Language deficits, localization, and grammar: evidence for a distributive model of language breakdown in aphasic patients and neurologically intact individuals.

Selective deficits in aphasic patients' grammatical production and comprehension are often cited as evidence that syntactic processing is modular and localizable in discrete areas of the brain (e.g., Y. Grodzinsky, 2000). The authors review a large body of experimental evidence suggesting that morpho-syntactic deficits can be observed in a number of aphasic and neurologically intact populations. They present new data showing that receptive agrammatism is found not only over a range of aphasic groups, but is also observed in neurologically intact individuals processing under stressful conditions. The authors suggest that these data are most compatible with a domain-general account of language, one that emphasizes the interaction of linguistic distributions with the properties of an associative processor working under normal or suboptimal conditions.     

An on-line task for contrasting auditory processing in the verbal and nonverbal domains and norms for younger and older adults

Contrasting linguistic and nonlinguistic processing has been of interest to many researchers with different scientific, theoretical, or clinical questions. However, previous work on this type of comparative analysis and experimentation has been limited. In particular, little is known about the differences and similarities between the perceptual, cognitive, and neural processing of nonverbal environmental sounds and that of speech sounds. With the aim of contrasting verbal and nonverbal processing in the auditory modality, we developed a new on-line measure that can be administered to subjects from different clinical, neurological, or sociocultural groups. This is an on-line task of sound to picture matching, in which the sounds are either environmental sounds or their linguistic equivalents and which is controlled for potential task and item confounds across the two sound types. Here, we describe the design and development of our measure and report norming data for healthy subjects from two different adult age groups: younger adults (18–24 years of age) and older adults (54–78 years of age). We also outline other populations to which the test has been or is being administered. In addition to the results reported here, the test can be useful to other researchers who are interested in systematically contrasting verbal and nonverbal auditory processing in other populations.     

Order of report and processing in tachistoscopic recognition

Two groups of 12 Ss were shown tachistoscopically 4 letters and 4 numbers. Within these alpha-numeric sequences, three variables were systematically manipulated: grouping of items, initial item, and familiarity of the letter sequences. One group of Ss reported first letters then numbers from each sequence; the other group reported numbers then letters. The results indicated that grouping, redundancy, and order of report had significant effects on letter accuracy but not on number accuracy. These effects were interpreted in terms of processing, particularly the use of spatial and identity information during recognition.     

Processing time for naming and categorization of letters and numbers

A reaction-time experiment was carried out to examine the relationship between naming and categorization. Ss were shown one item at a time and asked either to name the item or to categorize the item as a letter or number. The size of the stimulus set was varied systematically across Ss. Naming time increased as the stimulus set size increased; categorization time could be predicted by the time required for naming, plus a constant. These results were interpreted as indicating that naming must precede categorization.     

Maintenance and generalization of a semantic rehearsal strategy in educable mentally retarded children

Two groups of 11- to 12-year-old educable mentally retarded children, equated on the basis of a free recall pretest, were given a series of lists for free recall. Approximately half the subjects were trained in the use of a strategy designed to induce deeper level semantic encoding and the discovery of categorical relationships and half constituted a “no-training” control group with standard free recall instructions. The subjects received either related or unrelated lists during the training phase and related or unrelated lists during two post-tests, immediately following and 1 week after training. There was evidence not only that the semantic strategy was maintained over the 1-week delay, but that it also generalized to word lists unlike those used during training. The degree of generalization was greater for those subjects receiving related lists during training.     

Dependence on Visual Feedback During Motor Skill Learning in Alzheimer's Disease

Three experiments examined the role of visual feedback on the performance of a fine motor task, namely the rotary pursuit, in patients with Alzheimer's disease (AD) and healthy older adults. After extensive practice tracking a fully visible target, participants in Experiments 1 and 2 were tested under restricted vision (RV) conditions. In both experiments, the two groups showed a drop in performance when vision was restricted, with AD patients showing a significantly larger decline. Tracking improved significantly in normal controls, but not AD patients across the RV trials after the initial drop. When difficulty of the rotary pursuit task was manipulated in Experiment 3 without restricting vision, AD patients and normal controls showed identical patterns of performance. Consequently, it could be concluded that AD patients in the first two experiments were relying more heavily on visual information for accurate performance of the tracking task than their healthy peers.     

Religiosity for Promotion of Behaviors Likely to Reduce New HIV Infections in Uganda: A Study Among Muslim Youth in Wakiso District

The study was done to determine the association between religiosity and behaviors likely to reduce new HIV infections among 1,224 Muslim youth. Respondents with Sujda, the hyperpigmented spot on the forehead due to prostration during prayers, were more likely to abstain from sex, be faithful in marriage, and avoid alcohol and narcotics. Males wearing a Muslim cap were more likely to abstain from sex and avoid alcohol and narcotics. Females wearing the long dress (Hijab) were also more likely to avoid alcohol. This data should be used by stakeholders in promoting behaviors likely to reduce new HIV infections among Muslims.     

Self and partner personality and responses to relationship threats

Two studies examined the relations between three different types of jealousy and personality characteristics of self and partner in two large heterogeneous community samples of heterosexual couples (459 and 230 couples, respectively). It was expected that partners would resemble each other to some extent in both the experience of different types of jealousy and personality characteristics, and that self-reported levels of neuroticism (+) and extraversion (−) would be related to higher levels of jealousy. Moreover, it was expected that partner extraversion would be related positively to levels of jealousy, and that similarity with regard to personality characteristics would be related to lower levels of jealousy. Results largely supported our expectations with regard to both partner similarity and self-reported personality characteristics. However, our expectations with regard to partner extraversion and similarity were not supported.     

Neuroticism and extraversion are associated with amygdala resting-state functional connectivity

The personality traits neuroticism and extraversion are differentially related to socioemotional functioning and susceptibility to affective disorders. However, the neurobiology underlying this differential relationship is still poorly understood. This discrepancy could perhaps best be studied by adopting a brain connectivity approach. Whereas the amygdala has repeatedly been linked to neuroticism and extraversion, no study has yet focused on the intrinsic functional architecture of amygdala-centered networks in relation to both traits. To this end, seed-based correlation analysis was employed to reveal amygdala resting-state functional connectivity (RSFC) and its associations with neuroticism and extraversion in 50 healthy participants. Higher neuroticism scores were associated with increased amygdala RSFC with the precuneus, and decreased amygdala RSFC with the temporal poles, insula, and superior temporal gyrus (p < .05, cluster corrected). Conversely, higher extraversion scores were associated with increased amygdala RSFC with the putamen, temporal pole, insula, and several regions of the occipital cortex (p < .05, cluster corrected). The shifts in amygdala RSFC associated with neuroticism may relate to the less-adaptive perception and processing of self-relevant and socioemotional information that is frequently seen in neurotic individuals, whereas the amygdala RSFC pattern associated with extraversion may relate to the heightened reward sensitivity and enhanced socioemotional functioning in extraverts. We hypothesize that the variability in amygdala RSFC observed in the present study could potentially link neuroticism and extraversion to the neurobiology underlying increased susceptibility or resilience to affective disorders.