Reproductive Health CHOICES for Young Adults with Sickle Cell Disease or Trait: Randomized Controlled Trial Outcomes over Two Years

Interventions to assist reproductive health decision-making in populations affected by sickle cell disease (SCD) or trait (SCT) lack proven efficacy over time. Our aim was to compare effects of CHOICES, a Web-based multimedia education program on implementing informed reproductive plans, and usual care education (e-Book) on reproductive knowledge, intention, and behavior over 24 months. We randomized 234 participants with SCD (n?=?138) or SCT (n?=?96) (age 18–35 years, 35 % male, 94 % African American) to CHOICES and e-Book groups. Participants completed a sickle cell-specific reproductive measure before and four times after the intervention (6, 12, 18 and 24 months). Compared to the e-Book group the CHOICES group had significantly more improvement in knowledge over time (p?=?.004) but not intention (p?=?.18) or behavior (p?=?.69). At baseline, 114 (48.7 %) participants reported having partners who would not put the couple at risk for their children inheriting SCD. Of the 116 (49.6 %) at-risk participants, a higher poroportion of those who were in the CHOICES group chose partners that reduced their risk by the last visit than the e-Book group (p?=?.04). Study findings provide important insights for designing a national trial of the CHOICES intervention focusing on subjects whose partner status puts them at risk for having a child with SCD.     

Student-Athletes’ Views on <Emphasis Type="Italic">APOE</Emphasis> Genotyping for Increased Risk of Poor Recovery after a Traumatic Brain Injury

Use of apolipoprotein E genotyping to personalize the risk of a poor recovery after traumatic brain injury is complicated by the potential for genetic discrimination and the potential to reveal an increased risk for late onset Alzheimer’s disease. We developed a survey to gauge interest in testing among athletes participating in National Collegiate Athletic Association programs. Eight hundred and forty seven student-athletes were surveyed to determine their interest in genetic testing, their willingness to share the results of testing with parents, coaches and physicians, their concerns about privacy and/or discrimination, and their interest in genetic counseling. Nearly three quarters of respondents expressed some level of interest in testing, with the largest number describing themselves as ‘possibly interested’ (54.9 %, n = 463) and a smaller number describing themselves as ‘very interested’ (18.9 %, n = 159). Most student-athletes said that receiving secondary information about their risk for late-onset Alzheimer’s disease made them more likely to test (50.6 %, n = 426) rather than less likely to test (12.4 %, n = 104). Student-athletes were open to apolipoprotein E genotyping and willing to share test results with their parents, coaches and physicians. They did not anticipate that test results would impact their behavior or ability to play. Testing programs may be welcome but should provide clear information as to risks and benefits.     

Victims' emotional distress and preventive measures usage: Influence of crime severity,risk perception,and fear

The central thesis of this study is that crime victims' emotional distress, influenced by the severity of the offence experienced, impacts their propensity to utilize preventive measures via its influence on perceived risk of victimization and fear of crime. Path analysis was conducted to test a model of these relationships, utilizing data from a crime victimization survey conducted on the Caribbean Island, Trinidad, in 2015. Results suggest a direct predictive relationship between crime severity and emotional distress and indirect effects of emotional distress on preventive measures through risk perception and fear of crime. Findings were discussed in the context of prior research, comparability, and variances, and practical implications were noted.     

Feminism and Women's Autonomy: the Challenge of Female Genital Cutting

Feminist studies of female genital cutting (FGC) provide ample evidence that many women exercise effective agency with respect to this practice, both as accommodators and as resisters. The influence of culture on autonomy is ambiguous: women who resist cultural mandates for FGC do not necessarily enjoy greater autonomy than do those women who accommodate the practice, yet it is clear that some social contexts are more conducive to autonomy than others. In this paper, I explore the implications for autonomy theory of these understandings of the relation between culture, FGC, and women's agency. I review the range of worldwide FGC practices – including "corrective" surgery for "ambiguous genitalia" in Western cultures as well as the various initiation rites observed in some African and Asian cultures – and the diverse cultural rationales for different forms of FGC. I argue that neither latitudinarian, value-neutral accounts of autonomy nor restrictive, value-saturated accounts adequately explain women's agentic position with respect to FGC. I then analyze a number of educational programs that have enhanced women's autonomy, especially by strengthening their introspection, empathy, and imagination. Such programs, which engage women's autonomy skills without exposing them to autonomy-disabling cultural alienation, promote autonomy-within-culture. This understanding of autonomy as socially situated, however, entails neither endorsement of FGC nor resignation to its persistence.     

Language,cognition, and second language grammaticality judgments

In first language research, there appear to be two predominant positions relating metalinguistic awareness to language development. One suggests that since metalinguistic awareness is related to primary language acquisition (comprehension and production), general cognitive processes perform a limited role in metalinguistic awareness. The other suggests that since metalinguistic awareness is more closely related to secondary language acquisition (reading and writing), a greater role is assumed by general cognitive processes. There have been some indirect attempts to study the role of language and cognition with respect to second language grammaticality judgments. There is growing evidence that metalinguistic awareness is a reliable indicator of developing second language competence. Furthermore, it has been shown that language aptitude is significantly related to metalinguistic awareness. The present study was designed to investigate the statistical relationship between second language grammaticality judgments and selected cognitive and linguistic variables. The variables studied were second language proficiency, second language classroom achievement, first language reading competence, language aptitude, nonverbal intelligence, field dependence-independence, and a written grammaticality judgment test tapping the ability to recognize, and correct, deviance. Subjects were college students in advanced English-as-a-second-language classes. Multivariate statistical techniques were used to determine the relative contribution of linguistic and cognitive variables to the individual variation demonstrated by the learners in their ability to detect deviance in English. The results showed that second language proficiency, second language achievement in the classroom, and language aptitude were significant predictors of the subjects' ability to make grammaticality judgments. First language reading competence was significantly related to subjects' ability to correct deviance. These observations are discussed in the light of: (1) the relationship among cognition, language, and metalinguistic awareness, and (2) the role of metalinguistic awareness in second language acquisition and second language learning.