Hippocampal damage and amnesia following hypoxia and ischemia are described in the few published adult cases of suicide attempt by hanging. However, a recent review (Caine &; Watson, 2000Caine, D. and Watson, J. D.2000. Neuropsychological and neuropathological sequelae of cerebral anoxia: A critical review. Journal of the International Neuropsychology Society, 6: 86–99. [CROSSREF][Crossref], [PubMed], [Web of Science ®], [Google Scholar]) suggests a variable pattern of brain involvement and neuropsychological impairments following hypoxic-ischemic injury that may or may not involve amnesia. To help clarify the impact of hanging on the developing brain, we examined neuropsychological functioning in two adolescents who survived suicide attempt by hanging. Despite differences in Glasgow Coma Scale (GCS), coma duration, and structural imaging findings, both patients had similar IQ (VIQ > PIQ) and presented with various combinations of deficits in expressive/receptive language, visual-constructional and perceptual ability, processing speed, attention, working memory, and/or executive functioning shortly after injury. In spite of their similarities, only one of the patients presented with classic amnesia symptoms in his early recovery. This patient was evaluated 1 year postinjury, and persistent deficits in processing speed and memory encoding were noted. Several hanging-related variables, including longer estimated hanging duration, greater weight, and severe airway edema, were thought to place this patient at increased risk for cognitive deficits. Clinical MRI scans of this patient obtained 6 weeks postinjury revealed mild volume loss as well as abnormalities in bilateral superior cortex. However, CT and MRI scans obtained throughout early recovery did not reveal overt evidence of injury to specific memory-related structures. Comprehensive neuropsychological evaluation of all adolescent survivors of suicide attempt by hanging is recommended, as a variety of postacute cognitive deficits were observed in these patients despite relatively short (≤ 15 minutes) estimated hanging durations. 相似文献
Abstract As a result of the passage of Public Law 96-272, home-based family services have proliferated throughout the United States, with family therapy playing a vital role. Voices of therapists providing these services have been absent from literature. Ten therapists participated in this study; each had experience providing home-based and clinic-based family therapy. A qualitative strategy was used to explore therapists' perspectives on factors regarding home-based family preservation services. Four themes emerged from semistructured interviews: the home environment, safety, context preference, and efficiency and effectiveness. Three recommendations are drawn from results and discussed. 相似文献
This longitudinal study investigated whether age is associated with increased dispersion among major domains of cognitive ability. Three samples were examined: the full sample of 760 elderly community dwellers aged 70 years and older who were tested in 1990; a subset of the original sample who died between testing occasions; and the sample of 426 who survived with full data sets in 1994 (followed up for a mean 3.5 years). Dispersion, as measured by the within-individual standard deviation of ability scores and by the within-individual deviations from crystallized intelligence for speed, memory and spatial functioning, was significantly correlated with age in all three samples at Wave 1 and at Wave 2 (for the longitudinal sample). The rate at which dispersion increased was not significantly correlated with age. In a more detailed analysis of the 426 survivors, dispersion as a function of age was similar for demented persons within this sample, those without dementia, those with poor and excellent educational levels, and those with a physical disability. Activities of daily living was a predictor of larger-than-average changes in dispersion – but not age, education, or activity. Greater dispersion was associated with faster deterioration in memory and speed performance. Contrary to some recent reports, there was evidence for greater within-individual variability among cognitive domains in older individuals. 相似文献
Many still seem confident that the kind of semantic theory Putnam once proposed for natural kind terms is right. This paper seeks to show that this confidence is misplaced because the general idea underlying the theory is incoherent. Consequently, the theory must be rejected prior to any consideration of its epistemological, ontological or metaphysical acceptability. Part I sets the stage by showing that falsehoods, indeed absurdities, follow from the theory when one deliberately suspends certain devices Putnam built into it , presumably in order to block such entailments. Part II then raises the decisive issue of at what cost these devices do the job they need to do. It argues that - apart from possessing no other motivation than their capacity to block the consequences derived in Part I - they only fulfil this blocking function if they render the theory unable to deal with fiction and related 'make-believe' activities. Part III indicates the affinity Putnam's account has with the classically 'denotative' view of meaning, and thus how its weaknesses may be seen as a variant of the classical weakness of 'denotative' approaches. It concludes that the theory is a conceptual muddle. 相似文献
Current interpretations of Heidegger's notion of das Man are caught in a dilemma: either they cannot accommodate the ontological status Heidegger accords it or they cannot explain his negative evaluation of it, in which it is treated as ontic. This paper uses Simmel's agonistic account of human sociality to integrate the ontological and the ontic, indeed perjorative aspects of Heidegger's account. Section I introduces the general problem, breaks the exclusive link of Heidegger's account to Kierkegaard and delineates the general form of a solution. Section II then sketches Simmel's conception of sociology and sociality. Section III determines what Heidegger is trying to do in Chapter Four of Division I in Being and Time in order to formulate a strictly ontological account of das Man. Section IV uses Simmel's account of sociality to build into this ontological account an inherent tendency to display the negative features Heidegger ascribes to das Man. In conclusion, section V points to how the proposed account of das Man intimates the character of fundamental ontology as nascently a form of critical theory. It also explains the extent to which Heidegger's perjorative characterisations of das Man and the Man-selbst are legitimate. 相似文献
We developed and pilot-tested the first online psycho-educational intervention that specifically targets people with a family history of depression (‘LINKS’). LINKS provides genetic risk information and evidence-rated information on preventive strategies for depression and incorporates a risk assessment tool and several videos using professional actors. LINKS was pilot-tested in the general practitioner (GP) setting. The patient sample included people with a family history of at least one first-degree relative (FDR) with major depressive disorder (MDD) or bipolar disorder (BD). Patients attending participating GP practices were invited to enroll in the study by letter from their GP. Patients who self-identified as having at least one first-degree relative (FDR) with MDD or BD were eligible. Patients completed questionnaires, pre-post viewing LINKS, with measures assessing satisfaction, relevance, emotional impact and perceived improvement of understanding. Six GP practices participated, and 24 patients completed both questionnaires. Of these, all reported that they were satisfied or very satisfied with LINKS, and 74 % reported that LINKS met their expectations, and 21 % that it exceeded their expectations. LINKS was judged highly acceptable by this sample of GP attendees, and results indicate that an assessment of its effectiveness in a larger controlled trial is warranted. 相似文献
Odor identification ability and cognition were measured in a population-based cohort of 1,222 very old twins and singletons, including 91 centenarians. Heritability for identifying odors was low, in contrast to that for cognition. Common genes were found to contribute to both olfaction and cognition. In a multiple regression model, sex, age, cognitive function, and smoking, but not APOEε4 status, were significant predictors of the olfactory test scores (all ps < 0.001). This study, along with data from other studies, suggests that indices of heritability for odor identification decline with age, likely reflecting adverse environmental influences on the smell system. 相似文献
Research suggests opposite epidemiological forces in religion and health: (1). Faith seems to move mountains in the sense that religion is associated with positive health outcomes. (2). Mountains of bad health seem to move faith. We reflected on these forces in a population of 3000 young Danish twins in which all religiosity measures were associated with severe disease. We believe the reason for this novel finding is that the sample presents as a particularly secular population-based study and that the second epidemiological force has gained the upper hand in this sample. We suggest that all cross-sectional research on religion and health should be interpreted in light of such opposite epidemiological forces potentially diluting each other.
The left inferior frontal gyrus (LIFG) is crucially has been found to be involved in syntactic processing of various kinds. This study investigates the cortical effects of two types of syntactic processes: (i) Reconstruction in ellipsis (recovery of left-out material given by context, More people have been to Paris than […] to Oslo), using pseudo-elliptical structures (‘dead ends’) as control (More people have been to Paris than I have). (ii) Reanalysis in the face of structural ambiguity in syntactic ‘garden paths’, where the parser initially assigns an incorrect structure and is forced to reanalyze. Reanalysis and reconstruction require additional syntactic processing and were predicted to increase activation in areas otherwise involved in structural computation: LIFG (BA 44, 45), premotor BA 6, and posterior temporal BA 21, 22. This was borne out. The results showed an interaction effect of the types of construction in all three areas reflecting syntactic processing. 相似文献