Is eye movement dysfunction a biological marker for schizophrenia? A methodological review

There is a high prevalence of eye movement dysfunction (EMD) in persons with schizophrenia and their first-degree relatives. Studies addressing the prevalence, stability, familial transmission, and psychological correlates of EMD in persons from both psychiatric and general populations offer suggestive evidence that this abnormality may serve as a biological marker for schizophrenia. Although these findings are promising, their significance for elucidating the diagnostic bandwidth, pathophysiology, and genetics of this disorder remains to be determined. More precise characterization of ocular motility, perhaps when used in conjunction with global measures of pursuit adequacy, may be essential for clarifying the pathophysiological and genetic significance of EMD for schizophrenia. Recent research efforts are beginning to identify particular abnormalities that could serve as more specific biological markers for schizophrenia.     

The effect of inquiry on the Exner Comprehensive System

The effect of inquiry on the Comprehensive System was tested by scoring 130 protocols of patients and normals with and without inquiry. The absence of inquiry significantly reduced the means for Developmental Quality-vague (DQv), Form Quality-unusual (FQu), the sum of color responses (SumC), the sum of shading responses (Sum Shading), and the weighted thought disorder measure (W Sum6 SP SC), but significantly increased pure form (F). The effect for W Sum6 SP SC was strongest for schizophrenic protocols. Liberalized scoring rules were established in an attempt to restore the interpretative validity of the scoring categories distorted by the lack of inquiry. The new rules significantly improved the accuracy of color and shading categories, but did not improve the special scores measure of thought disorder.     

Literalism as a marker of hypnotic "trance": disconfirming evidence

The responses given by highly hypnotizable, hypnotic subjects and those of unhypnotizable subjects who simulated hypnosis to questions of the type, "Do you mind telling me your name?" and "Do you mind standing up?" were contrasted. The purpose was to examine Erickson's (1980) assertion that literalism (answering "yes" or "no" verbally or nonverbally without any cognitive elaboration) is a marker of hypnotic "trance." Simulators exhibited a greater rate of literalism than hypnotic "virtuosos" (i.e., extreme scorers on both group and individual hypnotizability measures). Hypnotized subjects and nonhypnotized subjects approached in the campus library responded comparably. Because less than a third of hypnotic virtuosos responded literally, our results strongly refuted Erickson's assertion that literalism is a cognitive feature of hypnosis.     

The "REST" program: a new treatment system for the oppositional defiant adolescent

This study compared the REST (Real Economy System for Teens) program with traditional talk therapy in the treatment of oppositional defiant adolescents. The REST program uses rules for five target behaviors: room care, personal hygiene, completion of chores, abusiveness, and safety violations. Objective measures and subjective parental ratings were taken. Twenty-five adolescents were assigned to each therapy group. In the REST program the adolescent was provided with only food and shelter. The adolescent had to earn money through the REST allowance program to pay for everything else. Earning the allowance was made contingent upon compliance with all rules for the five target behaviors. The results showed significantly greater improvement on all target behaviors for the REST program than for traditional therapy. In addition, parents of adolescents in the REST group reported that their adolescents seemed happier, more relaxed, and closer to them.     

Measurement of visual aftereffects and inferences about binocular mechanisms in human vision

There is conflicting evidence concerning the characteristics of binocular channels in the human visual system with respect to the existence of a 'pure' binocular channel that responds only to simultaneous stimulation of both eyes. Four experiments were conducted to resolve these discrepancies and to evaluate the evidence for the existence of such an exclusive binocular channel. In the first three studies, tilt aftereffects were measured after monocular adaptation. The relative sizes of the direct, interocularly transferred, and binocular aftereffects were not influenced by the configuration of the adapting pattern (experiment 1), or by the eye used for adaptation (experiment 2). There were also consistent interobserver differences in the relative sizes of the aftereffect seen after monocular adaptation (experiment 3). Taken together, these data raise questions about the appropriateness of a monocular adaptation paradigm for evaluating the presence of a pure binocular channel in observers with normal binocular vision. In experiment 4, in which the paradigm of alternating monocular adaptation was used, data were obtained that are consistent with the presence of a pure binocular channel.     

Dentists' voice control: effects on children's disruptive and affective behavior

Voice control, a punishment technique based on loud commands, has been used widely in pediatric dentistry. This study examined whether (a) loudness is a necessary component of the technique, (b) voice control actually reduces children's disruptive behavior, and (c) after treatment, children's negative affect increases. Subjects were forty 3 1/2- to 7-year-olds who posed potential behavior problems and who were scheduled for cavity restoration. Children were assigned randomly to either loud- or normal-voice groups. Children who were assigned to either group but who were not disruptive formed a nonexperimental control group. Prior to and after treatment, children reported their feelings using the Self-Assessment Mannequin. Disruptive behavior was scored using the Behavior Profile Rating Scale. Results indicated that, following loud, but not normal voice commands, children reduced their disruptive behavior (p less than .004) and self-reported lower arousal (p less than .09) and greater pleasure (p less than .10). Theoretical and practical implications of these findings are discussed.     

Attention and disordered eating behavior: II. Disattention to turbulent inner sensations as a risk factor in the development of anorexia nervosa

The Slade model for development of anorexia nervosa proposes that the female may seek success and control in her life by pursuing a thin body through dieting when faced with serious personal problems. Extending upon this model, the present program of research has sought to identify those characteristics of women generally at-risk for anorexia nervosa that would make dieting behavior especially successful, permitting the progression from food restraint into food aversion. The present studies considered whether heightened and stress-related inner stimulation could interfere with the at-risk woman's sensitivity to hunger sensations, thereby decreasing her motivation to eat. A series of analyses conducted within two studies indicated: (1) a relationship between elevated daily stress, concern over being over-whelmed by inner feelings, and a loss of discrimination regarding sources of inner feelings, (2) a tendency to narrow attentional focus when overloaded with excessive internal stimulation, and (3) diminished sensitivity to hunger sensations for women generally at-risk for anorexia nervosa given a narrowed attentional focus.     

Dissociations between procedural and episodic memory: effects of time and aging

The issue of multiple memory systems is explored. Young and older adults (mean ages = 20 and 71, respectively) named pictures and were tested immediately, 1, 7, or 21 days later. Episodic memory (recognition) for pictures was significantly lower in older relative to young adults and declined systematically across all retention intervals in both age groups. In contrast, procedural memory (repetition priming in picture naming) revealed no reliable age differences. In both age groups, priming declined within the first 24 hr, but unlike recognition, there was no further decrement from 1 to 21 days. There were also within-subject dissociations: The magnitude of priming was equivalent for remembered and forgotten items, and the relation between recognition and priming across intervals was nonmonotic, revealing a reversed association. The findings were interpreted within a multiple-memory-systems framework.     

Perceived parental inconsistency as a factor in the emotional development of behaviour-disordered children

55 English-speaking institutionalized adolescents (37 boys and 18 girls between ages of 14 and 19 yr.) were given questionnaires measuring perceived parental inconsistency and different components of emotional development. Canonical correlation analysis indicated that a significant proportion (51%) of the variation in emotional adjustment was accounted for by parental inconsistency. It is suggested that the efficiency of using parents as agents of change for their behaviour-disordered children can be enhanced by including theory on parenteral inconsistency in program content.