Effects of anorectic drugs on food intake under progressive-ratio and free-access conditions in rats

The effects of two anorectic drugs, dexfenfluramine and phentermine, on food intake under different food-access conditions were examined. Experiment 1 compared the effects of these drugs on food intake under a progressive-ratio (PR) schedule and free-access conditions. Dexfenfluramine decreased food intake under both conditions, but the doses required to decrease intake under free-access conditions were higher than those required to reduce intake under the PR condition. Intermediate doses of phentermine sometimes increased breaking points, and higher doses decreased them. Phentermine decreased food intake at the same doses under both access conditions. Thus the potency of dexfenfluramine, but not phentermine, to decrease food-maintained behavior depended upon the food-access condition. Experiment 2 used a novel mixed progressive-ratio schedule of food delivery to study the duration of drug effects. Sessions consisted of five components separated by 3-hr timeouts. The ratio requirement reset at the beginning of each component and a new breaking point was obtained. Both dexfenfluramine and phentermine dose-dependently decreased breaking points early in the session. In some rats, compensatory increases in breaking point were observed. That is, breaking points later in the session increased over control levels, resulting in no change in the total number of food pellets earned for the session compared to control. The present findings suggest that the effects of some anorectic drugs depend upon the access conditions for food; increasing the effort to obtain food may enhance their ability to decrease food-maintained behavior.     

Task characteristics and performance in interpersonal cognitive problem solving

The authors examined the extent to which performance on interpersonal cognitive problem-solving (ICPS) tasks is affected by whether the goals within the dilemmas to be addressed are sex typed. Fifty children, aged 7-8 years old, were tested for the core ICPS skills of Alternative Solutions Thinking (AST) and Consequential Thinking (CT) on a series of 8 social problem-solving tasks, 4 having goals characteristically more attractive to boys and 4 with goals more attractive to girls. A 2 x 2 MANOVA was used to compare the performances of boys and girls on each set of sex-typed tasks with the 3 dependent variables of liking for the tasks, number of alternative solutions suggested, and the number of consequences anticipated. As expected, liking for the tasks was higher if the activities were characteristically associated with the participant's own gender (p < .001), although the different tasks did not produce any significant gender differences in the numbers of AST or CT suggestions they prompted. Gender differences in children's peer relationships were considered, and the implications of these results for the format of ICPS interventions are noted.     

Disrupting feedback processing interferes with rule-based but not information-integration category learning

The effect of a sequentially presented memory scanning task on rule-based and information-integration category learning was investigated. On each trial in the short feedback-processing time condition, memory scanning immediately followed categorization. On each trial in the long feedback-processing time condition, categorization was followed by a 2.5-sec delay and then memory scanning. In the control condition, no memory scanning was required. Rule-based category learning was significantly worse in the short feedback-processing time condition than in the long feedback-processing time condition or control condition, whereas information-integration category learning was equivalent across conditions. In the rule-based condition, a smaller proportion of observers learned the task in the short feedback-processing time condition, and those who learned took longer to reach the performance criterion than did those in the long feedback-processing time or control condition. No differences were observed in the information integration task. These results provide support for a multiple-systems approach to category learning and argue against the validity of single-system approaches.     

Update Semantics of Security Protocols

We present a model-theoretic approach for reasoning about security protocols, applying recent insights from dynamic epistemic logics. This enables us to describe exactly the subsequent epistemic states of the agents participating in the protocol, using Kripke models and transitions between these based on updates of the agents’ beliefs associated with steps in the protocol. As a case study we will consider the SRA Three Pass protocol and discuss the Wide-Mouthed Frog protocol.     

Emotional intensity predicts autobiographical memory experience

College students generated autobiographical memories from distinct emotional categories that varied in valence (positive vs. negative) and intensity (high vs. low). They then rated various perceptual, cognitive, and emotional properties for each memory. The distribution of these emotional memories favored a vector model over a circumplex model. For memories of all specific emotions, intensity accounted for significantly more variance in autobiographical memory characteristics than did valence or age of the memory. In two additional experiments, we examined multiple memories of emotions of high intensity and positive or negative valence and of positive valence and high or low intensity. Intensity was a more consistent predictor of autobiographical memory properties than was valence or the age of the memory in these experiments as well. The general effects of emotion on autobiographical memory properties are due primarily to intensity differences in emotional experience, not to benefits or detriments associated with a specific valence.     

Attempting to avoid false memories in the Deese/Roediger—McDermott paradigm: Assessing the combined influence of practice and warnings in young and old adults

On each of five study-test trials, young and old adults attempted to memorize the same list of 60 words (e.g., bed, rest, awake), which were blocked according to their convergence on four corresponding associates. Half of the participants in each age group were given an explicit warning about the DRM paradigm prior to encoding and were asked to attempt to avoid recalling any associated but nonpresented words (e.g., sleep). Lists were presented auditorily at either a fast (1,250 msec/word) or a slow (2,500 msec/word) rate. Without a warning, the probability of veridical recall across trials increased for both age groups; however, the probability of false recall across trials decreased only for young adults. When a warning about false recall was provided, young adults virtually eliminated false recall by the second trial. Even though old adults also used warnings to reduce false recall on Trial 1, they were still unable to decrease false memories across the remaining four study-test trials. Old adults also reduced false recall more with slow than with fast presentation rates. Taken together, these findings suggest that old adults have a breakdown in spontaneous, self-initiated source monitoring as reflected by little change in false recall across study-test trials but a preserved ability to use experimenter-provided warnings or slow presentation rates to reduce false memories.     

Naturalizing the Human or Humanizing Nature: Science, Nature and the Supernatural

The present paper challenges the narrow scientistic conception of Nature that underlies current projects of naturalization involving, say, evaluative or intentional discourse. It is more plausible to hold that science provides only a partial characterization of the natural world. I consider McDowell's articulation of a more liberal naturalism, one which recognizes autonomous normative facts about reasons, meanings and values, as genuine constituents of Nature on a more liberal conception of it. Several critics have claimed that this account is vitiated by the threat of supernaturalism. Responsiveness to normative facts is, I argue, a phenomenological datum that we have good reason to take at face value. I trace the source of the supernaturalist objection to a misreading of McDowell's perceptual analogy with respect to value and a related failing to clearly distinguish physical and logical notions of an object.     

From Aristotle's Syllogistic to Stoic Conditionals: Holzwege or Detectable Paths?

This paper is chiefly aimed at individuating some deep, but as yet almost unnoticed, similarities between Aristotle's syllogistic and the Stoic doctrine of conditionals, notably between Aristotle's metasyllogistic equimodality condition (as stated at APr. I 24, 41b27–31) and truth-conditions for third type (Chrysippean) conditionals (as they can be inferred from, say, S.E. P. II 111 and 189). In fact, as is shown in §1, Aristotle's condition amounts to introducing in his (propositional) metasyllogistic a non-truthfunctional implicational arrow '', the truth-conditions of which turn out to be logically equivalent to truth-conditions of third type conditionals, according to which only the impossible (and not the possible) follows from the impossible. Moreover, Aristotle is given precisely this non-Scotian conditional logic in two so far overlooked passages of (Latin and Hebraic translations of) Themistius' Paraphrasis of De Caelo (CAG V 4, 71.8–13 and 47.8–10 Landauer). Some further consequences of Aristotle's equimodality condition on his logic, and notably on his syllogistic (no matter whether modal or not), are pointed out and discussed at length. A (possibly Chrysippean) extension of Aristotle's condition is also discussed, along with a full characterization of truth-conditions of fourth type conditionals.     

The effect of the September 11 terrorist attacks on suicide and deliberate self-harm: a time trend study

Suicide rates may be affected by world news. Our objective was to investigate the possible impact of the terrorist attacks of September 11, 2001, on suicidal behavior in the Netherlands. There was evidence of an increase in rates of suicide and deliberate self-harm in the weeks immediately following the attacks. These findings contrast with Durkheim's (1897) original suggestion that suicide rates decline in times of war and outside threat but are in line with findings of increases in suicidal behavior after media coverage of lethal violence.