Temporal associations and prior-list intrusions in free recall

When asked to recall the words from a just-presented target list, subjects occasionally recall words that were not on the list. These intrusions either appeared on earlier lists (prior-list intrusions, or PLIs) or had not appeared over the course of the experiment (extra-list intrusions). The authors examined the factors that elicit PLIs in free recall. A reanalysis of earlier studies revealed that PLIs tend to come from semantic associates as well as from recently studied lists, with the rate of PLIs decreasing sharply with list recency. The authors report 3 new experiments in which some items in a given list also appeared on earlier lists. Although repetition enhanced recall of list items, subjects were significantly more likely to make PLIs following the recall of repeated items, suggesting that temporal associations formed in earlier lists can induce recall errors. The authors interpret this finding as evidence for the interacting roles of associative and contextual retrieval processes in recall. Although contextual information helps to focus recall on words in the target list, it does not form an impermeable boundary between current- and prior-list experiences.     

Anisomycin infused into the hippocampus fails to block "reconsolidation" but impairs extinction: the role of re-exposure duration

Recent studies have reported new evidence consistent with the hypothesis that reactivating a memory by re-exposure to a training context destabilizes the memory and induces "reconsolidation." In the present experiments, rats' memory for inhibitory avoidance (IA) training was tested 6 h (Test 1), 2 d (Test 2), and 6 d (Test 3) after training. On Test 1 the rats were either removed from the shock compartment immediately after entry or retained in the shock context for 200 sec, and intrahippocampal infusions of the protein synthesis inhibitor anisomycin (75 microg/side) were administered immediately after the test. Anisomycin infusions administered after Test 1 impaired IA performance on Test 2 in animals given the brief re-exposure, but impaired extinction in animals exposed to the context for 200 sec. Rats with anisomycin-induced retention impairment on Test 2 demonstrated spontaneous recovery of retention performance on Test 3, whereas rats showing extinction on Test 2 showed further extinction on Test 3. The findings indicate that post-retrieval administration of anisomycin impairs subsequent retention performance only in the absence of extinction and that this impairment is temporary.     

On the likelihood ratio test in structural equation modeling when parameters are subject to boundary constraints

The authors show how the use of inequality constraints on parameters in structural equation models may affect the distribution of the likelihood ratio test. Inequality constraints are implicitly used in the testing of commonly applied structural equation models, such as the common factor model, the autoregressive model, and the latent growth curve model, although this is not commonly acknowledged. Such constraints are the result of the null hypothesis in which the parameter value or values are placed on the boundary of the parameter space. For instance, this occurs in testing whether the variance of a growth parameter is significantly different from 0. It is shown that in these cases, the asymptotic distribution of the chi-square difference cannot be treated as that of a central chi-square-distributed random variable with degrees of freedom equal to the number of constraints. The correct distribution for testing 1 or a few parameters at a time is inferred for the 3 structural equation models mentioned above. Subsequently, the authors describe and illustrate the steps that one should take to obtain this distribution. An important message is that using the correct distribution may lead to appreciably greater statistical power.     

The role of treatment acceptability in the initiation of treatment for ADHD

Approximately 50% of families of children with ADHD fail to pursue, or adhere to, recommended treatments. The present study examines parent ratings of the acceptability of pharmacological and behavioral treatments for ADHD and the relationships between these ratings and subsequent pursuit of treatment. Fifty-five families whose children received an evaluation for ADHD completed questionnaires and were contacted 3 to 4 months later to assess their pursuit of treatment. Consistent with previous research, parents rated behavior therapy as more acceptable than medication. Parent ratings of medication acceptability significantly predict pursuit of pharmacological treatment, whereas ratings of the acceptability of behavior therapy do not predict pursuit of this treatment. Preliminary analyses found that Caucasian parents' ratings of medication are significantly higher than those of non-Caucasian parents. Furthermore, Caucasian families were more likely to pursue a recommendation for pharmacological treatment than non-Caucasian families. The clinical and research implications of these results are considered.     

Variations in Anxiety and Depression as a Function of ADHD Subtypes Defined by DSM-IV: Do Subtype Differences Exist or Not?

Concerns have been raised about the ability of diagnostic criteria for attention-deficit/hyperactivity disorder (ADHD) to distinguish subtypes that are clearly distinct from each other with regard to clinical correlates. One area of concern is that research regarding differences in anxiety and depression as a function of ADHD subtype has produced discrepant findings. This study was designed to systematically evaluate whether the ADHD subtypes differ with regard to level of internalizing symptoms. From a large pool of children referred to an ADHD center based in a pediatric hospital, children were differentiated into three groups: ADHD, Combined Type (ADHD/COM); ADHD, Inattentive Type (ADHD/I); and a non-ADHD, comparison group (COMP). Parent- and child-report measures using both dimensional and categorical methods were used to assess internalizing symptoms. The results indicated that children with ADHD/COM and ADHD/I had similar levels of anxiety and depression. Subtype differences related to parent-reported depression were accounted for by group differences in level of externalizing problems. The results were discussed with regard to their implications for refining the criteria used to differentiate children with ADHD into subtypes.     

Muscarinic cholinergic influences in memory consolidation

The central cholinergic system and muscarinic cholinergic receptor (mR) activation have long been associated with cognitive function. Although mR activation is no doubt involved in many aspects of cognitive functioning, the extensive evidence that memory is influenced by cholinergic treatments given after training either systemically or intra-cranially clearly indicates that cholinergic activation via mRs is a critical component in modulation of memory consolidation. Furthermore, the evidence indicates that activation of mRs in the basolateral amygdala (BLA) plays an essential role in enabling other neuromodulatory influences on memory consolidation. Memory can also be affected by posttraining activation of mRs in the hippocampus, striatum and cortex. Evidence of increases in hippocampal and cortical acetylcholine (ACh) levels following learning experiences support the view that endogenous ACh release is involved in long-term memory consolidation. Furthermore, the findings indicating that mR drug treatments influence plasticity in the hippocampus and in sensory cortices strongly suggest that mR activation is involved in the storage of information in these brain regions.     

Assessing Culturally Different Students for Attention Deficit Hyperactivity Disorder Using Behavior Rating Scales

Behavior rating scales are commonly used in the assessment of attention deficit-hyperactivity disorder (ADHD). However, there is little information available concerning the extent to which scales are valid with culturally different students. This study explored the use of the ADHD-IV Rating Scale School Version with male Caucasian (CA) and African American (AA) students from ages 5 to 18 years. Teachers rated AA students higher on all symptoms across all age groups. LISREL analysis indicated that scale does not perform identically across groups. This was supported by the results of multidimensional scaling with suggested that there is a different relation between items across groups. Implications for research and practice are discussed.     

Development of the Critical Elements of Genetic Evaluation and Genetic Counseling for Genetic Professionals and Perinatologists in Washington State

We present a method for the development of consensus documents describing the components of genetic evaluation and genetic counseling for various diagnoses. These documents were developed to encourage consistency among genetic professionals in Washington State. Other possible uses of these documents are to provide information regarding genetic evaluations for health care practitioners and payers, and to assist in quality assurance and genetic training programs. A working group of six genetic professionals developed two templates for the critical elements of genetic evaluation and genetic counseling, for clinical (nonprenatal) and prenatal patients. The working group then completed prototype templates for several specific genetic disorders. The templates and prototypes were sent to interested genetic professionals and perinatologists who submitted a total of 76 draft critical elements (CE's) to the working group. At two statewide meetings, participating practitioners modified and unanimously approved the CE templates, then unanimously approved the 21 draft CEs that had been finalized in small group discussions. Approved CE's were distributed to genetic professionals and perinatologists within the state.     

Two effects of repetition: Support for a dual-process model of know judgments and exclusion errors

In three experiments, aremember/know recognition test (Experiments 1–2) and an exclusion test (Experiments 2–3) were used to examine effects of repeated study presentations. An effect of study repetition was obtained for remember but not know judgments, similar to results reported by Gardiner, Kaminska, Dixon, and Java (1996). Experiment 2 demonstrated the similarity between know responses and exclusion errors; neither was affected by repeated study presentations. In Experiment 3, a response deadline procedure was used to show that exclusion errors are the product of two opposing processes—recollection and familiarity—both of which are influenced by repetition. The interpretation of exclusion errors and know responses is shown to require a dual-process model that includes an assumption about the relationship between processes.     

Sex-role identity and separation-individuation pathology

The Mahlerian theory of childhood psychological development suggests that the same sex parenting of girls in the mother-child dyad predisposes women to experience specific difficulties in the separation-individuation (S-I) process (Mahler, Pine & Bergman, 1975). Pathological states in adulthood have been attributed to these S-I disturbances (Pine 1979; Kernberg 1980). However, this theory has never been empirically tested. In this study 53 subjects were assessed for adult manifestation of disturbance in the separation-individuation process using a self-report questionnaire (Separation-Individuation Inventory: Christenson & Wilson, 1985), In contrast to previous theoretical work, women showed significantly lower levels of disturbance in the separation-individuation process than did men. Assessment of sex-role identity (Bem Sex Role Inventory: Bem, 1981) showed no significant difference between overall sex-role identity of the male and female subjects. Individuals lacking any clear sex-role identity showed significantly higher levels of disturbance in the separation-individuation process than those with feminine, masculine or androgynous identity. These findings demonstrate the importance of considering sex-role identity as well as biological sex when describing some psychological characteristics and also demonstrate the importance of any sex-role acquisition, whether male or female, for psychological well-being.