Assessment of applied research and development: Diversification for science policy

In this paper a method is outlined for measuring the diversity of the results of applied R&D with the use of IPC (International Patent Classification). The method has been tested in the contexts of the academic physical, engineering, and chemical institutes. The trend of applied research at a given institute increases both at the level of classes and subclasses, and at the IPC level. Inventions developed within specializations at each institute have a greater efficiency than other forms of inventive activity. The objective was to seek the optimal extent of diversification of applied R&D, which would simultaneously ensure the preservation of the scientific specialization of an institute, the high level of scientific research associated with developing innovations, and the high overall efficiency of each institute.     

Local knowledge and comparative scientific traditions

This article argues that all knowledge is inherently local and that localness provides the basis for comparison between indigenous scientific traditions or knowledge production systems. As collective bodies of knowledge, many of the significant differences between knowledge production systems lie in the work involved in creating assemblages from differing practices. Much of the work can be seen in the social strategies and technical devices employed in creating equivalences and connections whereby otherwise heterogeneous and isolated knowledges are enabled to move in space and time from the local site and moment of their production and application to other places and times. In this way contemporary technosciences are compared with the knowledge systems of the medieval mastermasons, the Anasazi, the Inca, the Australian Aborigines and the Pacific navigators.     

Toward a new conceptualization and operationalization of risk perception within the genetic counseling domain

The purpose of this paper is twofold. First, it provides an historical overview of studies of risk, risk perception, and decision making under risk within the genetic counseling domain. Second, it proposes an alternative conceptualization and operationalization for the study of risk perception. The conceptualization involves probability, adversity, incompleteness, and ambiguity. Prior studies of risk perception focus on the recurrence risk and operationalize risk perception by asking for interpretations of the magnitude of the probability of the outcome. Their focus is on the probability of a particular outcome. We formulate the problem in terms of a gamble and suggest that risk perception be operationalized in terms of the riskiness of the gamble. Our focus is on the riskiness of a decision option which entails two or more outcomes.     

The crane's foot: The rise of the pedigree in human genetics

The standard pedigree used by geneticists is intimately connected to the history of genetics. Pedigrees drawn today are based on standards established in the early decades of the twentieth century. Those standards were established by geneticists who pursued an active interest in eugenics. The slightly different standards followed in America vs. England to some extent followed the stronger support of Mendelism by the Americans, as well as the individual preferences of the leading human geneticists in those countries.     

Development of knowledge bases and the reliability of a decision support system for behavioral treatment consultation for persons with mental retardation: The Mental Retardation-Expert

The development of expert and decision support systems requires the collection, organization, codification, and storage of a body of specialized knowledge. The development, using reconstructive methods, of two such knowledge bases, the first containing the current scientific literature and the second containing an expert’s knowledge, is described for an automated decision support system, the Mental Retardation-Expert. This system provides practitioners with assistance in the treatment of aggressive, self-injurious, and destructive behaviors displayed by individuals with mental retardation or developmental disabilities. The average interobserver reliability of the expert knowledge base ranged from 92.5% to 95.0% when calculated across four clinicians’ assessments of 31 abstracted cases.     

Clarifying the task

Those who would enquire into therelationship between “health conceptions” and “health care consequences” are faced with a formidable task. In order to make this challenge manageable it is necessary to define the scope of the task as precisely as possible. Are we, for instance, faced with a purely theoretical challenge; a task for applied philosophy, or must we employ multi-disciplinary methods? This paper argues that while philosophy has a central clarifying role, inquiry into the relationship between “health conceptions” and “health care organisation” can be done properly only through the combined efforts of several disciplines. Unless we are to be concerned only with abstract models it is essential to take account of the reality of health care situations. Given this it is suggested that the study of “health conceptions” is only a part of a greater task (unless all conceptions are to count as “health conceptions”). What is needed is understanding of the possible and actual purposes of health care, and detailed study of their practical implications.     

Calibration of a color monitor for visual psychophysics

It has become common for stimuli used in visual psychophysical experiments to be presented on high-resolution color cathode-ray tubes (CRTs) such as the Barco CDCT 6551. These enable a flexibility of color, spatial-frequency content, temporal-frequency content, duration, size, and position that is not provided by most other media. CRTs are, however, not perfect; they suffer from the effects of temporal instability, spatial variability, lack of phosphor constancy, gun interdependence, and gun nonlinearity. This paper describes methods of assessing these aspects of monitor performance with respect to how significant each may be in psychometric terms. Although every application of CRT use in visual psychophysics is different, some general rules can be formulated to help ensure that unwanted effects are kept to a minimum. For the CRT used in this study (Barco CDCT 6551), a warm-up time of 30-45 min is necessary before chromatic and luminous stability ensues. Restriction of individual gun outputs to within 10%-90% of the possible range ensures that the effects of gun interdependence and lack of phosphor constancy are negligible. Calibration methods dealing with the linearization of gun output are also discussed.