The relationship of borderline personality disorder, life events and functioning in an Australian psychiatric sample

Studies have documented poor functioning and higher rates of negative life events in association with personality disorders (PDs), in particular with borderline personality disorder (BPD). The current study investigated the impact of recent life events, daily hassles and uplifts on psychosocial functioning in patients with PDs, while extending previous research by examining the role of perceived coping effectiveness and perceived stress of recent life events. Ninety-seven participants (Axis I group, N = 30; BPD group, N = 23; Other PD group, N = 44) completed measures of functioning, recent life events, daily hassles and uplifts. Results indicated that the BPD group reported the poorest levels of functioning, especially interpersonal functioning. The BPD group also reported more negative life events, particularly in the interpersonal relationships, personal health, crime, and financial domains. The BPD group experienced less uplifts, more hassles and found employment circumstances particularly stressful and difficult to cope with. Intensity of hassles was a predictor of functioning independent of a BPD diagnosis. A greater frequency of life events was closely associated with a non-BPD diagnosis in predicting a decrease in psychosocial functioning.     

Antidepressants and cognitive-behavioral therapy for symptom syndromes

Somatic symptoms are common in primary care and clinicians often prescribe antidepressants as adjunctive therapy. There are many possible reasons why this may work, including treating comorbid depression or anxiety, inhibition of ascending pain pathways, inhibition of prefrontal cortical areas that are responsible for "attention" to noxious stimuli, and the direct effects of the medications on the syndrome. There are good theoretical reasons why antidepressants with balanced norepinephrine and serotonin effects may be more effective than those that act predominantly on one pathway, though head-to-head comparisons are lacking. For the 11 painful syndromes review in this article, cognitive-behavioral therapy is most consistently demonstrated to be effective, with various antidepressants having more or less randomized controlled data supporting or refuting effectiveness. This article reviews the randomized controlled trial data for the use of antidepressant and cognitive-behavior therapy for 11 somatic syndromes: irritable bowel syndrome, chronic back pain, headache, fibromyalgia, chronic fatigue syndrome, tinnitus, menopausal symptoms, chronic facial pain, noncardiac chest pain, interstitial cystitis, and chronic pelvic pain. For some syndromes, the data for or against treatment effectiveness is relatively robust, for many, however, the data, one way or the other is scanty.     

Summation in causal learning: elemental processing or configural generalization?

Results from human causal learning tasks that employ multiple cues are often interpreted in terms of the elemental theory of Rescorla and Wagner (1972). However, most results can also be successfully interpreted by the configural model proposed by Pearce (1987, 1994). One method of discriminating between these alternatives is through an investigation of summation and overexpectation. Indeed, demonstrations of these phenomena are fundamental to an elemental approach but are generally incompatible with an account that involves configural processing. Using a procedure in which the magnitude of the outcome varied, evidence for both summation and overexpectation was obtained in two experiments.     

Hangover frequency and risk for alcohol use disorders: evidence from a longitudinal high-risk study

Data from a prospective high-risk study (N=489; 51% with a family history of alcoholism) were used to test whether family history is associated with greater hangover proneness and whether hangover is a risk factor for alcohol use disorders. Hangover was more frequent in family-history-positive participants during the college years. Persons with an alcohol diagnosis showed excess hangover before earning a diagnosis. Year 1 hangover predicted alcohol use disorders at Years 7 and 11, even when family history, sex, Year 1 diagnoses, and Year 1 drinking were statistically controlled. Several nonhangover drinking symptoms failed to predict later diagnoses. Taken together, the findings suggest a need for further research and theory on the role of hangover in the etiology of drinking problems.     

Co-ordination of bimanual movements in a centrally deafferented patient executing open loop reach-to-grasp movements

Many everyday tasks require that we use our hands co-operatively. For tasks where both hands are required to perform the same action, a common motor program can be used. But, where each hand must perform a different action, some degree of independent control of each hand is required. In this paper we examine the co-ordination of bimanual movement kinematics in a female patient recovering from brain injury involving anterior regions of the parietal lobe of the right hemisphere, which has resulted in a dense hemianaesthesia of her left arm. A particular focus of this paper is the co-ordination of bimanual movements for reaches executed without visual feedback. Specifically we present new data, which quantify the synchronisation of patient D.B.'s hands by comparing their relative time lag at the start and the end of her bimanual reaches. The results are discussed with particular reference to the role played by limb proprioception in the planning and control of prehension movements.     

Interpopulation variation in the risk-related decisions of <Emphasis Type="Italic">Portia labiata</Emphasis>, an araneophagic jumping spider (Araneae,Salticidae), during predatory sequences with spitting spiders

The extent to which decision-making processes are constrained in animals with small brains is poorly understood. Arthropods have brains much smaller and simpler than those of birds and mammals. This raises questions concerning limitations on how intricate the decision-making processes might be in arthropods. At Los Ba?os in the Philippines, Scytodes pallidus is a spitting spider that specialises in preying on jumping spiders, and Portia labiata is a jumping spider that preys on S. pallidus. Scytodid spit comes from the mouth, and egg-carrying females are less dangerous than eggless scytodids because the female uses her chelicerae to hold her eggs. Held eggs block her mouth, and she has to release them before she can spit. The Los Ba?os P. labiata sometimes adjusts its tactics depending on whether the scytodid encountered is carrying eggs or not. When pursuing eggless scytodids, the Los Ba?os P. labiata usually takes detour routes that enable it to close in from behind (away from the scytodid's line of fire). However, when pursuing egg-carrying scytodids, the Los Ba?os P. labiata sometimes takes faster direct routes to reach these safer prey. The Los Ba?os P. labiata apparently makes risk-related adjustments specific to whether scytodids are carrying eggs, but P. labiata from Sagada in the Philippines (allopatric to Scytodes) fails to make comparable risk-related adjustments.