Enhancement of phonological memory following transcranial magnetic stimulation (TMS)

Phonologically similar items (mell, rell, gell) are more difficult to remember than dissimilar items (shen, floy, stap), likely because of mutual interference of the items in the phonological store. Low-frequency transcranial magnetic stimulation (TMS), guided by functional magnetic resonance imaging (fMRI) was used to disrupt this phonological confusion by stimulation of the left inferior parietal (LIP) lobule. Subjects received TMS or placebo stimulation while remembering sets of phonologically similar or dissimilar pseudo-words. Consistent with behavioral performance of patients with neurological damage, memory for phonologically similar, but not dissimilar, items was enhanced following TMS relative to placebo stimulation. Stimulation of a control region of the brain did not produce any changes in memory performance. These results provide new insights into how the brain processes verbal information by establishing the necessity of the inferior parietal region for optimal phonological storage. A mechanism is proposed for how TMS reduces phonological confusion and leads to facilitation of phonological memory.     

Aging effects on memory encoding in the frontal lobes

Functional magnetic resonance imaging (fMRI) was used to compare frontal-lobe activation in younger and older adults during encoding of words into memory. Participants made semantic or nonsemantic judgments about words. Younger adults exhibited greater activation for semantic relative to nonsemantic judgments in several regions, with the largest activation in the left inferior frontal gyrus. Older adults exhibited greater activation for semantic judgments in the same regions. but the extent of activation was reduced in left prefrontal regions. In older adults, there was a significant association between behavioral tests of declarative and working memory and extent of frontal activation. These results suggest that age-associated decreases in memory ability may be due to decreased frontal-lobe contributions to the initial encoding of experience.     

Linking Childhood Sexual Abuse and Early Adolescent Risk Behavior: The Intervening Role of Internalizing and Externalizing Problems

A robust literature links childhood sexual abuse (CSA) to later substance use and sexual risk behavior; yet, relatively little empirical attention has been devoted to identifying the mechanisms linking CSA to risky behavior among youth, with even less work examining such processes in boys. With the aim of addressing this gap in the literature, the current study examined the indirect effect of childhood sexual abuse (CSA; from age 2 to 12) trajectory group on risky behavior at age 14 (alcohol use & sexual intercourse) via the intervening role of caregiver-reported internalizing and externalizing problems at age 12. Analyses were conducted with a subsample of youth (n?=?657 sexual intercourse; n?=?667 alcohol use) from the Longitudinal Studies of Child Abuse and Neglect (LONGSCAN), a multisite prospective study of youth at risk for maltreatment. For boys and girls, there was an indirect effect from CSA to sexual intercourse through externalizing problems. The same pattern emerged for alcohol use, but only for girls. Findings did not support an indirect path through internalizing problems for either boys or girls for either outcome. Findings suggest more focal targets for prevention efforts aimed at maintaining the health and safety of maltreated boys and girls during the adolescent transition.     

Religion,Self Control,and Substance Use

Previous research has examined a number of mechanisms through which religion might have an indirect influence on substance use. One potential intervening mechanism that has received little empirical attention is self control. Using data from the National Longitudinal Study of Adolescent Health (Add Health) we (1) examine the association between religion and self control, (2) determine if self control mediates the effect of religiosity on substance use, and (3) determine if the effect of self control on substance use varies depending on adolescents’ religiosity. The results suggest that religious youth exhibit higher levels of self control. Also, self control partially mediates the effect of adolescents’ religiosity on marijuana use and drinking. The only evidence we find for an interaction between self control and religiosity suggests self control has a moderately greater effect on alcohol use among those of low, rather than medium or high, religiosity.     

Religious Involvement and Dynamics of Marijuana Use: Initiation,Persistence, and Desistence

Studies that examine the effects of adolescent religiosity on the initiation of, persistence in, and desistence from delinquency are rare. Yet, religion may differentially affect dimensions of delinquency in the early life course. Therefore, using data from the National Longitudinal Study of Adolescent Health (Add Health), we examine the relationship between measures of adolescent religion, as well as changes in religious involvement, and later patterns of marijuana use. We also examine the extent to which religious effects, if any, are mediated by key predictors of delinquency drawn from prominent criminological theories. The results suggest that the primary effect of religion on marijuana use is to prevent its initiation in the first place. Only part of religion's preventative effect on initiation is mediated by social bonds, delinquent peers, or self control. Although religious youth are less likely to ever use marijuana, adolescent religious involvement does not significantly predict desistence from marijuana use.     

Self-Control,Opportunity, and Substance Use

We examine the effect of self-control and opportunity on adolescent substance use. When theorizing about the role of opportunity, we believe the “sanction potential” of a given situation should be considered. Our results suggest the effect of self-control on substance use does not depend on the availability of substances in the home (high sanction potential), but friends’ substance use (low sanction potential) conditions the effect of self-control on adolescents’ smoking, drinking, and marijuana use. Therefore, adolescents with low self-control are more likely to use substances only when they are presented with attractive opportunities that are unlikely to lead to sanctions.     

Two Approaches to Reading the Historical Descartes

In this article I introduce a new reading of Jean-Paul Sartre's account of bad faith. The reading contrasts with previous accounts by denying that states of bad faith are exhausted by attitudes towards transcendence and facticity. Instead, I argue that bad faith can involve attitudes to many other aspects of the human being. I also respond to an argument which claims that affirmations of freedom are inconsistent with the motivations behind bad faith. The inconsistency is here resolved by demonstrating how in bad faith we can still affirm a restricted version of freedom which avoids us acknowledging the unpleasant aspects of our full freedom.     

Throwing in the dark: improved prediction of action outcomes following motor training without vision of the action

Traditional models of action understanding emphasise the idea that long-term exposure to a wide array of visual patterns of particular actions allows for effective action anticipation or prediction. More recently, a greater emphasis has been placed on the motor system’s role in the perceptual understanding and prediction of action outcomes. There have been attempts to isolate the contributions of visual and motor experience in action prediction, but to date, these studies have relied on comparisons of motor-visual experience to visual-only (observational) experience. We conducted a learning study, where visual experience was directly manipulated during practice. Novice participants practised throwing darts to 3 specific areas of a dartboard. A group trained without vision of their action, only feedback about the final landing position, significantly improved in their ability to predict the landing position of a thrown dart, from temporally occluded video clips. The performance of this ‘no-vision’ group did not differ from a Full-vision group and was significantly more accurate than an observation-only and a no-practice control group (with the latter two groups not improving pre- to post-practice). These results suggest that motor experience specifically modulates the perceptual prediction of action outcomes. This is thought to occur through simulative mechanisms, whereby observed actions are mapped onto the observer’s own motor representations.