Impairment of syntax and lexical semantics in a patient with bilateral paramedian thalamic infarction

Bilateral vascular thalamic lesions are rare. Although a variety of neurobehavioral manifestations have been described, the literature is less documented with regard to accompanying linguistic disturbances. This article presents an in-depth neurolinguistic analysis of the language symptoms of a patient who incurred bilateral paramedian ischemic damage of the thalamus. In the post-acute phase of the stroke, a unique combination of transcortical sensory aphasia with syntactic impairment was found. Because of this atypical semiological association, additional analyses of spontaneous speech were performed. In spite of the typological affinity with the grammatic characteristic of marked simplification of syntax observed in Broca's aphasia, only a wordclass specific, lexical-semantic deficit for verbs was objectified. The hypothesis that lexical-semantic disturbances in our patient might result from a functional deafferentiation of both thalami with the frontal lobe is supported by: (1) associated neuropsychological deficits of frontal origin and (2) frontal-like behavioral disturbances.     

Phonological encoding in the silent speech of persons who stutter

The purpose of the present study was to investigate the role of phonological encoding in the silent speech of persons who stutter (PWS) and persons who do not stutter (PNS). Participants were 10 PWS (M=30.4 years, S.D.=7.8), matched in age, gender, and handedness with 11 PNS (M=30.1 years, S.D.=7.8). Each participant performed five tasks: a familiarization task, an overt picture naming task, a task of self-monitoring target phonemes during concurrent silent picture naming, a task of monitoring target pure tones in aurally presented tonal sequences, and a simple motor task requiring finger button clicks in response to an auditory tone. Results indicated that PWS were significantly slower in phoneme monitoring compared to PNS. No significant between-group differences were present for response speed during the auditory monitoring, picture naming or simple motor tasks, nor did the two groups differ for percent errors in any of the experimental tasks. The findings were interpreted to suggest a specific deficiency at the level of phonological monitoring, rather than a general monitoring, reaction time or auditory monitoring deficit in PWS. Educational objectives: As a result of this activity, the participant should: (1) identify and assess the literature on phonological encoding skills in PWS, (2) enumerate and evaluate some major psycholinguistic theories of stuttering, and (3) describe the mechanism by which defective phonological encoding can disrupt fluent speech production.     

Does neuroscience hold promise for the further development of behavior therapy? The case of emotional change after exposure in anxiety and depression

Over the last few years, the integration of biological and psychological models has become increasingly important in clinical psychology. This paper presents a neurobiological framework for exploring how neuroscience research may be valuable in the context of new developments in behavior therapy. The importance of the cortical-subcortical circuitry of emotion processing for investigating the working mechanisms of exposure therapy is illustrated by current neuroimaging research. The implication is that during exposure therapy the focus of attention must be fully directed towards the emotional content of the threatening situation to facilitate prefrontal control over the amygdala and that new contextual information, of emotional salience, must be added to create inhibitory projections from the hippocampus. In addition, some possible mechanisms of action for different therapeutic approaches to both anxiety and depression and the role of neuroimaging techniques in predicting treatment outcome are discussed.     

Confirmatory factor analyses of DSM-IV Cluster C personality disorder criteria

Notwithstanding its research and clinical relevance, the dimensionality and validity of the DSM-IV avoidant, dependent, and obsessive-compulsive personality disorders (PDs) criteria is still a largely unexplored topic. The aim of this study was to test the factor structure for DSM-IV Cluster C PD criteria in a sample of 641 consecutively admitted outpatients. Factor analysis results suggested that avoidant, dependent, and obsessive-compulsive PDs share a common latent dimension, and supported the three-factor structure of both observer and self-report ratings of DSM-IV Cluster C PD criteria. The pattern of factor loadings, however, was different from the one expected according to the DSM-IV classification.     

Self-benefiting in the allocation of scarce resources: leader-follower effects and the moderating effect of social value orientations

Previous research on the allocation of scarce resources suggests that people who are assigned to higher positions (e.g., leaders) are more likely to make self-benefiting allocations than people who are assigned to lower positions (e.g., followers). In this article, the authors investigated the proposition that these findings would be moderated by people's social value orientations. In two experimental studies, the authors assigned participants either to the role of leader or follower and assessed the participants' social value orientations. In agreement with predictions, the findings show that position effects are moderated by social value orientation. Social value orientations only affected the allocation behavior of the leaders: Proself leaders allocated more resources to themselves than did prosocial leaders. Additional analyses indicate that these effects are mediated by feelings of entitlement.     

Testing antecedents to sales performance in postapartheid era: a field study

The predictors of objectively measured sales performance were assessed with 245 sales representatives from a large South African life insurance company. Sales representatives completed measures of their locus of control, entrepreneurial attitudes, biographical history, and performance was assessed from company records of sales, net commissions earned, and lapse ratios. The nature of employment contract, job status, and race explained significant differences in performance outcomes. The predictive nature of locus of control and entrepreneurial attitudes for performance outcomes was tested using structural equation modeling procedures, with limited validity. The implications for research and practice are also discussed.     

Automaticity: a theoretical and conceptual analysis

Several theoretical views of automaticity are discussed. Most of these suggest that automaticity should be diagnosed by looking at the presence of features such as unintentional, uncontrolled/uncontrollable, goal independent, autonomous, purely stimulus driven, unconscious, efficient, and fast. Contemporary views further suggest that these features should be investigated separately. The authors examine whether features of automaticity can be disentangled on a conceptual level, because only then is the separate investigation of them worth the effort. They conclude that the conceptual analysis of features is to a large extent feasible. Not all researchers agree with this position, however. The authors show that assumptions of overlap among features are determined by the other researchers' views of automaticity and by the models they endorse for information processing in general.     

Reasoning rats: forward blocking in Pavlovian animal conditioning is sensitive to constraints of causal inference

Forward blocking is one of the best-documented phenomena in Pavlovian animal conditioning. According to contemporary associative learning theories, forward blocking arises directly from the hardwired basic learning rules that govern the acquisition or expression of associations. Contrary to this view, here the authors demonstrate that blocking in rats is flexible and sensitive to constraints of causal inference, such as violation of additivity and ceiling considerations. This suggests that complex cognitive processes akin to causal inferential reasoning are involved in a well-established Pavlovian animal conditioning phenomenon commonly attributed to the operation of basic associative processes.     

When are neighbours hostile? Inhibitory neighbour effects in visual word recognition

Using masked priming, Segui and Grainger (1990) reported inhibitory effects of higher frequency neighbours on lower frequency targets (e.g., avec - AVEU), but not of lower frequency neighbours on higher frequency targets (e.g., aveu - AVEC). Conversely, with unmasked (conscious) priming, they observed inhibition for word pairs of the type "aveu - AVEC", but not for word pairs of the type "avec - AVEU". Both inhibitory effects were explained in terms of the frequency difference between the prime and the target. We argue that the observed inhibitory effects may emerge from the absolute frequency of the prime or the target, rather than their relative frequency. To test this, we investigated inhibitory effects between neighbour words of the same frequency under both masked and unmasked priming conditions. The results showed inhibition for same-frequency neighbours in case the prime and the target were high-frequency words, but not in case the prime and the target were low-frequency words. The theoretical implications of the findings are discussed within the context of interactive activation based models (e.g., Grainger & Jacobs, 1996; McClelland & Rumelhart, 1981).