constraint that in developing the distinction between judgement-independent and judgement-dependent subject matters we have to be driven by the assumption that colour and shape will fall on different sides of the divide.     

Research in Applied Ethics: Problems and Perspectives

The last few decades have seen a dramatic increase in concern with matters of ethics in all areas of public life. This ‘applied turn’ in ethics raises important issues not only of focus, but also of methodology. Sometimes a moral end or moral feature is designed into an institution or technology; sometimes a morally desirable outcome is the fortuitous, but unintended, consequence of an institutional arrangement or technological invention. If designing-in ethics is the new methodological orientation for applied ethics, globalisation is providing many of the practical ethical problems upon which to deploy this methodology. This is a revised version of an article that was presented at the 2007 Applied Ethics Conference in Sapporo, Japan, hosted by the University of Hokkaido. Thanks to Jeroen van den Hoven for the key idea of ‘designing-in-ethics’.     

Different patterns of contingent stimulation differentially affect attention span in prelinguistic infants

The ability to sustain attention influences different domains including cognitive, motor, and communicative behavior. Previous research has demonstrated how an infant's parent can influence sustained attention. The purpose of our study was to expose infants systematically to both sensitive and redirective patterns of behavior to examine how unfamiliar individuals could influence attention. Results revealed infants changed their patterns of looking with the unfamiliar individuals. Infants had longer durations of sustained attention when interacting with a sensitive unfamiliar individual who followed into their attentional focus as opposed to an intrusive person who led their attentional focus. This study demonstrates that infants discriminate patterns of contingency to persons seen for only a short period of time broadening the range of potential mentors for learning.     

KILLING, SELF-DEFENSE, AND BAD LUCK

This essay argues on behalf of a hybrid theory for an ethics of self-defense understood as the Forfeiture-Partiality Theory. The theory weds the idea that a malicious attacker forfeits the right to life to the idea that we are permitted to prefer one's life to another's in cases of involuntary harm or threat. The theory is meant to capture our intuitions both about instances in which we can draw a moral asymmetry between attacker and victim and cases in which we cannot. I develop the theory by attending to instances of intentional, villainous harm and instances of involuntary danger—the latter of which are a matter of bad luck. I call some bad luck cases "Interpersonal Lottery Conflicts." These cases refer to potentially lethal conflicts into which parties are thrown as victims of circumstance. Although neither party has a moral advantage over another, that fact does not preclude permissible self-defense.     

Is the Narcissistic Personality Inventory still relevant? A test of independent grandiosity and entitlement scales in the assessment of narcissism

Some scholars have called for the replacement of the Narcissistic Personality Inventory (NPI) with more narrow scales measuring grandiosity and entitlement instead. In the current study, the authors examined the relations among the NPI and measures of grandiosity and entitlement, as well as in relation to a measure of the Five-Factor Model (FFM). The NPI manifested significant correlations with the alternative scales of entitlement and grandiosity and relatively similar patterns of correlations with the FFM traits. Of note, the NPI manifested significant incremental validity in the prediction of several FFM traits that are central to the conceptualization of narcissism. These findings suggest that some caution must be used before assuming that these lower-order scales can be used to replace the NPI in the assessment of narcissism.     

Asynchrony in discrete bimanual aiming: Evidence for visual strategies of coordination

The bimanual coupling literature supposes an inherent drive for synchrony between the upper limbs when making discrete bimanual movements. The level of synchrony is argued to be task dependent, reliant on the visual demands of the two targets, and the result of a complex pattern of hand and eye movements (Bingham, Hughes, & Mon-Williams, 2008 ; Riek, Tresilian, Mon-Williams, Coppard, & Carson, 2003 ). However, recent work by Bruyn and Mason ( 2009 ) suggests that temporal coordination is not solely influenced by visual saccades. In this experimental series, a total of 8 participants performed congruent movements to targets either near or far from the midline. Targets far from the midline, requiring a visual saccade, resulted in greater terminal asynchrony. Initial and terminal asynchrony were not consistent, but linked to the task demands at that stage of the movement. If the asynchrony evident at the end of a bimanual movement is due to a complex pattern of hand and eye movements then the removal of visual feedback should result in an increase in synchrony. Sixteen participants then completed congruent and incongruent bimanual aiming movements to near and/or far targets. Movements were made with or without visual feedback of hands and targets. Analyses revealed that movements made without visual feedback showed increased synchrony between the limbs, yet movements to incongruent targets still showed greater asynchrony. We suggest that visual constraints are not the sole cause of asynchrony in discrete bimanual movements.     

Sustaining and Expanding Systems of Care to Provide Mental Health Services for Children, Youth and Families Across America

The Substance Abuse and Mental Health Services Administration has been instrumental in supporting the development and implementation of systems of care to provide services to children and youth with serious mental health conditions and their families. Since 1993, 173 grants have been awarded to communities in all 50 states, Puerto Rico, Guam, the District of Columbia, and 21 American Indian/Alaska Native communities. The system of care principles of creating comprehensive, individualized services, family-driven and youth-guided care and cultural and linguistic competence, supported by a well-trained and competent workforce, have been successful in transforming the field of children's mental health and facilitating the integration of child-serving systems. This approach has achieved positive outcomes at the child and family, practice and system levels, and numerous articles have been published using data collected from system of care communities, demonstrating the effectiveness of this framework. This article will describe lessons learned from implementing the system of care approach, and will discuss the importance of expanding and sustaining systems of care across the country.