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391.
392.
Obiang P Maubert E Bardou I Nicole O Launay S Bezin L Vivien D Agin V 《Neurobiology of learning and memory》2011,96(2):121-129
Although tissue type plasminogen activator (tPA) and brain derived neurotrophic factor (BDNF) have been extensively described to influence brain outcomes in a number of disorders, their roles during physiological aging are poorly investigated. In the present study, we investigated whether maintenance of mice in different environmental conditions could influence age-associated changes in hippocampal tPA expression and BDNF maturation in relation with modifications of their cognitive performances. Our data indicate that maintenance in enriched housing led to a reversal of age-associated decrease in expression of hippocampal tPA. A subsequent increase in the level of mature BDNF and an improvement in emotional and spatial memories were observed. Taken together, these data suggest that the tPA–BDNF axis could play a critical role in the control of cognitive functions influenced both by the age and housing conditions. 相似文献
393.
In an eye-tracking experiment, participants read sentences containing a monosyllabic (e.g., grain) or a disyllabic (e.g., cargo) five-letter word. Monosyllabic target words were skipped more often than disyllabic target words, indicating that syllabic structure was extracted from the parafovea early enough to influence the decision of saccade target selection. Fixation times on the target word when it was fixated did not show an influence of number of syllables, demonstrating that number of syllables differentially impacts skipping rates and fixation durations during reading. [corrected] 相似文献
394.
Depressive symptoms and cognitive decline are associated in older age, but research is inconsistent about whether one condition influences the development of the other. We examined the directionality of relations between depressive symptoms and perceptual speed using bivariate dual change score models. Assessments of depressive symptoms and perceptual speed were completed by 1,206 nondemented older adults at baseline, and after 2, 8, 11, and 15 years. After controlling for age, education, baseline general cognitive ability, and self-reported health, allowing depressive symptoms to predict subsequent change in perceptual speed provided the best fit. More depressive symptoms predicted subsequently stronger declines in perceptual speed over time lags of 1 year. 相似文献
395.
Three experiments investigated responding consistent with transitive class containment, a feature of hierarchical classification. Experiment 1 replicated key components of a preliminary attempt to model hierarchical classification (Griffee & Dougher, 2002) and tested for responding consistent with transitive class containment. Only 2 out of 5 participants showed the expected pattern. Experiment 2 tested whether repeated exposures to the Experiment 1 protocol would give rise to the expected pattern more reliably. None of 3 novel participants demonstrated the pattern. In Experiment 3, physically similar stimuli used in Experiments 1 and 2 were replaced across testing cycles by arbitrary stimuli. Transitive-class-containment-consistent responding was observed in all 3 novel participants. Implications, limitations and future research are discussed. 相似文献
396.
Three‐ to 4‐month‐old infants show asymmetric exclusivity in the acquisition of cat and dog perceptual categories. The cat perceptual category excludes dog exemplars, but the dog perceptual category does not exclude cat exemplars. We describe a connectionist autoencoder model of perceptual categorization that shows the same asymmetries as infants. The model predicts the presence of asymmetric retroactive interference when infants acquire cat and dog categories sequentially. A subsequent experiment conducted with 3‐ to 4‐month‐olds verifies the predicted pattern of looking time behaviors. We argue that bottom‐up, associative learning systems with distributed representations are appropriate for modeling the operation of short‐term visual memory in early perceptual category learning. 相似文献
397.
The paper explores certain phenomena which arise in stories, conversations, and human activity in general when the plans of two individuals are formed and carried out in an interactive situation. A notation system for representing interacting plans is introduced and applied in the analysis of a small portion of “Hansel and Gretel.” The analysis illustrates how a single actor plan can be modified by the needs of cooperative interaction with others and how cooperative interactive episodes can be transformed and used deceptively by one party in achieving his or her own covert goals. 相似文献
398.
Tomas Lenc Varghese Peter Caitlin Hooper Peter E. Keller Denis Burnham Sylvie Nozaradan 《Developmental science》2023,26(5):e13353
Music listening often entails spontaneous perception and body movement to a periodic pulse-like meter. There is increasing evidence that this cross-cultural ability relates to neural processes that selectively enhance metric periodicities, even when these periodicities are not prominent in the acoustic stimulus. However, whether these neural processes emerge early in development remains largely unknown. Here, we recorded the electroencephalogram (EEG) of 20 healthy 5- to 6-month-old infants, while they were exposed to two rhythms known to induce the perception of meter consistently across Western adults. One rhythm contained prominent acoustic periodicities corresponding to the meter, whereas the other rhythm did not. Infants showed significantly enhanced representations of meter periodicities in their EEG responses to both rhythms. This effect is unlikely to reflect the tracking of salient acoustic features in the stimulus, as it was observed irrespective of the prominence of meter periodicities in the audio signals. Moreover, as previously observed in adults, the neural enhancement of meter was greater when the rhythm was delivered by low-pitched sounds. Together, these findings indicate that the endogenous enhancement of metric periodicities beyond low-level acoustic features is a neural property that is already present soon after birth. These high-level neural processes could set the stage for internal representations of musical meter that are critical for human movement coordination during rhythmic musical behavior.
Research Highlights
- 5- to 6-month-old infants were presented with auditory rhythms that induce the perception of a periodic pulse-like meter in adults.
- Infants showed selective enhancement of EEG activity at meter-related frequencies irrespective of the prominence of these frequencies in the stimulus.
- Responses at meter-related frequencies were boosted when the rhythm was conveyed by bass sounds.
- High-level neural processes that transform rhythmic auditory stimuli into internal meter templates emerge early after birth.
399.
400.
Denis Mareschal Daisy Powell Gert Westermann Agnes Volein 《Infant and child development》2005,14(5):445-457
Young infants are very sensitive to feature distribution information in the environment. However, existing work suggests that they do not make use of correlation information to form certain perceptual categories until at least 7 months of age. We suggest that the failure to use correlation information is a by‐product of familiarization procedures that encourage infants to over encode individual exemplars rather than relations across exemplars. By changing the exemplar presentation regime to one in which exemplars are rapidly (2 s durations) and repeatedly presented we find that 4‐month‐olds can form perceptual categories on the basis of feature correlation information. In addition, this ability emerges rapidly between 114 and 134 days. We argue that the ability to process correlation information is present very early on but that the demonstration of that ability in categorization tasks is mediated by the demands of the task the infant is tested with. Copyright © 2005 John Wiley & Sons, Ltd. 相似文献