雷替曲塞治疗老年晚期结直肠癌的疗效分析

比较雷替曲塞与5-氟尿嘧啶联合奥沙利铂治疗老年晚期结直肠癌的临床疗效及生存分析。经病理明确诊断的老年晚期结直肠癌患者42例分为A、B两组,分别采用雷替曲塞和5-氟尿嘧啶／亚叶酸钙联合奥沙利铂方案化疗,观察两组疗效、不良反应及生存分析。结果A、B两组患者有效率接近,无统计学差异。A、B组疾病进展时间分别是7．5个月和5．...     

The Body in Spiritual Exercise: A Comparative Study between Epictetan Askēsis and Early Buddhist Meditation

The paper explores the role of body in Epictetus’s Discourse and Buddhist Satipa??hāna Sutta and underscores the importance of embodied practice in Epictetan askēsis (‘training or exercise’). It argues that the important but unrecognized role of the body in Epictetan askēsis can be better understood if we introduce in some perspectives of early Buddhism. From the angle of spiritual exercise, early Buddhism maintains that the meditator ought to experience the body directly and contemplate the body as an impermanent physical object, and not identify oneself with it. And based on the insight into the reality of the body and the cultivation of bodily awareness, the meditator can detach himself from the transient phenomenon and remove the unwholesome states of mind. Similarly, for Epictetus, by training our impression on the body and regarding the body as an indifferent thing but not the true self, one may successfully attain the truth of the body conditioned in various social contexts and then realize detachment and freedom. Therefore, in both early Buddhist meditation and Epictetan askēsis, the embodied practice of contemplating the body as it actually is, is also a spiritual exercise to understand the phenomenal world and detach from external things and to examine and tranquilize the internal world.     

经验、材料性质及加工水平对虚假记忆的影响

本实验采用DRM研究范式,考察经验、材料性质和加工水平三个方面对虚假记忆的影响。实验首次采用句子的方式呈现,给被试提供符合经验和不符合经验的句子进行学习和再认。实验结果显示,三个因素对虚假记忆的影响都是显著的,其中,经验是导致虚假记忆产生的主导因素,加工深度同经验之间以及材料性质同经验之间的交互作用均存在显著的交互作用。     

学习不良儿童的家庭心理环境,父母教养方式及其与社会性发展的关系

从２３０８名１０—１５岁儿童中选取４２９名被试的研究结果表明．一般儿童的家庭心理环境、父母教养方式大大优于学习不良儿童,这些家庭资源与学习不良儿童的社会交往、自我概念和社会行为等有着密切的联系,说明家庭心理环境、父母教养方式对学习不良儿童社会性发展产生着重要作用。     

Unconscious preparation: Effects of prime visibility on semantic generalization of task priming

Studies found that subliminal primes can be associated with specific tasks to facilitate task performance, and such learning is highly adaptive and generalizable. Meanwhile, conditioning studies suggest that aversive/reward learning and generalization actually occur at the semantic level. The current study shows that prime–task associations can also be generalized to novel word/neighbour primes from the same semantic category, and this occurs without contingency awareness. Previous studies have counterintuitively suggested that both the learning of task priming and the semantic priming of word neighbours depend on the lack of visibility. Here, we show that semantic generalization indeed depends on reduced visibility, but cannot occur subliminally. The current study shows for the first time that semantic learning and generalization can occur without any emotional or motivational factors, and that semantic priming can occur for arbitrary-linked stimuli in a context completely devoid of semantics.     

急性应激损害对威胁刺激的注意解除

急性应激会增强个体对威胁刺激的注意偏向,但急性应激是增强了对威胁刺激的注意定向还是损害了对威胁刺激的注意解除还不清楚。本研究采用社会评估冷压任务和点探测任务,结合事件相关电位技术,考察急性应激对威胁刺激注意偏向影响的认知机制。在进行社会评估冷压任务后,应激组个体的状态焦虑和皮质醇浓度显著升高。在注意偏向中,应激组对威胁刺激的注意解除比控制组更慢,应激组和控制组在对威胁刺激的注意定向上无显著差异。ERP结果上,威胁刺激诱发应激组比控制组产生了更负的SPCN,在N2pc上没有显著差异。应激组和控制组皮质醇增量的差异和N2pc、SPCN的组间差异均有显著正相关。这些结果说明,急性应激增强对威胁刺激的注意偏向是因为其损害个体对威胁刺激的注意解除,这可能是因为急性应激损害了与注意解除相关的额-顶网络的功能所致。     

Resting Heart Rate,Vagal Tone,and Reactive and Proactive Aggression in Chinese Children

Abundant research conducted in Western contexts has shown that biological risk factors such as low resting heart rate (HR) might be related to childhood aggression. However, it was unclear (1) how resting HR, as well as other markers of cardiac functions such as resting vagal tone, may be related to subtypes of aggression such as reactive and proactive aggression, and (2) whether the HR-aggression relation can be replicated in non-Western contexts. Therefore, this study examined the concurrent and prospective relations between resting HR, vagal tone, and Chinese children’s reactive and proactive aggression. Participants were 183 children (M age?=?7.64 years, 91 girls) recruited from an elementary school in Zhenjiang, PRC. Children’s resting HR and vagal tone were assessed in the second grade (T1). Teachers rated children’s reactive and proactive aggression in the second (T1) and fourth grade (T2). Results showed that lower resting HR at T1 was associated with higher reactive and proactive aggression at T1 and T2, and higher vagal tone was associated with lower HR, which in turn was related to higher reactive and proactive aggression at T1 and T2. Lower vagal tone was directly related to higher reactive but not proactive aggression at T1 and T2, whereas lower HR was related to higher reactive aggression at T2 for children with low or moderate vagal tone but was not for children with high vagal tone. These psychophysiological findings from a non-Western context add additional support for both similarities and differences between reactive and proactive aggression in childhood.     

Managing the interactions between multiple identities in inter-organizational collaborations: an identity work perspective

Inter-organizational collaboration (IOC) research considers the achievement of a collaborative identity as a key enabler of a successful collaboration. As a result, little has been said about the interactions between collaborative and non-collaborative identities. We build on narrative identity work and positioning theory, to explore how collaboration partners engage in identity work positioning to manage the interactions of the multiple identities emerging through the process of collaboration as they try to accomplish collaborative work. We illustrate this process through a qualitative longitudinal study of an educational partnership in Greece. Our analysis shows how IOC partners manage the interactions between collaborative and non-collaborative identities by positioning themselves, and others, in narratives of collaboration as part of their daily identity work when responding to emerging collaborative needs. Our research extends our current understanding of identity work processes in IOCs by demonstrating the paradoxical nature of the collaboration, which requires relying on both collaborative and non-collaborative identities for the successful achievement of aims. We therefore suggest that identity tensions should not be resolved but rather managed, since they enable partners to respond creatively to contextual organizational changes and make sense of the collaboration as it happens.     

Development of the ability to combine visual and acoustic information in working memory

Presentation of two kinds of materials in working memory (visual and acoustic), with the requirement to attend to one or both modalities, poses an interesting case for working memory development because competing predictions can be formulated. In two experiments, we assessed such predictions with children 7–13 years old and adults. With development, the ability to hold more information in the focus of attention could lead to an increase in the size of the trade‐off between modalities; if attention can hold A items during unimodal‐attention trials, then on average attention should hold A/2 of those same items during bimodal‐attention trials. If A increases with age, so would the dual‐task cost, A/2. The results clearly ruled out that possibility. It was the modality‐ or code‐specific components of working memory that improved with age and not the central component. We discuss various mechanisms that could have produced these results, including alternative attention‐based mechanisms. The findings point to a rich field for continued research.