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131.
Sprague-Dawley rats drank sweetened (3% dextrose + 0.144% saccharin, w/v) or unflavored water for 18 days and subsequent pain reactivity was assessed using a hot plate. Compared to the rats that consumed unflavored water, the rats that consumed sweet water responded more quickly on the hot plate indicating that their threshold for pain was lowered. Another group of rats given identical exposure to the fluids had their brains prepared for measuring opiate receptor binding using the delta-receptor ligand [3H]D-Ala-D-Leu-enkephalin ([3H]DADLE) and the mu-receptor selective ligand [3H]Tyr-D-Ala-Gly-MePhe-Gly-ol ([ 3H]DAGO). Binding of these opiates to mu- and delta-receptors in the cerebral cortex, striatum, hippocampus, hypothalamus, brain stem, and remaining brain regions was the same for the rats that drank sweet fluids and those that drank unflavored water. These findings suggest that drinking sweet fluids lowers pain thresholds but does not alter mu- and delta-receptors.  相似文献   
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Attitudes toward older and younger adults: a meta-analysis   总被引:3,自引:0,他引:3  
Attitudes toward the elderly have been examined in a number of empirical studies, yet the question of whether the elderly are viewed more negatively than younger persons has not been resolved. A meta-analysis of the literature was conducted to examine this question; results demonstrated that attitudes toward the elderly are more negative than attitudes toward younger people. However, smaller differences between the evaluations of elderly and younger targets were found when (a) the study used measures of personality traits (compared with measures of competence), (b) there were a larger number of dependent measures included in the effect size, (c) specific information was provided about the target person (compared with when a general target such as old person was used), and (d) a between-subjects design (compared with a within-subjects design) was used. These results support Lutsky's (1981) conclusion that age, in and of itself, seems to be less important in determining attitudes toward the elderly than other types of information. The methodological limitations within the literature and a need to consider multiple components of attitudes toward older individuals are discussed.  相似文献   
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We investigated longitudinally the effects of a stroke on the social support systems and well-being of the patient's primary support person, both acutely and as the condition stabilized. Individuals who had suffered a first stroke and a primary support person participated in two waves of data collection, carried out in 6-month intervals beginning 7 weeks after the stroke. Our data show that the prevalence of depressive symptoms is from 2 1/2 to 3 1/2 times higher than rates found among representative samples of middle-aged and elderly populations. Mean level of depression did not change over time, although level of optimism declined significantly. Multiple regression analyses showed that levels of depression and perceived burden in support persons are highly related to aspects of the stroke such as its severity, and that demographic variables such as age and income play a relatively minor role in attenuating these relations in the acute adjustment phase. However, from 7 to 9 months after the stroke, well-established demographic variables such as health, income, and age were significant predictors of depression. Individuals who were older and who had good health and higher incomes were least depressed.  相似文献   
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Past research on delinquency and crime has provided convincing data about correlates but not about causes, because it has been largely cross-sectional in design. Whereas cross-sectional research focuses on variations between subjects, longitudinal research can provide information about changes within subjects, which are more important for causes, prevention, and treatment. Many of the most important results in criminology have been obtained in longitudinal or experimental studies, and the major studies of these types are reviewed here. It is now desirable to combine the two methods in a new coordinated program of longitudinal studies including experimental interventions or quasi-experimental analyses. Such projects could study several overlapping cohorts, extend from birth to adulthood, have frequent data collection, and obtain data from a variety of sources about many different types of antisocial behavior.  相似文献   
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A software package called PAST (Programmer Assessment Software Tools) is described. PAST was designed as a research and diagnostic tool to analyze how programmers develop and test program code. PAST uses line changes between successive compiles to estimate a programmer’s cognitive processing. Line changes are highlighted and graphically presented between any two versions or compiles. Summary graphs and statistics across all versions also are provided. Applications of PAST for expanding our understanding of programming and applying it to research, teaching, and learning are discussed.  相似文献   
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High-resolution CRT displays are subject togeometric distortion: lines that are straight in the internal coordinates of the graphics software and hardware are curved when projected onto a plane in the observer’s line of sight. As the available resolution of CRT screens increases, it becomes more difficult to measure and correct for this distortion. We present a simple, highly accurate method for determining the mapping between internal coordinates and the viewing plane. It requires that an observer, using a calibration program, adjust triples of displayed points until they are collinear. A metal straightedge placed between the observer and the screen aids in this judgment. We describe the calibration of an IBM Enhanced Graphics Display in high-resolution mode (350 × 640 pixels), and illustrate how to use the estimated mapping to choose internal coordinates to draw undistorted figures that are accurate to within 0.5 pixel. The method can be used to assess or to correct the accuracy of visual displays. The method is relevant to experiments in spatial vision, spatial perception, perception of dot patterns, and any application in which geometrically accurate stimuli are required.  相似文献   
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After outlining the predominant approaches which currently inform student counselling a case is made for adopting a developmental systemic paradigm, locating individual difficulties within the context of a family dilemma. The view is taken that family systems thinking and individual approaches can be complementary and that systemic work need not be restricted to formal family therapy and the technology this implies.  相似文献   
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