A comparison of Guided Imaginal Coping and imaginal exposure in the treatment of panic disorder

The present study evaluated the efficacy of a new intervention, Guided Imaginal Coping (GIC), compared to imaginal exposure (IEX), and a waiting-list control (WLC) condition among 24 clinic outpatients meeting DSM-III-R criteria for panic disorder (PD) or PD with agoraphobia. GIC was the more consistently effective intervention, with individuals demonstrating significant improvement in frequency and severity of panic attacks (Pas) as well as significant reductions in physiological and subjective arousal to provocative imagery. Individuals in the IEX intervention demonstrated less consistent improvement on the dependent measures, while individuals in the WLC condition essentially remained unchanged. Both GIC and IEX were effective according to a composite measure of clinically significant improvement. However, only GIC was superior to the WLC condition when clinical improvement was defined as zero PAs at follow-up. These findings, while preliminary, suggest that GIC can be added to the armamentarium of effective approaches to treating PD.     

Local knowledge and comparative scientific traditions

This article argues that all knowledge is inherently local and that localness provides the basis for comparison between indigenous scientific traditions or knowledge production systems. As collective bodies of knowledge, many of the significant differences between knowledge production systems lie in the work involved in creating assemblages from differing practices. Much of the work can be seen in the social strategies and technical devices employed in creating equivalences and connections whereby otherwise heterogeneous and isolated knowledges are enabled to move in space and time from the local site and moment of their production and application to other places and times. In this way contemporary technosciences are compared with the knowledge systems of the medieval mastermasons, the Anasazi, the Inca, the Australian Aborigines and the Pacific navigators.     

Family preservation using multisystemic treatment: Long-term follow-up to a clinical trial with serious juvenile offenders

In a randomized clinical trial, multisystemic family preservation was shown to significantly reduce rates of criminal activity and incarceration in a sample of 84 serious juvenile offenders and their multi-need families. In the current study, archival records were searched for re-arrest an average of 2.4 years post-referral. Survival analysis showed that youths who received multisystemic family preservation were less likely to be re-arrested than were youths who had received usual services. Such results represent the first controlled demonstration that family preservation, when delivered via a clearly specified treatment model, has lasting effects with serious juvenile offenders. Implications for family preservation and juvenile justice research are discussed.     

Clarifying the task

Those who would enquire into therelationship between “health conceptions” and “health care consequences” are faced with a formidable task. In order to make this challenge manageable it is necessary to define the scope of the task as precisely as possible. Are we, for instance, faced with a purely theoretical challenge; a task for applied philosophy, or must we employ multi-disciplinary methods? This paper argues that while philosophy has a central clarifying role, inquiry into the relationship between “health conceptions” and “health care organisation” can be done properly only through the combined efforts of several disciplines. Unless we are to be concerned only with abstract models it is essential to take account of the reality of health care situations. Given this it is suggested that the study of “health conceptions” is only a part of a greater task (unless all conceptions are to count as “health conceptions”). What is needed is understanding of the possible and actual purposes of health care, and detailed study of their practical implications.     

Praxis makes perfect: Illness as a bridge between biological concepts of disease and social conceptions of health

Analyses of biological concepts of disease and social conceptions of health indicate that they are structurally interdependent. This in turn suggests the need for a bridge theory of illness. The main features of such a theory are an emphasis on the logical properties of value terms, close attention to the features of the experience of illness, and an analysis of this experience as action failure, drawing directly on the internal structure of action. The practical applications of this theory are outlined for a number of problems in each of the three main practical areas, clinical work, teaching and research. In each case the resources of the theory suggest new models and generate new results. The full practical significance of the theory, however, is shown to consist in the way in which it ties together biological and social theories into an integrated picture of the conceptual structure of medicine as a whole. It is argued, finally, that practical efficiency of this kind is a test of theory not only in the philosophy of medicine but also in general philosophy.     

Calibration of a color monitor for visual psychophysics

It has become common for stimuli used in visual psychophysical experiments to be presented on high-resolution color cathode-ray tubes (CRTs) such as the Barco CDCT 6551. These enable a flexibility of color, spatial-frequency content, temporal-frequency content, duration, size, and position that is not provided by most other media. CRTs are, however, not perfect; they suffer from the effects of temporal instability, spatial variability, lack of phosphor constancy, gun interdependence, and gun nonlinearity. This paper describes methods of assessing these aspects of monitor performance with respect to how significant each may be in psychometric terms. Although every application of CRT use in visual psychophysics is different, some general rules can be formulated to help ensure that unwanted effects are kept to a minimum. For the CRT used in this study (Barco CDCT 6551), a warm-up time of 30-45 min is necessary before chromatic and luminous stability ensues. Restriction of individual gun outputs to within 10%-90% of the possible range ensures that the effects of gun interdependence and lack of phosphor constancy are negligible. Calibration methods dealing with the linearization of gun output are also discussed.     

比较研究-影响中美儿童计算能力差异的认知因素

本研究要确定中美儿童基本计算技能的差异是否与他们使用的解题策略和基本加工过程的速度有关。为此,对中美两国的一年级儿童进行了书面计算能力测验,以及一组计算机呈现的加法作业。中国儿童在计算能力测验上表现出3:1的操作优势。中美儿童使用的解题策略种类一样,但是,中国儿童在策略综合运用的发展程度上超过美国儿童,检索策略的加工速度也超过美国儿童。显然,策略运用和加工速度的差异促成了中国儿童在计算能力测验上的优势.     

Potentiation of the pressor response to stress by tolbutamide in dogs

Tolbutamide has previously been shown to amplify the pressor effects of “exogenous” catecholamines in conscious dogs, possibly due to sensitization of the α₁-adrenoreceptor-mediated vasoconstriction. The objective of this study was to examine if tolbutamide also amplifies the pressor effects of “endogenous” catecholamines released during psychological stress (classical Pavlovian aversive conditioning). Experiments were conducted in β-adrenoreceptor-blocked (propranolol, 1 mg/kg, i.v.) conscious dogs (n=4) trained in classical aversive conditioning. Conditioning was accomplished by following a tone (CS+) with a 1/2 second shock; another tone (CS-) was not followed by any shock and served as control. With saline pretreatment, aversive conditioning (i.e., CS+) increased mean arterial pressure (MAP) only by approximately 4.7% when compared to CS-, whereas with tolbutamide (45 mg/kg, i.v.) pretreatment, the increase in MAP induced by CS+ beyond what was induced by the CS- (approximately 6.2%) was significantly (p<0.05) larger than that with saline pretreatment. In isolated canine femoral arterial segments (n=4), the vasoconstrictor effect of phenylephrine (an α₁-agonist) at 5×10^?6M (which was the EC₅₀ value) was amplified by 2×10^?2M of tolbutamide from 54.0±2.0% to 66.9±2.1%. In conclusion, tolbutamide amplifies the pressor effects of “endogenous” catecholamines in conscious dogs, possibly by sensitization of the α₁-adrenoreceptor-mediated vasoconstriction. This mechanism of action is novel and has not been reported with other agents.     

Distractor clustering enhances detection speed and accuracy during selective listening

The effects of distractor clustering on target detection were examined in two experiments in which subjects attended to binaural tone bursts of one frequency while ignoring distracting tones of two competing frequencies. The subjects pressed a button in response to occasional target tones of longer duration (Experiment 1) or increased loudness (Experiment 2). In evenly spaced conditions, attended and distractor frequencies differed by 6 and 12 semitones, respectively (e.g., 2096-Hz targets vs. 1482- and 1048-Hz distractors). In clustered conditions, distractor frequencies were grouped; attended tones differed from the distractors by 6 and 7 semitones, respectively (e.g., 2096-Hz targets vs. 1482- and 1400-Hz distractors). The tones were presented in randomized sequences at fixed or random stimulus onset asynchronies (SOAs). In both experiments, clustering of the unattended frequencies improved the detectability of targets and speeded target reaction times, Similar effects were found at fixed and variable SO As. Results from the analysis of stimulus sequence suggest that clustering improved performance primarily by reducing the interference caused by distractors that immediately preceded the target.     

Linguistic Phenomena and Language Selection in the REM Dreams of German-English Bilinguals

Sixteen German-English bilinguals were studied in a sleep laboratory for four nonconsecutive nights each. Half were native English speakers living in Zürich, and half native German speakers living in Atlanta. Presleep thought samples were solicited each evening and REM dream reports each night; subjects judged the waking appropriateness of their imagined speech and language phenomena, and also identified waking sources of their dream imagery, the following mornings. Incidences of dreaming and of speech therein generally were similar to those of monolinguals. Whether sessions were conducted in German (two nights) or English (two nights) did directly influence language selection in subjects' dreams. Judged appropriateness of language selection to imagined events was very high for thought samples, and high for REM dreams. Sources for thought samples were generally consonant with the language dominant at study site; for REM dreams this relationship was considerably weaker. Judged waking appropriateness to imagined situations was more strongly related to language selection than was the language reference of the supposed sources of those situations.